Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Vedrana S. Susulic"'
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Akademický článek
Inhaled Steroids and Active Smoking Drive Chronic Obstructive Pulmonary Disease Symptoms and Biomarkers to a Greater Degree Than Airflow Limitation
Autor: Philip E Silkoff, Dave Singh, J Mark FitzGerald, Andreas Eich, Andrea Ludwig-Sengpiel, Geoffrey C Chupp, Vibeke Backer, Celeste Porsbjerg, Pierre-Olivier Girodet, Mark T Dransfield, Frederic Baribaud, Vedrana S Susulic, Matthew J Loza
Publikováno v: Biomarker Insights, Vol 12 (2017)
Rationale: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease, and development of novel therapeutics requires an understanding of pathophysiologic phenotypes. Objectives: The purpose of the Airways Disease Endotyping for Personal
Externí odkaz: https://doaj.org/article/9367da2f9e8f433c9c01d12e25f3f173
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3
Inhaled Steroids and Active Smoking Drive Chronic Obstructive Pulmonary Disease Symptoms and Biomarkers to a Greater Degree Than Airflow Limitation
Autor: Frédéric Baribaud, Mark T. Dransfield, Celeste Porsbjerg, Andreas Eich, Geoffrey C. Chupp, Pierre Olivier Girodet, Dave Singh, Vedrana S. Susulic, Matthew J. Loza, Andrea Ludwig-Sengpiel, J. Mark FitzGerald, Vibeke Backer, Philip E. Silkoff
Publikováno v: Silkoff, P E, Singh, D, FitzGerald, J M, Eich, A, Ludwig-Sengpiel, A, Chupp, G C, Backer, V, Porsbjerg, C, Girodet, P-O, Dransfield, M T, Baribaud, F, Susulic, V S & Loza, M J 2017, ' Inhaled Steroids and Active Smoking Drive Chronic Obstructive Pulmonary Disease Symptoms and Biomarkers to a Greater Degree Than Airflow Limitation ', Biomarker Insights, vol. 12, pp. 1-12 . https://doi.org/10.1177/1177271917730306
Biomarker Insights, Vol 12 (2017)
Silkoff, P E, Singh, D, FitzGerald, J M, Eich, A, Ludwig-Sengpiel, A, Chupp, G C, Backer, V, Porsbjerg, C, Girodet, P O, Dransfield, M T, Baribaud, F, Susulic, V S & Loza, M J 2017, ' Inhaled Steroids and Active Smoking Drive Chronic Obstructive Pulmonary Disease Symptoms and Biomarkers to a Greater Degree Than Airflow Limitation ', Biomarker Insights, vol. 12 . https://doi.org/10.1177/1177271917730306
Biomarker Insights
Rationale: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease, and development of novel therapeutics requires an understanding of pathophysiologic phenotypes. Objectives: The purpose of the Airways Disease Endotyping for Personal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911a4502c421436fd8c56fa2ef2480f6
https://curis.ku.dk/portal/da/publications/inhaled-steroids-and-active-smoking-drive-chronic-obstructive-pulmonary-disease-symptoms-and-biomarkers-to-a-greater-degree-than-airflow-limitation(837b2bb8-09e9-41f4-b51a-3d248aee18de).html
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Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study
Autor: M. Laviolette, Pascal Chanez, Pierre-Olivier Girodet, Steven G. Kelsen, Sumita Khatri, JM FitzGerald, Elliot S. Barnathan, Celeste Porsbjerg, Joel N. Kline, Vedrana S. Susulic, Philip E. Silkoff, Vibeke Backer, Dave Singh, Matthew J. Loza, Patrick Berger, F. Baribaud
Publikováno v: Silkoff, P E, Laviolette, M, Singh, D, FitzGerald, J M, Kelsen, S, Backer, V, Porsbjerg, C, Girodet, P O, Berger, P, Kline, J N, Khatri, S, Chanez, P, Susulic, V S, Barnathan, E S, Baribaud, F, Loza, M J & ADEPT Investigators 2016, ' Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study ', Respiratory research, vol. 17, pp. 43 . https://doi.org/10.1186/s12931-016-0360-5
Respiratory Research
BACKGROUND: Asthma is a biologically heterogeneous disease and development of novel therapeutics requires understanding of pathophysiologic phenotypes. There is uncertainty regarding the stability of clinical characteristics and biomarkers in asthma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119866d7335e5ff81668cba89a15456f
https://doi.org/10.1186/s12931-016-0360-5
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Wnt10b Inhibits Obesity in ob/ob and Agouti Mice
Autor: Sona Kang, Wendy S. Wright, Ormond A. MacDougald, Vedrana S. Susulic, Tyler C. Prestwich, Vernon W. Dolinsky, Kenneth A. Longo, Shian Huey Chiang, Christina N. Bennett, Isabelle Gerin, Charles F. Burant, Catherine Gress
Publikováno v: Diabetes. 56:295-303
The Wnt family of secreted signaling molecules has profound effects on diverse developmental processes, including the fate of mesenchymal progenitors. While activation of Wnt signaling blocks adipogenesis, inhibition of endogenous Wnt/beta-catenin si
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79b4e914c0b9e82ff785510137d9653
https://doi.org/10.2337/db06-1339
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Longitudinally Stable, Clinically Defined Clusters of Patients with Asthma Independently Identified in the ADEPT and U-BIOPRED Asthma Studies
Autor: U-Biopred Investigators, Matthew J. Loza, Frederik Baribaud, Philip E. Silkoff, Elliot S. Barnathan, Vedrana S. Susulic, Ratko Djukanovic, Peter J. Sterk, Ian M. Adcock, K.F. Chung, Charles Auffray
Publikováno v: S103
S102
ADEPT (Airways Disease Endotyping for Personalized Therapeutics) and U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) are independent asthma biomarker studies that aim to enable personalization of therapies
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075ca7d9e876a93aac53489043f32472
https://doi.org/10.1513/annalsats.201508-519mg
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β3-Adrenergic Receptors on White and Brown Adipocytes Mediate β3-Selective Agonist-induced Effects on Energy Expenditure, Insulin Secretion, and Food Intake
Autor: Barbara E. Corkey, Barbara A. Cunningham, Jean Himms-Hagen, Danica Grujic, Bradford B. Lowell, Mary-Ellen Harper, Vedrana S. Susulic
Publikováno v: Journal of Biological Chemistry. 272:17686-17693
β3-Adrenergic receptors (β3-ARs) are expressed predominantly on white and brown adipocytes, and acute treatment of mice with CL 316,243, a potent and highly selective β3-AR agonist, produces a 2-fold increase in energy expenditure, a 50–100-fold
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7ac1c1b302267938a969b0c25b6a0db
https://doi.org/10.1074/jbc.272.28.17686
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Expression of the human beta(3)-adrenergic receptor gene in SK-N-MC cells is under the control of a distal enhancer
Autor: Sotirios K. Karathanasis, David Shuey, Kurt E. Steiner, Lucille LaVallette, Vedrana S. Susulic, Emir Duzic, Liang Chen
Publikováno v: Endocrinology. 142(5)
Mechanisms of transcriptional regulation of the human beta(3)-adrenergic receptor were studied using SK-N-MC cells, a human neuroblastoma cell line that expresses beta(3)- and beta(1)-adrenergic receptors endogenously. Deletions spanning different po
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76888a4b96b611b01ffa58eb1ca3d29e
https://pubmed.ncbi.nlm.nih.gov/11316759
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