Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Vedbar S. Khadka"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 9215-9233 (2024)
The thymus, a central lymphoid organ in animals, serves as the site for T cell development, differentiation and maturation, vital to adaptive immunity. The thymus is critical for maintaining tissue homeostasis to protect against tumors and tissue dam
Externí odkaz:
https://doaj.org/article/0050ab48368b47eb8fff14ce6dfc3439
Publikováno v:
Animals, Vol 14, Iss 13, p 1932 (2024)
The gastrointestinal tract has a pivotal role in nutrient absorption, immune function, and overall homeostasis. The ileum segment of the small intestine plays respective roles in nutrient breakdown and absorption. The purpose of this study was to inv
Externí odkaz:
https://doaj.org/article/ecebc1dc02f045fda288feb95cb28e40
Autor:
Hyundong Yoon, Logan S. Dean, Boonyanudh Jiyarom, Vedbar S. Khadka, Youping Deng, Vivek R. Nerurkar, Dominic C. Chow, Cecilia M. Shikuma, Gehan Devendra, Youngil Koh, Juwon Park
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundAlthough our understanding of the immunopathology and subsequent risk and severity of COVID-19 disease is evolving, a detailed account of immune responses that contribute to the long-term consequences of pulmonary complications in COVID-19
Externí odkaz:
https://doaj.org/article/79a2d835cb1b4be18d0846db41694421
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 371 (2023)
The study of liquid biopsy with plasma samples is being conducted to identify biomarkers for clinical use. Exosomes, containing nucleic acids and metabolites, have emerged as possible sources for biomarkers. To evaluate the effectiveness of exosomes
Externí odkaz:
https://doaj.org/article/251f324f8b7e4397a22931518af29b72
Autor:
Bindu Adhikari, Chin N. Lee, Vedbar S. Khadka, Youping Deng, Glen Fukumoto, Mark Thorne, Kyle Caires, Jenee Odani, Birendra Mishra
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Maternal recognition is the crucial step for establishing pregnancy in cattle. This study aims to identify endometrial genes and biological pathways involved in the maternal recognition of pregnancy. Caruncular endometrial tissues
Externí odkaz:
https://doaj.org/article/f3cee4f94ca64ed2a75aee6bbc863431
Autor:
Won Seok Yang, Maisel J. Caliva, Vedbar S. Khadka, Maarit Tiirikainen, Michelle L. Matter, Youping Deng, Joe W. Ramos
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
The 90 kDa ribosomal S6 kinases (RSKs) are serine threonine kinases comprising four isoforms. The isoforms can have overlapping functions in regulation of migration, invasion, proliferation, survival, and transcription in various cancer types. Howeve
Externí odkaz:
https://doaj.org/article/38d53d98a4494cc4bd72ce5ba6de5279
Autor:
Allison Lesher Williams, Chad B. Walton, Blake Pinell, Vedbar S. Khadka, Brandyn Dunn, Katie Lee, M. C. Therese Anagaran, Abigail Avelar, Ralph V. Shohet
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Ischemic heart disease is a leading cause of heart failure and hypoxia inducible factor 1 (HIF1) is a key transcription factor in the response to hypoxic injury. Our lab has developed a mouse model in which a mutated, oxygen-stable form of H
Externí odkaz:
https://doaj.org/article/3358c57a1c804a2fa84edf3e2217d1eb
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7553 (2023)
High-risk benign breast tumors are known to develop breast cancer at high rates. However, it is still controversial whether they should be removed during diagnosis or followed up until cancer development becomes evident. Therefore, this study sought
Externí odkaz:
https://doaj.org/article/d517e613d8824928a55a2c03d1e0d193
Publikováno v:
BMC Bioinformatics, Vol 21, Iss S9, Pp 1-15 (2020)
Abstract Cancer is one of the leading causes of morbidity and mortality in the globe. Microbiological infections account for up to 20% of the total global cancer burden. The human microbiota within each organ system is distinct, and their composition
Externí odkaz:
https://doaj.org/article/2ca4ba51f7c743c882964a409a15b815
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 631-641 (2020)
Identification of microbial composition directly from tumor tissue permits studying the relationship between microbial changes and cancer pathogenesis. We interrogated bacterial presence in tumor and adjacent normal tissue strictly in pairs utilizing
Externí odkaz:
https://doaj.org/article/6475d03f6b7b4908979a6f8464aebce9