Norepinephrine Drives Sleep Fragmentation Activation of Asparagine Endopeptidase, Locus Ceruleus Degeneration, and Hippocampal Amyloid-β 42 Accumulation.

Autor: Zhang K; Departments of Medicine and Pharmacology, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104., Zhu Y; Departments of Medicine and Pharmacology, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104., Fenik P; Departments of Medicine and Pharmacology, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104., Fleysh D; Departments of Medicine and Pharmacology, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104., Ly C; Departments of Medicine and Pharmacology, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104., Thomas SA; Departments of Medicine and Pharmacology, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104., Veasey S; Departments of Medicine and Pharmacology, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 veasey@mail.med.upenn.edu.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2024 Jul 10; Vol. 44 (28). Date of Electronic Publication: 2024 Jul 10.

Historic building recording at Crowbridge Farm, Chappel Hill, Halstead, CO9 1JS: June 2021

Autor: Veasey, S

The record will include: " Plan form of the site " A measured survey including floor plans, elevations and sections " Photographic record accompanied by appropriate photographic register " Assessment of the building's chronological development " Deta

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Hypocretin/orexin influences chronic sleep disruption injury in the hippocampus.

Autor: Nick H; Department of Medicine and the Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania Philadelphia, Philadelphia, PA, United States., Fenik P; Department of Medicine and the Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania Philadelphia, Philadelphia, PA, United States., Zhu Y; Department of Medicine and the Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania Philadelphia, Philadelphia, PA, United States., Veasey S; Department of Medicine and the Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania Philadelphia, Philadelphia, PA, United States.

Publikováno v: Frontiers in aging neuroscience [Front Aging Neurosci] 2022 Oct 06; Vol. 14, pp. 1025402. Date of Electronic Publication: 2022 Oct 06 (Print Publication: 2022).

