Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ved P. Pathak"'
Publikováno v:
Sultan Qaboos University Medical Journal, Vol 12, Iss 4, Pp 508-511 (2012)
Malignant melanoma is predominantly a skin disease but in rare instances it may occur at other sites. A vaginal melanoma is a rare clinical entity and the round cell type is an uncommon variant. Although the present case was clinically diagnosed as a
Externí odkaz:
https://doaj.org/article/ffdd9e9cc8d4494b9752cbe68962f801
Autor:
Chi Ching Mak, Xianchang Gong, Elena Dneprovskaia, Andrew McPherson, Ved P. Pathak, J. Hood, Binqi Zeng, Boris Klebansky, Richard M. Fine, W. Liao, Wolfgang Wrasidlo, Glenn Noronha, Joel Renick, Ningning Zhao, Y. Zhou, Kathy Barrett, Colleen Gritzen, Moorthy S. S. Palanki, Xinshan Kang, Ge Li, Ute Splittgerber, Richard M. Soll, Daniel L. Lohse, Jianguo Cao
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:5546-5550
We report the discovery and preliminary SAR studies of a series of structurally novel benzotriazine core based small molecules as inhibitors of Src kinase. To the best of our knowledge, benzotriazine template based compounds have not been reported as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c3a59d9d64cb5d6108ec85b738a7b4
https://doi.org/10.1016/j.bmcl.2006.08.035
https://doi.org/10.1016/j.bmcl.2006.08.035
Autor:
Mark B. Anderson, David R. Luthin, Rosemary Castillo, Kenna Anderes, Eugenia A. Iatsimirskaia, John M. May, K. Eric Milgram, Ved P. Pathak, Vazir Haresh N, Margaret L. Gregory, Christie Lance Christopher
Publikováno v:
Pharmaceutical Research. 19:202-208
Purpose. The expression of cytochrome P450 enzymes (CYPs) in animals and humans is under complex hormonal regulation. Chronic treatment with drugs that alter sex hormone levels such as GnRH receptor agonists or antagonists may affect the expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e0af2e5360bc267ffe8b8e87d380f1d
https://doi.org/10.1023/a:1014281018271
https://doi.org/10.1023/a:1014281018271
Autor:
Chi Ching Mak, Chun P. Chow, Glenn Noronha, Andrew McPherson, Moorthy S.S. Palanki, Joel Renick, Jianguo Cao, Ved P. Pathak, Binqi Zeng, Richard Soll, Elena Dneprovskaia
Publikováno v:
Expert opinion on drug discovery. 4(1)
Background: The synthesis of novel benzotriazine heterocycles was developed independently around the same time by Bischler, Bamberger and Arndt. Over the years, different groups have reported the synthesis of benzotriazine based compounds. Objective:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a190cdf98ee6caf68fde3595fa65cda
https://pubmed.ncbi.nlm.nih.gov/23480335
https://pubmed.ncbi.nlm.nih.gov/23480335
Autor:
Glen Noronha, Jianguo Cao, Chun Chow, Elena Dneprovskaia, Linda Hwang, Dan Lohse, Chi Ching Mak, Andrew McPherson, Richard M. Fine, Xinshan Kang, Boris Klebansky, Moorthy S.S. Palanki, Ved P. Pathak, Joel Renick, Richard Soll, Binqi Zeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53d4f3146de588732bf746c8ec5d69ab
https://doi.org/10.2174/978160805201110703010121
https://doi.org/10.2174/978160805201110703010121
Publikováno v:
Journal of Medicinal Chemistry. 37:2477-2480
The synthesis and evaluation as inhibitors of purine nucleoside phosphorylase of six 9-deazahypoxanthines (2a-f) are reported. In contrast to reports in the literature of other hypoxanthine-guanine analog pairs, these inhibitors (2a-f) are equipotent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b1d6b1b9ca3aba73b16bd5119f637b
https://doi.org/10.1021/jm00041a027
https://doi.org/10.1021/jm00041a027
Publikováno v:
Sultan Qaboos University medical journal. 12(4)
Malignant melanoma is predominantly a skin disease but in rare instances it may occur at other sites. A vaginal melanoma is a rare clinical entity and the round cell type is an uncommon variant. Although the present case was clinically diagnosed as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ce3277b02e8b3cb93b74dfd167cc03a
https://pubmed.ncbi.nlm.nih.gov/23275850
https://pubmed.ncbi.nlm.nih.gov/23275850
Autor:
Ved P. Pathak, John A. Montgomery
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 33:81-85
14C labeled 2-amino-7-(3-pyridylmethyl)-4-oxo-3H,5H-pyrrolo[3,2-d]pyrimidine(6) was synthesized starting from methyl 3-amino-4-(3-pyridylmethyl)-1H -pyrrolo-2-carboxylate. This pyrrole on condensation with 14C labeled benzoylisothiocyanate followed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c328e168ec27c4fd2e2b62b2932820d
https://doi.org/10.1002/jlcr.2580330202
https://doi.org/10.1002/jlcr.2580330202
Autor:
Ved P. Pathak
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8ace98a8c33c29c21e36f628665a6b5
https://doi.org/10.1002/chin.199322154
https://doi.org/10.1002/chin.199322154
Autor:
Elena Dneprovskaia, Daniel L. Lohse, Richard Soll, Andrew McPherson, Chi Ching Mak, John Hood, Boris Klebansky, Richard M. Fine, Joel Renick, Jianguo Cao, Chun P. Chow, Moorthy S. S. Palanki, Glenn Noronha, Ved P. Pathak, Binqi Zeng, Xinshan Kang
Publikováno v:
Current topics in medicinal chemistry. 8(10)
Chronic myelogenous leukemia (CML) is a hematological stem cell disorder caused by increased and unregulated growth of myeloid cells in the bone marrow, and the accumulation of excessive white blood cells. Abelson tyrosine kinase (ABL) is a non-recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12165fa94b4010e1abb10fefa72becb6
https://pubmed.ncbi.nlm.nih.gov/18673174
https://pubmed.ncbi.nlm.nih.gov/18673174