Zobrazeno 1 - 10 of 89 pro vyhledávání: '"Ved Prakash, Verma"'
1
Akademický článek
Optimized spirooxindole-pyrazole hybrids targeting the p53-MDM2 interplay induce apoptosis and synergize with doxorubicin in A549 cells
Autor: Mohammad Shahidul Islam, Abdullah Mohammed Al-Majid, Essam Nageh Sholkamy, Assem Barakat, Maurizio Viale, Paola Menichini, Andrea Speciale, Fabrizio Loiacono, Mohammad Azam, Ved Prakash Verma, Sammer Yousuf, Mohamed Teleb
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-23 (2023)
Abstract Recently, cancer research protocols have introduced clinical-stage spirooxindole-based MDM2 inhibitors. However, several studies reported tumor resistance to the treatment. This directed efforts to invest in designing various combinatorial l
Externí odkaz: https://doaj.org/article/3163e75f3ed94e9b89596f628803db7b
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5
Akademický článek
Synthesis, biological evaluation and molecular docking of pyrimidine and quinazoline derivatives of 1,5-benzodiazepine as potential anticancer agents
Autor: Apoorva Misra, Dharma Kishore, Ved Prakash Verma, Sunil Dubey, Subhash Chander, Neha Gupta, Sameer Bhagyawant, Jaya Dwivedi, Zeid A. Alothman, Saikh Mohammad Wabaidur, Swapnil Sharma
Publikováno v: Journal of King Saud University: Science, Vol 32, Iss 2, Pp 1486-1495 (2020)
A new series of Pyrimidine (A, D and F) and quinazoline (B, C and E) analogues of 1,5-benzodiazepines were prepared via its nitrile-derived amidoximes in and nitrilium ions, respectively using one pot Domino reaction with DMAD in presence of DABCO ca
Externí odkaz: https://doaj.org/article/efa9d90479b646f7b7664dbe43b744bf
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8
Fe3O4‐supported sulfonated graphene oxide as a green and magnetically separable nanocatalyst for synthesis of 2-amino-3-cyano-4H-chromene derivatives and their in-silico studies
Autor: Shaily Sharma, Mahesh Meena, Himanshu Sharma, Dinesh Kumar Yadav, Atul Tiwari, Ved Prakash Verma
Publikováno v: Synthetic Communications. 52:1926-1955
Under ultrasound irradiation, 17 examples of 2-Amino-3-cyano-4H-chromene derivatives were prepared via one-pot three components domino Knoevenagel–Michael condensation reaction of aliphatic/aromatic/heterocyclic aldehydes, malononitrile, and α-nap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e6c1c128ae6bbfdb796c7177d5cb24
https://doi.org/10.1080/00397911.2022.2120404
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9
An Ultrasound-Assisted Solvent and Catalyst-Free Synthesis of Structurally Diverse Pyrazole Centered 1,5-disubstituted Tetrazoles via One-Pot Four-Component Reaction
Autor: Rahul Shrivastava, Suman Swami, Neelam Sharma, Arunava Agarwala, Ved Prakash Verma, Atul Pratap Singh
Publikováno v: Letters in Organic Chemistry. 19:795-802
Abstract: 1,5-Disubstituted tetrazoles are vital drug-like scaffolds usually encountered as valuable bioisosteres of the cis-amide bond. In this article, we reported the synthesis of some novel medicinally relevant pyrazole centered 1,5-disubstituted
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6daec485bf271b195762e37d11d41a0
https://doi.org/10.2174/1570178619666211220094516
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