Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Veera K. Ojala"'
Autor:
Deepankar Chakroborty, Veera K. Ojala, Anna M. Knittle, Jasmin Drexler, Mahlet Z. Tamirat, Regina Ruzicka, Karin Bosch, Johanna Woertl, Susanne Schmittner, Laura L. Elo, Mark S. Johnson, Kari J. Kurppa, Flavio Solca, Klaus Elenius
Publikováno v:
Cancer Research Communications. 2:10-27
Despite the relatively high frequency of somatic ERBB4 mutations in various cancer types, only a few activating ERBB4 mutations have been characterized, primarily due to lack of mutational hotspots in the ERBB4 gene. Here, we utilized our previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b50f9b74260d251a434e3536636cca24
https://doi.org/10.1158/2767-9764.crc-21-0021
https://doi.org/10.1158/2767-9764.crc-21-0021
Autor:
Johannes A.M. Merilahti, Maarit Kortesoja, Katri Vaparanta, Veera K. Ojala, Klaus Elenius, Jürgen Kast, Kari J. Kurppa, Shujun Lin, Peppi Kirjalainen, Denis Tvorogov, Anna M. Knittle, Arto T. Pulliainen
Publikováno v:
J Biol Chem
ERBB4 is a member of the epidermal growth factor receptor (EGFR)/ERBB subfamily of receptor tyrosine kinases that regulates cellular processes including proliferation, migration, and survival. ERBB4 signaling is involved in embryogenesis and homeosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84234e32f3e4944bdbbeb23e9d10c02e
https://doi.org/10.1074/jbc.ra119.010925
https://doi.org/10.1074/jbc.ra119.010925
Autor:
Antti Kukkula, Veera K. Ojala, Lourdes M. Mendez, Lea Sistonen, Klaus Elenius, Maria Sundvall
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4402, p 4402 (2021)
Cancers, Vol 13, Iss 4402, p 4402 (2021)
Simple Summary The small ubiquitin-like modifier (SUMO) pathway regulates the hallmark properties of cancer cells. Moreover, alterations in activity and in levels of SUMO machinery components have been observed in human cancer. Due to the reversible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ff64bfefe9180b52cac0c215a3572a7b
http://europepmc.org/articles/PMC8431684
http://europepmc.org/articles/PMC8431684
Autor:
Marika Koivu, Ilkka Paatero, Mahlet Z. Tamirat, Veera K. Ojala, Jussi Koivunen, Mark S. Johnson, Klaus Elenius, Laura L. Elo, Kari J. Kurppa, Deepankar Chakroborty, Pasi A. Jänne
Publikováno v:
Journal of Biological Chemistry. 294:9377-9389
Cancer tissues harbor thousands of mutations, and a given oncogene may be mutated at hundreds of sites, yet only a few of these mutations have been functionally tested. Here, we describe an unbiased platform for the functional characterization of tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1322ebbdd911f468bfe58924eacb15d
https://doi.org/10.1074/jbc.ra118.006336
https://doi.org/10.1074/jbc.ra118.006336
Publikováno v:
Cancer Research. 82:153-153
Introduction: Cancer tissues harbor thousands of mutations, and a given oncogene may be mutated at hundreds of sites across different samples. The discovery of most of the currently known driver mutations has been facilitated by their accumulation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c0b7465d42d75dbe563e945f6d21bd6
https://doi.org/10.1158/1538-7445.am2022-153
https://doi.org/10.1158/1538-7445.am2022-153
Publikováno v:
Molecular Biology of the Cell
Receptor tyrosine kinases (RTKs) can signal via regulated intramembrane proteolysis, leading to release of an intracellular receptor fragment with functional activity. A system-wide screen covering 45 of the 55 human RTKs identified 12 novel gamma-se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc50c6025efff52f904bca0e3fb38fe
https://doi.org/10.1091/mbc.e17-04-0261
https://doi.org/10.1091/mbc.e17-04-0261