Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Vedrana S. Susulic"'
Autor:
Philip E Silkoff, Dave Singh, J Mark FitzGerald, Andreas Eich, Andrea Ludwig-Sengpiel, Geoffrey C Chupp, Vibeke Backer, Celeste Porsbjerg, Pierre-Olivier Girodet, Mark T Dransfield, Frederic Baribaud, Vedrana S Susulic, Matthew J Loza
Publikováno v:
Biomarker Insights, Vol 12 (2017)
Rationale: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease, and development of novel therapeutics requires an understanding of pathophysiologic phenotypes. Objectives: The purpose of the Airways Disease Endotyping for Personal
Externí odkaz:
https://doaj.org/article/9367da2f9e8f433c9c01d12e25f3f173
Autor:
J. Mark FitzGerald, Richard Leigh, Joel N. Kline, Stephen Lam, Matthew J. Loza, Andreas Eich, Frédéric Baribaud, Patrick Berger, P. Chanez, Philip E. Silkoff, Dave Singh, Vedrana S. Susulic, Steven G. Kelsen, Elliot S. Barnathan, Michel Laviolette, Azra Hussaini, Irina Strambu, William J. Calhoun, Andrea Ludwig-Sengpiel, Geoffrey Chupp, Mark T. Dransfield, Vibeke Backer, Pierre Olivier Girodet, Celeste Porsbjerg
Publikováno v:
Journal of Allergy and Clinical Immunology. 140:710-719
Background The Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study profiled patients with mild, moderate, and severe asthma and nonatopic healthy control subjects. Objective We explored this data set to define type 2 inflammation b
Autor:
Frédéric Baribaud, Mark T. Dransfield, Celeste Porsbjerg, Andreas Eich, Geoffrey C. Chupp, Pierre Olivier Girodet, Dave Singh, Vedrana S. Susulic, Matthew J. Loza, Andrea Ludwig-Sengpiel, J. Mark FitzGerald, Vibeke Backer, Philip E. Silkoff
Publikováno v:
Silkoff, P E, Singh, D, FitzGerald, J M, Eich, A, Ludwig-Sengpiel, A, Chupp, G C, Backer, V, Porsbjerg, C, Girodet, P-O, Dransfield, M T, Baribaud, F, Susulic, V S & Loza, M J 2017, ' Inhaled Steroids and Active Smoking Drive Chronic Obstructive Pulmonary Disease Symptoms and Biomarkers to a Greater Degree Than Airflow Limitation ', Biomarker Insights, vol. 12, pp. 1-12 . https://doi.org/10.1177/1177271917730306
Biomarker Insights, Vol 12 (2017)
Silkoff, P E, Singh, D, FitzGerald, J M, Eich, A, Ludwig-Sengpiel, A, Chupp, G C, Backer, V, Porsbjerg, C, Girodet, P O, Dransfield, M T, Baribaud, F, Susulic, V S & Loza, M J 2017, ' Inhaled Steroids and Active Smoking Drive Chronic Obstructive Pulmonary Disease Symptoms and Biomarkers to a Greater Degree Than Airflow Limitation ', Biomarker Insights, vol. 12 . https://doi.org/10.1177/1177271917730306
Biomarker Insights
Biomarker Insights, Vol 12 (2017)
Silkoff, P E, Singh, D, FitzGerald, J M, Eich, A, Ludwig-Sengpiel, A, Chupp, G C, Backer, V, Porsbjerg, C, Girodet, P O, Dransfield, M T, Baribaud, F, Susulic, V S & Loza, M J 2017, ' Inhaled Steroids and Active Smoking Drive Chronic Obstructive Pulmonary Disease Symptoms and Biomarkers to a Greater Degree Than Airflow Limitation ', Biomarker Insights, vol. 12 . https://doi.org/10.1177/1177271917730306
Biomarker Insights
Rationale: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease, and development of novel therapeutics requires an understanding of pathophysiologic phenotypes. Objectives: The purpose of the Airways Disease Endotyping for Personal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911a4502c421436fd8c56fa2ef2480f6
https://curis.ku.dk/portal/da/publications/inhaled-steroids-and-active-smoking-drive-chronic-obstructive-pulmonary-disease-symptoms-and-biomarkers-to-a-greater-degree-than-airflow-limitation(837b2bb8-09e9-41f4-b51a-3d248aee18de).html
https://curis.ku.dk/portal/da/publications/inhaled-steroids-and-active-smoking-drive-chronic-obstructive-pulmonary-disease-symptoms-and-biomarkers-to-a-greater-degree-than-airflow-limitation(837b2bb8-09e9-41f4-b51a-3d248aee18de).html
