Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Veera Venkata Naga Phani Babu, Tiruveedhula"'
Autor:
Md Toufiqur Rahman, Veera Venkata Naga Phani Babu Tiruveedhula, Michael Rajesh Stephen, Sundari K. Rallapalli, Kamal P. Pandey, James M. Cook
Publikováno v:
Molecules, Vol 27, Iss 5, p 1738 (2022)
The unification of the general synthetic strategy regarding the important and emerging group of C-19 methyl-substituted sarpagine/macroline alkaloids has culminated in the completion of the total synthesis of several bioactive alkaloids. Key transfor
Externí odkaz:
https://doaj.org/article/9faea352b388405580b76cb1c2e0624e
Autor:
Jovana, Aranđelović, Anja, Santrač, Bojan, Batinić, Lidija, Todorović, Vladimir, Stevanović, Veera Venkata Naga Phani Babu, Tiruveedhula, Dishary, Sharmin, Farjana, Rashid, Boban, Stanojević, James M, Cook, Miroslav M, Savić
Publikováno v:
CNS neurosciencetherapeutics. 28(11)
GABAergic modulation involved in cognitive processing appears to be substantially changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to assess if negative and positive allosteric modulators of α5 GABAAfter 10-day treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a0f5bfeab7c3e2900c1567c9715ff4c
https://pubmed.ncbi.nlm.nih.gov/35822698
https://pubmed.ncbi.nlm.nih.gov/35822698
Autor:
Jovana Aranđelović, Anja Santrač, Bojan Batinić, Lidija Todorović, Vladimir Stevanović, Veera Venkata Naga Phani Babu Tiruveedhula, Dishary Sharmin, Farjana Rashid, Boban Stanojević, James M. Cook, Miroslav M. Savić
Publikováno v:
CNS Neuroscience & Therapeutics
Aims: GABAergic modulation involved in cognitive processing appears to be substan- tially changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to assess if negative and positive allosteric modulators of α5 GABA A recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c943b090e01bac0161b9e7ae8937e9b
http://farfar.pharmacy.bg.ac.rs/bitstream/id/9974/bitstream_9974.pdf
http://farfar.pharmacy.bg.ac.rs/bitstream/id/9974/bitstream_9974.pdf
Autor:
Margot Ernst, Veera Venkata Naga Phani Babu Tiruveedhula, Aleksandar Obradovic, Miroslav M. Savić, Tamara Stankovic, Bojan Marković, Michael Rajesh Stephen, Petra Scholze, James M. Cook, Guanguan Li, Revathi Kodali, Bojan Batinić
Publikováno v:
European Neuropsychopharmacology. 28:903-914
It is unclear whether GABAA receptors (GABAARs) that contain the α3-subunit are substantially involved in the anxiolytic effects of benzodiazepines (BDZs). In the present study, we tested YT-III-31, a newer BDZ ligand with functional preference for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25a23dc547c8818d1b7a1789c19f2c83
https://doi.org/10.1016/j.euroneuro.2018.05.014
https://doi.org/10.1016/j.euroneuro.2018.05.014
Autor:
Jeffrey M. Schkeryantz, Justin N. Siemian, J. S. McDermott, John D. Crawford, Xingjie Ping, D. C. Airey, Veera Venkata Naga Phani Babu Tiruveedhula, Scott D. Gleason, Michael J. Krambis, Rok Cerne, Kashi Reddy Methuku, Timothy M. Jones, J. Hobbs, Michael M. Poe, A. I. Alatorre, Guanguan Li, Jeffrey M. Witkin, Xiaoming Jin, James M. Cook, Jeffrey W. Cramer, Janet L. Fisher, Jodi L. Smith
Publikováno v:
Neuropharmacology. 137:332-343
HZ-166 has previously been characterized as an α2,3-selective GABAA receptor modulator with anticonvulsant, anxiolytic, and anti-nociceptive properties but reduced motor effects. We discovered a series of ester bioisosteres with reduced metabolic li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4f48fd4583fd27544bef626b6da5b08
https://doi.org/10.1016/j.neuropharm.2018.05.006
https://doi.org/10.1016/j.neuropharm.2018.05.006
Autor:
Marjorie C. Gondré-Lewis, Kaitlin T. Warnock, Hong Wang, Harry L. June, Kimberly A. Bell, Holger Rabe, Veera Venkata Naga Phani Babu Tiruveedhula, James Cook, Hartmut Lüddens, Laure Aurelian
Publikováno v:
Stress. 19:235-247
Childhood stress and trauma are associated with substance use disorders in adulthood, but the neurological changes that confer increased vulnerability are largely unknown. In this study, maternal separation (MS) stress, restricted to the pre-weaning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3088d497f3400b83dbd590afd137cf
https://doi.org/10.3109/10253890.2016.1160280
https://doi.org/10.3109/10253890.2016.1160280
Autor:
Guanguan Li, Xia Li, Veera Venkata Naga Phani Babu Tiruveedhula, Lalit K. Golani, Kashi Reddy Methuku, Toufiqur Rahman, Janet L. Fisher, Jeffrey M. Schkeryantz, Scott D. Gleason, Michael M. Poe, Rok Cerne, James M. Cook, Jeffrey M. Witkin
Publikováno v:
Pharmacology, biochemistry, and behavior. 170
Data from transgenic animals and novel pharmacological agents has realigned scientific scrutiny on the therapeutic potential of positive allosteric modulators (PAMs) of α2/3-containing GABAA receptors. Evidence for analgesic, anticonvulsant, and anx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea83eff2899ff3bef947eda7b32cff7
https://pubmed.ncbi.nlm.nih.gov/29715490
https://pubmed.ncbi.nlm.nih.gov/29715490
Autor:
Veera Venkata Naga Phani Babu Tiruveedhula, Rajwana Jahan, Claire Mouser, James M. Cook, Lalit K. Golani, Jodi L. Smith, Guanguan Li, Rok Cerne, J. Hobbs, Xingjie Ping, Farjana Rashid, Xiaoming Jin, Jeffrey M. Witkin
Publikováno v:
Brain Research. 1722:146356
The need for improved antiepileptics is clearly mandated despite the existence of multiple existing medicines from different chemical and mechanistic classes. Standard of care agents do not fully control epilepsies and have a variety of side-effect a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d3152bfcd2f8dd133df5fbb2c476ce
https://doi.org/10.1016/j.brainres.2019.146356
https://doi.org/10.1016/j.brainres.2019.146356
Autor:
Ojas A. Namjoshi, Liana M. Matson, Harry L. June, Meredith Halcomb, Michael L. Van Linn, David Scott O’Tousa, James M. Cook, Kaitlin T. Warnock, Nicholas J. Grahame, Veera Venkata Naga Phani Babu Tiruveedhula
Publikováno v:
Addiction Biology. 20:236-247
Approximately 30% of current drinkers in the United States drink excessively, and are referred to as problem/hazardous drinkers. These individuals, who may not meet criteria for alcohol abuse or dependence, comprise binge, heavy drinkers, or both. Gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac2e7d8371a83615555522cbf6a67e2
https://doi.org/10.1111/adb.12100
https://doi.org/10.1111/adb.12100
Publikováno v:
Molecules, Vol 21, Iss 11, p 1525 (2016)
Bisindole natural products consist of two monomeric indole alkaloid units as their obligate constituents. Bisindoles are more potent with respect to their biological activity than their corresponding monomeric units. In addition, the synthesis of bis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45c3c4b973c711f8c1d8a9c1cc95ee9
http://www.mdpi.com/1420-3049/21/11/1525
http://www.mdpi.com/1420-3049/21/11/1525