State of the climate in 2016

Autor: Aaron-Morrison, A. P., Ackerman, S. A., Adams, N. G., Adler, R. F., Albanil, A., Alfaro, E. J., Allan, R., Alves, L. M., Amador, J. A., Andreassen, L. M., Arendt, A., Arévalo, J., Arndt, D. S., Arzhanova, N. M., Aschan, M. M., Azorin-Molina, C., Banzon, V., Bardin, M. U., Barichivich, J., Baringer, M. O., Barreira, S., Baxter, S., Bazo, J., Becker, A., Bedka, K. M., Behrenfeld, M. J., Bell, G. D., Belmont, M., Benedetti, A., Bernhard, G., Berrisford, P., Berry, D. I., Bettolli, M. L., Bhatt, U. S., Bidegain, M., Bill, B. D., Billheimer, S., Bissolli, P., Blake, E. S., Blunden, J., Bosilovich, M. G., Boucher, O., Boudet, D., Box, J. E., Boyer, T., Braathen, G. O., Bromwich, D. H., Brown, R., Bulygina, O. N., Burgess, D., Calderón, B., Camargo, S. J., Campbell, J. D., Cappelen, J., Carrasco, G., Carter, B. R., Chambers, D. P., Chandler, E., Christiansen, H. H., Christy, J. R., Chung, D., Chung, E. S., Cinque, K., Clem, K. R., Coelho, C. A., Cogley, J. G., Coldewey-Egbers, M., Colwell, S., Cooper, O. R., Copland, L., Cosca, C. E., Cross, J. N., Crotwell, M. J., Crouch, J., Davis, S. M., Eyto, E., Jeu, R. A. M., Laat, J., Degasperi, C. L., Degenstein, D., Demircan, M., Derksen, C., Destin, D., Di Girolamo, L., Di Giuseppe, F., Diamond, H. J., Dlugokencky, E. J., Dohan, K., Dokulil, M. T., Dolgov, A. V., Dolman, A. J., Domingues, C. M., Donat, M. G., Dong, S., Dorigo, W. A., Dortch, Q., Doucette, G., Drozdov, D. S., Ducklow, H., Dunn, R. J. H., Durán-Quesada, A. M., Dutton, G. S., Ebrahim, A., Elkharrim, M., Elkins, J. W., Espinoza, J. C., Etienne-Leblanc, S., Evans, T. E., Famiglietti, J. S., Farrell, S., Fateh, S., Fausto, R. S., Fedaeff, N., Feely, R. A., Feng, Z., Fenimore, C., Fettweis, X., Fioletov, V. E., Flemming, J., Fogarty, C. T., Fogt, R. L., Folland, C., Fonseca, C., Fossheim, M., Foster, M. J., Fountain, A., Francis, S. D., Franz, B. A., Frey, R. A., Frith, S. M., Froidevaux, L., Ganter, C., Garzoli, S., Gerland, S., Gobron, N., Goldenberg, S. B., Gomez, R. S., Goni, G., Goto, A., Grooß, J. U., Gruber, A., Guard, C. C., Gugliemin, M., Gupta, S. K., Gutiérrez, J. M., Hagos, S., Hahn, S., Haimberger, L., Hakkarainen, J., Hall, B. D., Halpert, M. S., Hamlington, B. D., Hanna, E., Hansen, K., Hanssen-Bauer, I., Harris, I., Heidinger, A. K., Heikkilä, A., Heil, A., Heim, R. R., Hendricks, S., Hernández, M., Hidalgo, H. G., Hilburn, K., Ho, S. P. B., Holmes, R. M., Hu, Z. Z., Huang, B., Huelsing, H. K., Huffman, G. J., Hughes, C., Hurst, D. F., Ialongo, I., Ijampy, J. A., Ingvaldsen, R. B., Inness, A., Isaksen, K., Ishii, M., Jevrejeva, S., Jiménez, C., Jin, X., Johannesen, E., John, V., Johnsen, B., Johnson, B., Johnson, G. C., Jones, P. D., Joseph, A. C., Jumaux, G., Kabidi, K., Kaiser, J. W., Kato, S., Kazemi, A., Keller, L. M., Kendon, M., Kennedy, J., Kerr, K., Kholodov, A. L., Khoshkam, M., Killick, R., Kim, H., Kim, S. J., Kimberlain, T. B., Klotzbach, P. J., Knaff, J. A., Kobayashi, S., Kohler, J., Korhonen, J., Korshunova, N. N., Kovacs, K. M., Kramarova, N., Kratz, D. P., Kruger, A., Kruk, M. C., Kudela, R., Kumar, A., Lakatos, M., Lakkala, K., Lander, M. A., Landsea, C. W., Lankhorst, M., Lantz, K., Lazzara, M. A., Lemons, P., Leuliette, E., L’heureux, M., Lieser, J. L., Lin, I. I., Liu, H., Liu, Y., Locarnini, R., Loeb, N. G., Lo Monaco, C., Long, C. S., López