Autor:
M. Laviolette, Pascal Chanez, Pierre-Olivier Girodet, Steven G. Kelsen, Sumita Khatri, JM FitzGerald, Elliot S. Barnathan, Celeste Porsbjerg, Joel N. Kline, Vedrana S. Susulic, Philip E. Silkoff, Vibeke Backer, Dave Singh, Matthew J. Loza, Patrick Berger, F. Baribaud
Publikováno v:
Silkoff, P E, Laviolette, M, Singh, D, FitzGerald, J M, Kelsen, S, Backer, V, Porsbjerg, C, Girodet, P O, Berger, P, Kline, J N, Khatri, S, Chanez, P, Susulic, V S, Barnathan, E S, Baribaud, F, Loza, M J & ADEPT Investigators 2016, ' Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study ', Respiratory research, vol. 17, pp. 43 . https://doi.org/10.1186/s12931-016-0360-5
Respiratory Research
Respiratory Research
BACKGROUND: Asthma is a biologically heterogeneous disease and development of novel therapeutics requires understanding of pathophysiologic phenotypes. There is uncertainty regarding the stability of clinical characteristics and biomarkers in asthma
Autor:
Carrie Brodmerkel, Anuk Das, Joel N. Kline, Frédéric Baribaud, Vibeke Backer, Patrick Berger, Steven Steven Kelsen, William J. Calhoun, Sumita Khatri, Celeste Porsbjerg, Philip E. Silkoff, David Singh, Richard Leigh, Michel Laviolette, Stephen Lam, Geoffrey L. Chupp, Elliot S. Barnathan, Azra Hussaini, Andreas Eich, Mark Curran, Matthew J. Loza, Vedrana S. Susulic, J. Mark FitzGerald, Pierre-Olivier Girodet, Mark T. Dransfield, Irina Strambu, Andrea Ludwig-Sengpiel, Pascal Chanez, Kevin J. Petty
Publikováno v:
5.1 Airway Pharmacology and Treatment.
Rationale: The ADEPT study aimed to correlate clinical features and accessible biomarkers with molecular characteristics by profiling asthmatics across severities and healthy nonatopic volunteers (HVs). This report focuses on the identification of mu
Autor:
Sona Kang, Wendy S. Wright, Ormond A. MacDougald, Vedrana S. Susulic, Tyler C. Prestwich, Vernon W. Dolinsky, Kenneth A. Longo, Shian Huey Chiang, Christina N. Bennett, Isabelle Gerin, Charles F. Burant, Catherine Gress
Publikováno v:
Diabetes. 56:295-303
The Wnt family of secreted signaling molecules has profound effects on diverse developmental processes, including the fate of mesenchymal progenitors. While activation of Wnt signaling blocks adipogenesis, inhibition of endogenous Wnt/beta-catenin si
Autor:
U-Biopred Investigators, Matthew J. Loza, Frederik Baribaud, Philip E. Silkoff, Elliot S. Barnathan, Vedrana S. Susulic, Ratko Djukanovic, Peter J. Sterk, Ian M. Adcock, K.F. Chung, Charles Auffray
Publikováno v:
S103
S102
S102
ADEPT (Airways Disease Endotyping for Personalized Therapeutics) and U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) are independent asthma biomarker studies that aim to enable personalization of therapies
Autor:
Barbara E. Corkey, Barbara A. Cunningham, Jean Himms-Hagen, Danica Grujic, Bradford B. Lowell, Mary-Ellen Harper, Vedrana S. Susulic
Publikováno v:
Journal of Biological Chemistry. 272:17686-17693
β3-Adrenergic receptors (β3-ARs) are expressed predominantly on white and brown adipocytes, and acute treatment of mice with CL 316,243, a potent and highly selective β3-AR agonist, produces a 2-fold increase in energy expenditure, a 50–100-fold
Autor:
Vedrana S. Susulic, Bradford B. Lowell
Publikováno v:
Current Opinion in Endocrinology and Diabetes. 3:44-50
Autor:
Sotirios K. Karathanasis, David Shuey, Kurt E. Steiner, Lucille LaVallette, Vedrana S. Susulic, Emir Duzic, Liang Chen
Publikováno v:
Endocrinology. 142(5)
Mechanisms of transcriptional regulation of the human beta(3)-adrenergic receptor were studied using SK-N-MC cells, a human neuroblastoma cell line that expresses beta(3)- and beta(1)-adrenergic receptors endogenously. Deletions spanning different po