Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ved P. Dwivedi"'
Autor:
Debprasad Chattopadhyay, Gobardhan Das, Ved P. Dwivedi, Debapriya Bhattacharya, Vinod Yadav, Dhiraj K. Singh, Santosh Kumar, Mona Singh, Durbadal Ojha, Anand Ranganathan, Luc Van Kaer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Tuberculosis (TB) remains one of the greatest health concerns worldwide, which has hindered socioeconomic development in certain parts of the world for many centuries. Although current TB therapy, “Directly Observed Treatment Short-course,” is ef
Externí odkaz:
https://doaj.org/article/ef024d6eacc242af9fe22c03f723cdb3
Autor:
Meetu Agarwal, Ashima Bhaskar, Biplab Singha, Suparba Mukhopadhyay, Isha Pahuja, Archna Singh, Shivam Chaturvedi, Nisheeth Agarwal, Ved Prakash Dwivedi, Vinay Kumar Nandicoori
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract The limitations of TB treatment are the long duration and immune-dampening effects of anti-tuberculosis therapy. The Cell wall plays a crucial role in survival and virulence; hence, enzymes involved in its biosynthesis are good therapeutic t
Externí odkaz:
https://doaj.org/article/578dbbd1d59c4fc6ba88486f2c23318f
Autor:
Debasis Sahu, Charu Gupta, Ragothaman M. Yennamalli, Shikha Sharma, Saugata Roy, Sadaf Hasan, Pawan Gupta, Vishnu Kumar Sharma, Sujit Kashyap, Santosh Kumar, Ved Prakash Dwivedi, Xiangli Zhao, Amulya Kumar Panda, Hasi Rani Das, Chuan-Ju Liu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The inhibition of tumor necrosis factor (TNF)-α trimer formation renders it inactive for binding to its receptors, thus mitigating the vicious cycle of inflammation. We designed a peptide (PIYLGGVFQ) that simulates a sequence strand of huma
Externí odkaz:
https://doaj.org/article/88fef488d8d84539acb8cb2babc6bd12
Autor:
Isha Pahuja, Antara Ghoshal, Ahmed Abdallah Okieh, Akanksha Verma, Kriti Negi, Meetu Agarwal, Nidhi Subhash Chandra, Saurabh Kumar Sharma, Ashima Bhaskar, Ved Prakash Dwivedi
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT The host immune responses play a pivotal role in the establishment of long-term memory responses, which effectively aids in infection clearance. However, the prevailing anti-tuberculosis therapy, while aiming to combat tuberculosis (TB), als
Externí odkaz:
https://doaj.org/article/6099b1271ad74eb9bfa8b12dd780f110
Autor:
Debasis Sahu, Charu Gupta, Ragothaman M. Yennamalli, Shikha Sharma, Saugata Roy, Sadaf Hasan, Pawan Gupta, Vishnu Kumar Sharma, Sujit Kashyap, Santosh Kumar, Ved Prakash Dwivedi, Xiangli Zhao, Amulya Kumar Panda, Hasi Rani Das, Chuan-Ju Liu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/d4c50d188bbc4d2dab07f90760871bcf
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mycobacterium tuberculosis (M.tb) effectively manipulates the host processes to establish the deadly respiratory disease, Tuberculosis (TB). M.tb has developed key mechanisms to disrupt the host cell health to combat immune responses and replicate ef
Externí odkaz:
https://doaj.org/article/30c3c1a13d9147c8ae0f4866abdecfff
Autor:
Isha Pahuja, Akanksha Verma, Antara Ghoshal, Suparba Mukhopadhyay, Anjna Kumari, Aishwarya Shaji, Shivam Chaturvedi, Ved Prakash Dwivedi, Ashima Bhaskar
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Tuberculosis (TB) still tops the list of global health burdens even after COVID-19. However, it will sooner transcend the current pandemic due to the prevailing risk of reactivation of latent TB in immunocompromised individuals. The indiscri
Externí odkaz:
https://doaj.org/article/675b2b421b604bc2a35f8590c8d66e10
Autor:
Ashima Bhaskar, Isha Pahuja, Kriti Negi, Akanksha Verma, Antara Ghoshal, Babu Mathew, Gaurav Tripathi, Jaswinder Singh Maras, Shivam Chaturvedi, Ved Prakash Dwivedi
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106644- (2023)
Summary: Bacille Calmette-Guerin (BCG) generates limited long-lasting adaptive memory responses leading to short-lived protection against adult pulmonary tuberculosis (TB). Here, we show that host sirtuin 2 (SIRT2) inhibition by AGK2 significantly en
Externí odkaz:
https://doaj.org/article/b1a568ab7b094d5db897ff8de9f22986
Autor:
Mona Singh, Santosh Kumar, Baldeep Singh, Preeti Jain, Anjna Kumari, Isha Pahuja, Shivam Chaturvedi, Durbaka Vijay Raghava Prasad, Ved Prakash Dwivedi, Gobardhan Das
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
The adamantine derivative SQ109 induces protective pro-inflammatory cytokines and promotes Th1 and Th17-immune responses that inhibit bacterial burden in a tuberculosis mouse model.
Externí odkaz:
https://doaj.org/article/c7b5a0e17e0d49ffbc1eb9b73fc391e6
Autor:
Isha Pahuja, Kriti Negi, Anjna Kumari, Meetu Agarwal, Suparba Mukhopadhyay, Babu Mathew, Shivam Chaturvedi, Jaswinder Singh Maras, Ashima Bhaskar, Ved Prakash Dwivedi
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011165 (2023)
Stimulation of naïve T cells during primary infection or vaccination drives the differentiation and expansion of effector and memory T cells that mediate immediate and long-term protection. Despite self-reliant rescue from infection, BCG vaccination
Externí odkaz:
https://doaj.org/article/967590c0dc944bd3aa614868c04c107d