Álvarez, L. A., Lorrey, A. M., Loyola, D., Lumpkin, R., Luo, J. J., Luojus, K., Lydersen, C., Lyman, J. M., Maberly, S. C., Maddux, B. C., Malheiros Ramos, A., Malkova, G. V., Manney, G., Marcellin, V., Marchenko, S. S., Marengo, J. A., Marra, J. J., Marszelewski, W., Martens, B., Martínez-Güingla, R., Massom, R. A., Mata, M. M., Mathis, J. T., May, L., Mayer, M., Mazloff, M., Mcbride, C., Mccabe, M. F., Mccarthy, M., Mcclelland, J. W., Mcgree, S., Mcvicar, T. R., Mears, C. A., Meier, W., Meinen, C. S., Mekonnen, A., Menéndez, M., Mengistu Tsidu, G., Menzel, W. P., Merchant, C. J., Meredith, M. P., Merrifield, M. A., Metzl, N., Minnis, P., Miralles, D. G., Mistelbauer, T., Mitchum, G. T., Monselesan, D., Monteiro, P., Montzka, S. A., Morice, C., Mote, T., Mudryk, L., Mühle, J., Mullan, A. B., Nash, E. R., Naveira-Garabato, A. C., Nerem, R. S., Newman, P. A., Nieto, J. J., Noetzli, J., O’neel, S., Osborn, T. J., Overland, J., Oyunjargal, L., Parinussa, R. M., Park, E. H., Parker, D., Parrington, M., Parsons, A. R., Pasch, R. J., Pascual-Ramírez, R., Paterson, A. M., Paulik, C., Pearce, P. R., Pelto, M. S., Peng, L., Perkins-Kirkpatrick, S. E., Perovich, D., Petropavlovskikh, I., Pezza, A. B., Phillips, D., Pinty, B., Pitts, M. C., Pons, M. R., Porter, A. O., Primicerio, R., Proshutinsky, A., Quegan, S., Quintana, J., Rahimzadeh, F., Rajeevan, M., Randriamarolaza, L., Razuvaev, V. N., Reagan, J., Reid, P., Reimer, C., Rémy, S., Renwick, J. A., Revadekar, J. V., Richter-Menge, J., Riffler, M., Rimmer, A., Rintoul, S., Robinson, D. A., Rodell, M., Rodríguez Solís, J. L., Romanovsky, V. E., Ronchail, J., Rosenlof, K. H., Roth, C., Rusak, J. A., Sabine, C. L., Sallée, J. B., Sánchez-Lugo, A., Santee, M. L., Sawaengphokhai, P., Sayouri, A., Scambos, T. A., Schemm, J., Schladow, S. G., Schmid, C., Schmid, M., Schmidtko, S., Schreck, C. J., Selkirk, H. B., Send, U., Sensoy, S., Setzer, A., Sharp, M., Shaw, A., Shi, L., Shiklomanov, A. I., Shiklomanov, N. I., Siegel, D. A., Signorini, S. R., Sima, F., Simmons, A. J., Smeets, C. J. P. P., Smith, S. L., Spence, J. M., Srivastava, A. K., Stackhouse, P. W., Stammerjohn, S., Steinbrecht, W., Stella, J. L., Stengel, M., Stennett-Brown, R., Stephenson, T. S., Strahan, S., Streletskiy, D. A., Sun-Mack, S., Swart, S., Sweet, W., Talley, L. D., Tamar, G., Tank, S. E., Taylor, M. A., Tedesco, M., Teubner, K., Thoman, R. L., Thompson, P., Thomson, L., Timmermans, M. L., Maxim Timofeyev, Tirnanes, J. A., Tobin, S., Trachte, K., Trainer, V. L., Tretiakov, M., Trewin, B. C., Trotman, A. R., Tschudi, M., As, D., Wal, R. S. W., A, R. J., Schalie, R., Schrier, G., Werf, G. R., Meerbeeck, C. J., Velicogna, I., Verburg, P., Vigneswaran, B., Vincent, L. A., Volkov, D., Vose, R. S., Wagner, W., Wåhlin, A., Wahr, J., Walsh, J., Wang, C., Wang, J., Wang, L., Wang, M., Wang, S. H., Wanninkhof, R., Watanabe, S., Weber, M., Weller, R. A., Weyhenmeyer, G. A., Whitewood, R., Wijffels, S. E., Wilber, A. C., Wild, J. D., Willett, K. M., Williams, M. J. M., Willie, S., Wolken, G., Wong, T., Wood, E. F., Woolway, R. I., Wouters, B., Xue, Y., Yamada, R., Yim, S. Y., Yin, X., Young, S. H., Yu, L., Zahid, H., Zambrano, E., Zhang, P., Zhao, G., Zhou, L., Ziemke, J. R., Love-Brotak, S. E., Gilbert, K., Maycock, T., Osborne, S., Sprain, M., Veasey, S. W., Ambrose, B. J., Griffin, J., Misch, D. J., Riddle, D. B., Young, T.

