Use of diffusion tensor imaging to assess the impact of normobaric hyperoxia within at-risk pericontusional tissue after traumatic brain injury

Autor: Veenith, TV, Carter, EL, Grossac, J, Newcombe, VF, Outtrim, JG, Nallapareddy, S, Lupson, V, Correia, MM, Mada, MM, Williams, GB, Menon, DK, Coles, JP

Ischemia and metabolic dysfunction remain important causes of neuronal loss after head injury, and we have shown that normobaric hyperoxia may rescue such metabolic compromise. This study examines the impact of hyperoxia within injured brain using di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1708bc71c805bf12369e1c81643922d5

Development of a high-sensitivity ELISA detecting IgG, IgA and IgM antibodies to the SARS-CoV-2 spike glycoprotein in serum and saliva.

Autor: Faustini SE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Jossi SE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Perez-Toledo M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Shields AM; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Allen JD; School of Biological Sciences, University of Southampton, Southampton, UK., Watanabe Y; School of Biological Sciences, University of Southampton, Southampton, UK.; Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, Oxford, UK., Newby ML; School of Biological Sciences, University of Southampton, Southampton, UK., Cook A; Binding Site Group Ltd, Birmingham, UK., Willcox CR; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Salim M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Goodall M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Heaney JL; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Marcial-Juarez E; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Morley GL; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Torlinska B; Institute of Applied Health Research, University of Birmingham, Birmingham, UK., Wraith DC; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Veenith TV; Department of Critical Care Medicine, University Hospitals Birmingham NHS Trust, Birmingham, UK., Harding S; Binding Site Group Ltd, Birmingham, UK., Jolles S; Immunodeficiency Centre for Wales, Cardiff, UK., Ponsford MJ; Immunodeficiency Centre for Wales, Cardiff, UK., Plant T; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Huissoon A; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Department of Immunology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., O'Shea MK; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Willcox BE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Drayson MT; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Crispin M; School of Biological Sciences, University of Southampton, Southampton, UK., Cunningham AF; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Richter AG; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.

Publikováno v: Immunology [Immunology] 2021 Sep; Vol. 164 (1), pp. 135-147. Date of Electronic Publication: 2021 May 24.

Detection of antibodies to the SARS-CoV-2 spike glycoprotein in both serum and saliva enhances detection of infection.

Autor: Faustini SE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Jossi SE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Perez-Toledo M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Shields AM; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Allen JD; School of Biological Sciences, University of Southampton, Southampton SO17 1BJ, U.K., Watanabe Y; School of Biological Sciences, University of Southampton, Southampton SO17 1BJ, U.K.; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, U.K., Newby ML; School of Biological Sciences, University of Southampton, Southampton SO17 1BJ, U.K., Cook A; Binding Site Group Ltd, Birmingham, U.K., Willcox CR; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Salim M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Goodall M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Heaney JL; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Marcial-Juarez E; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Morley GL; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, U.K., Torlinska B; Institute of Applied Health Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, U.K., Wraith DC; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Veenith TV; Department of Critical Care Medicine, University Hospitals Birmingham NHS Trust, Birmingham, B15 2TH, U.K., Harding S; Binding Site Group Ltd, Birmingham, U.K., Jolles S; Immunodeficiency Centre for Wales, Cardiff, U.K., Ponsford MJ; Immunodeficiency Centre for Wales, Cardiff, U.K., Plant T; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Huissoon A; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K.; Department of Immunology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, U.K., O'Shea MK; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Willcox BE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Drayson MT; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Crispin M; School of Biological Sciences, University of Southampton, Southampton SO17 1BJ, U.K., Cunningham AF; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K., Richter AG; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, U.K.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2020 Jun 18. Date of Electronic Publication: 2020 Jun 18.

Spatial and Temporal Pattern of Ischemia and Abnormal Vascular Function Following Traumatic Brain Injury.

Autor: Launey Y; Division of Anaesthesia, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.; Department of Anaesthesia and Critical Care Medicine, Centre Hospitalier Universitaire de Rennes, Rennes, France., Fryer TD; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Hong YT; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Steiner LA; Division of Anaesthesia, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.; Department of Anaesthesiology, University Hospital Basel, Basel, Switzerland.; Department of Clinical Research, University of Basel, Basel, Switzerland., Nortje J; Division of Anaesthesia, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.; Department of Anaesthesia, Norfolk and Norwich University Hospitals National Health Service Foundation Trust, Norwich, United Kingdom., Veenith TV; Division of Anaesthesia, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.; Birmingham Acute Care Research Group, Department of Critical Care Medicine, Queen Elizabeth Hospital, University of Birmingham, Birmingham, United Kingdom., Hutchinson PJ; Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Ercole A; Division of Anaesthesia, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Gupta AK; Division of Anaesthesia, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Aigbirhio FI; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Pickard JD; Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Coles JP; Division of Anaesthesia, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Menon DK; Division of Anaesthesia, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.

Publikováno v: JAMA neurology [JAMA Neurol] 2020 Mar 01; Vol. 77 (3), pp. 339-349.

Pathophysiologic Mechanisms of Cerebral Ischemia and Diffusion Hypoxia in Traumatic Brain Injury.

Autor: Veenith TV; Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England2Department of Critical Care Medicine, University Hospital of Birmingham National Health Service Trust, Queen Elizabeth Medical Centre, Birmingham, England., Carter EL; Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Geeraerts T; Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England3Department of Anesthesiology and Critical Care, University Hospital of Toulouse, Toulouse, France., Grossac J; Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England3Department of Anesthesiology and Critical Care, University Hospital of Toulouse, Toulouse, France., Newcombe VF; Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Outtrim J; Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Gee GS; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Lupson V; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Smith R; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Aigbirhio FI; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Fryer TD; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Hong YT; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Menon DK; Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Coles JP; Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England.

Publikováno v: JAMA neurology [JAMA Neurol] 2016 May 01; Vol. 73 (5), pp. 542-50.