Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Veeravan Mahadomrongkul"'
Autor:
Sarah M. Rothman, Keith Q. Tanis, Pallavi Gandhi, Vladislav Malkov, Jacob Marcus, Michelle Pearson, Richard Stevens, Jason Gilliland, Christopher Ware, Veeravan Mahadomrongkul, Elaine O’Loughlin, Gonzalo Zeballos, Roger Smith, Bonnie J. Howell, Joel Klappenbach, Matthew Kennedy, Christian Mirescu
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)
Abstract Background Alzheimer’s disease (AD) is a chronic neurodegenerative disease with pathological hallmarks including the formation of extracellular aggregates of amyloid-beta (Aβ) known as plaques and intracellular tau tangles. Coincident wit
Externí odkaz:
https://doaj.org/article/8e009419f5ab45f69aae66002d9935b3
Autor:
Nicholas B. Hastings, Xiaohai Wang, Lixin Song, Brent D. Butts, Diane Grotz, Richard Hargreaves, J. Fred Hess, Kwok-Lam Karen Hong, Cathy Ruey-Ruey Huang, Lynn Hyde, Maureen Laverty, Julie Lee, Diane Levitan, Sherry X. Lu, Maureen Maguire, Veeravan Mahadomrongkul, Ernest J. McEachern, Xuesong Ouyang, Thomas W. Rosahl, Harold Selnick, Michaela Stanton, Giuseppe Terracina, David J. Vocadlo, Ganfeng Wang, Joseph L. Duffy, Eric M. Parker, Lili Zhang
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-16 (2017)
Abstract Background Hyperphosphorylation of microtubule-associated protein tau is a distinct feature of neurofibrillary tangles (NFTs) that are the hallmark of neurodegenerative tauopathies. O-GlcNAcylation is a lesser known post-translational modifi
Externí odkaz:
https://doaj.org/article/1ce645702743455b9fc3c2ca7c604062
Autor:
Pallavi Gandhi, Elaine O’Loughlin, Jacob Marcus, Veeravan Mahadomrongkul, Richard C. Stevens, Jason Da Gilliland, Christopher Ware, Bonnie J. Howell, Keith Q. Tanis, Gonzalo Zeballos Zeballos, Joel A. Klappenbach, Michelle Pearson, Sarah M. Rothman, Christian Mirescu, Matthew E. Kennedy, Roger Smith, Vladislav A. Malkov
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)
Background Alzheimer’s disease (AD) is a chronic neurodegenerative disease with pathological hallmarks including the formation of extracellular aggregates of amyloid-beta (Aβ) known as plaques and intracellular tau tangles. Coincident with the for
Autor:
Julie Lee, Sherry X. Lu, Maureen Laverty, Brent D. Butts, Diane Grotz, Richard Hargreaves, Michaela C. Stanton, J. Fred Hess, Ernest J. McEachern, Ganfeng Wang, Giuseppe Terracina, Diane Levitan, Xuesong Ouyang, Lynn A. Hyde, Lili Zhang, Joseph L. Duffy, Harold G. Selnick, Thomas W. Rosahl, Kwok-Lam Karen Hong, Nicholas B. Hastings, Cathy Ruey-Ruey Huang, David J. Vocadlo, Xiaohai Wang, Lixin Song, Veeravan Mahadomrongkul, Maureen Maguire, Eric M. Parker
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-16 (2017)
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-16 (2017)
Background Hyperphosphorylation of microtubule-associated protein tau is a distinct feature of neurofibrillary tangles (NFTs) that are the hallmark of neurodegenerative tauopathies. O-GlcNAcylation is a lesser known post-translational modification of
Autor:
Hastings, Nicholas, Xiaohai Wang, Lixin Song, Butts, Brent, Grotz, Diane, Hargreaves, Richard, J. Fred Hess, Kwok-Lam Hong, Huang, Cathy, Hyde, Lynn, Laverty, Maureen, Lee, Julie, Levitan, Diane, Lu, Sherry, Maguire, Maureen, Veeravan Mahadomrongkul, McEachern, Ernest, Xuesong Ouyang, Rosahl, Thomas, Selnick, Harold, Stanton, Michaela, Terracina, Giuseppe, Vocadlo, David, Ganfeng Wang, Duffy, Joseph, Parker, Eric, Zhang, Lili
Detection of O-tau in HEK293 cell lysates and in mouse brain homogenates using antibody 3925. A. Western blot analysis of O-tau in HEK293 cells. HEK293 cells were transiently transfected with pcDNA3.1 vector alone, with pcDNA3.1 vector containing hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33346d22395b4f00afee1ae54c23bdc1
Autor:
Hastings, Nicholas, Xiaohai Wang, Lixin Song, Butts, Brent, Grotz, Diane, Hargreaves, Richard, J. Fred Hess, Kwok-Lam Hong, Huang, Cathy, Hyde, Lynn, Laverty, Maureen, Lee, Julie, Levitan, Diane, Lu, Sherry, Maguire, Maureen, Veeravan Mahadomrongkul, McEachern, Ernest, Xuesong Ouyang, Rosahl, Thomas, Selnick, Harold, Stanton, Michaela, Terracina, Giuseppe, Vocadlo, David, Ganfeng Wang, Duffy, Joseph, Parker, Eric, Zhang, Lili
Generation of OGA iKD mice [36, 37]. (DOCX 117 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4230ed8f3367e7a6da24c12d5f477526
Autor:
Hastings, Nicholas, Xiaohai Wang, Lixin Song, Butts, Brent, Grotz, Diane, Hargreaves, Richard, J. Fred Hess, Kwok-Lam Hong, Huang, Cathy, Hyde, Lynn, Laverty, Maureen, Lee, Julie, Levitan, Diane, Lu, Sherry, Maguire, Maureen, Veeravan Mahadomrongkul, McEachern, Ernest, Xuesong Ouyang, Rosahl, Thomas, Selnick, Harold, Stanton, Michaela, Terracina, Giuseppe, Vocadlo, David, Ganfeng Wang, Duffy, Joseph, Parker, Eric, Zhang, Lili
Analysis of OGA mRNA expression in OGA iKD and littermate WT mice after treatment for 10 days with or without doxycycline. shRNA-mediated knock-down of OGA was achieved by in-diet treatment with doxycycline for 10 days as described in Additional file
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32bbf54359f471ae7fb23692f7336198
Publikováno v:
The Journal of Comparative Neurology. 505:352-362
Mice with knock-in of two mutations that affect beta amyloid processing and levels (2xKI) exhibit impaired spatial memory by 9–12 months of age, together with synaptic plasticity dysfunction in the hippocampus. The goal of this study was to identif
Publikováno v:
Brain Research. 963:139-149
Past in vitro studies have used immunofluorescence to show increased clustering of the NR1 subunits of NMDA receptors (NMDAR) following NMDAR blockade, indicating that NMDARs self-regulate trafficking to and from spines. However, since a substantial
Autor:
Morgen Peck, Nicolas Limthong, Hiroki Taniguchi, Veeravan Mahadomrongkul, Peter Scheiffele, Chiye Aoki, Leora Gollan, Elizabeth Dobler, Francisco G. Scholl
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(11)
The formation of neuronal circuits during development involves a combination of synapse stabilization and elimination events. Synaptic adhesion molecules are thought to play an important role in synaptogenesis, and several trans-synaptic adhesion sys