Publikováno v: Bulletin of the American Meteorological Society
Aaron-Morrison, A P, Ackerman, S A, Adams, N G, Adler, R F, Albanil, A, Alfaro, E J, Allan, R, Alves, L M, Amador, J A, Andreassen, L M, Arendt, A, Arévalo, J, Arndt, D S, Arzhanova, N M, Aschan, M M, Azorin-Molina, C, Banzon, V, Bardin, M U, Barichivich, J, Baringer, M O, Barreira, S, Baxter, S, Bazo, J, Becker, A, Bedka, K M, Behrenfeld, M J, Bell, G D, Belmont, M, Benedetti, A, Bernhard, G, Berrisford, P, Berry, D I, Bettolli, M L, Bhatt, U S, Bidegain, M, Bill, B D, Billheimer, S, Bissolli, P, Blake, E S, Blunden, J, Bosilovich, M G, Boucher, O, Boudet, D R, Box, J E, Boyer, T, Braathen, G O, Bromwich, D H, Brown, R, Bulygina, O N, Burgess, D, Calderón, B, Camargo, S J, Campbell, J D, Cappelen, J, Carrasco, G, Carter, B R, Chambers, D P, Chandler, E, Christiansen, H H, Christy, J R, Chung, D, Chung, E S, Cinque, K, Clem, K R, Coelho, C A, Cogley, J G, Coldewey-Egbers, M, Colwell, S, Cooper, O R, Copland, L, Cosca, C E, Cross, J N, Crotwell, M J, Crouch, J, Davis, S M, De Eyto, E, De Jeu, R A M, De Laat, J, Degasperi, C L, Degenstein, D, Demircan, M, Derksen, C, Destin, D, Di Girolamo, L, Di Giuseppe, F, Diamond, H J, Dlugokencky, E J, Dohan, K, Dokulil, M T, Dolgov, A V, Dolman, A J, Domingues, C M, Donat, M G, Dong, S, Dorigo, W A, Dortch, Q, Doucette, G, Drozdov, D S, Ducklow, H, Dunn, R J H, Durán-Quesada, A M, Dutton, G S, Ebrahim, A, Elkharrim, M, Elkins, J W, Espinoza, J C, Etienne-Leblanc, S, Evans, T E, Famiglietti, J S, Farrell, S A, Fateh, S, Fausto, R S, Fedaeff, N, Feely, R A, Feng, Z, Fenimore, C, Fettweis, X, Fioletov, V E, Flemming, J, Fogarty, C T, Fogt, R L, Folland, C, Fonseca, C, Fossheim, M, Foster, M J, Fountain, A, Francis, S D, Franz, B A, Frey, R A, Frith, S M, Froidevaux, L, Ganter, C, Garzoli, S, Gerland, S, Gobron, N, Goldenberg, S B, Gomez, R S, Goni, G J, Goto, A, Grooß, J U, Gruber, A, Guard, C C, Gugliemin, M, Gupta, S K, Gutiérrez, J M, Hagos, S, Hahn, S, Haimberger, L, Hakkarainen, J, Hall, B D, Halpert, M S, Hamlington, B D, Hanna, E, Hansen, K, Hanssen-Bauer, I, Harris, I A, Heidinger, A K, Heikkilä, A, Heil, A, Heim, R R J, Hendricks, S, Hernández, M, Hidalgo, H G, Hilburn, K, Ho, S P B, Holmes, R M, Hu, Z Z, Huang, B, Huelsing, H K, Huffman, G J, Hughes, N C, Hurst, D F, Ialongo, I, Ijampy, J A, Ingvaldsen, R B, Inness, A, Isaksen, K, Ishii, M, Jevrejeva, S, Jiménez, C, Jin, X, Johannesen, E, John, V, Borch-Johnsen, K, Johnson, B, Johnson, G C, Jones, P D, Joseph, A C, Jumaux, G, Kabidi, K, Kaiser, J W, Kato, S, Kazemi, A, Keller, L M, Kendon, M, Kennedy, J J, Kerr, K, Kholodov, A L, Khoshkam, M, Killick, R, Kim, H, Kim, S J, Kimberlain, T B, Klotzbach, P J, Knaff, J A, Kobayashi, S, Kohler, J, Korhonen, J, Korshunova, N N, Kovacs, K M, Kramarova, N, Kratz, D P, Kruger, A, Kruk, M C, Kudela, R, Kumar, A, Lakatos, M, Lakkala, K, Lander, M A, Landsea, C W, Lankhorst, M, Lantz, K, Lazzara, M A, Lemons, P, Leuliette, E, L’Heureux, M, Lieser, J L, Lin, I I, Liu, H, Liu, Y, Locarnini, R, Loeb, N G, Lo Monaco, C, Long, C S, López Álvarez, L A, Lorrey, A M, Loyola, D, Lumpkin, R, Luo, J-J, Luojus, K, Lydersen, C, Lyman, J M, Maberly, S C, Maddux, B C, Malheiros Ramos, A, Malkova, G V, Manney, G L, Marcellin, V, Marchenko, S, Marengo, J A, Marra, J J, Marszelewski, W, Martens, B, Martínez-Güingla, R, Massom, R A, Mata, M M, Mathis, J T, May, L, Mayer, M, Mazloff, M, McBride, C, McCabe, M F, McCarthy, M, McClelland, J W, McGree, S, McVicar, T R, Mears, C A, Meier, W, Meinen, C S, Mekonnen, A, Menéndez, M, Mengistu Tsidu, G, Menzel, W P, Merchant, C J, Meredith, M P, Merrifield, M A, Metzl, N, Minnis, P, Miralles, D G, Mistelbauer, T, Mitchum, G T, Monselesan, D, Monteiro, P M S, Montzka, S A, Morice, C, Mote, T, Mudryk, L, Mühle, J, Mullan, A B, Nash, E R, Naveira-Garabato, A C, Nerem, S R, Newman, P A, Nieto, J J, Noetzli, J, O’Neel, S, Osborn, T J, Overland, J, Oyunjargal, L, Parinussa, R M, Park, E H, Parker, D, Parrington, M, Parsons, A R, Pasch, R J, Pascual-Ramírez, R, Paterson, A M, Paulik, C, Pearce, P R, Pelto, M S, Peng, L, Perkins-Kirkpatrick, S E, Perovich, D, Petropavlovskikh, I, Pezza, A B, Phillips, D, Pinty, B, Pitts, M C, Pons, M R, Porter, A O, Primicerio, R, Proshutinsky, A, Quegan, S, Quintana, J, Rahimzadeh, F, Rajeevan, M, Randriamarolaza, L, Razuvaev, V N, Reagan, J R, Reid, P, Reimer, C, Rémy, S, Renwick, J A, Revadekar, J V, Richter-Menge, J, Riffler, M, Rimmer, A, Rintoul, S, Robinson, D A, Rodell, M, Rodríguez Solís, J L, Romanovsky, V E, Ronchail, J, Rosenlof, K H, Roth, C, Rusak, J A, Sabine, C L, Sallée, J B, Sánchez-Lugo, A, Santee, M L, Sawaengphokhai, P, Sayouri, A, Scambos, T A, Schemm, J, Schladow, S G, Schmid, C, Schmid, M, Schmidtko, S, Schreck, C J, Selkirk, H B, Send, U, Sensoy, S, Setzer, A, Sharp, M, Shaw, A, Shi, L, Shiklomanov, A I, Shiklomanov, N I, Siegel, D A, Signorini, S R, Sima, F, Simmons, A J, Smeets, C J P P, Smith, S L, Spence, J M, Srivastava, A K, Stackhouse, P W J, Stammerjohn, S, Steinbrecht, W, Stella, J L, Stengel, M, Stennett-Brown, R, Stephenson, T S, Strahan, S, Streletskiy, D A, Sun-Mack, S, Swart, S, Sweet, W, Talley, L D, Tamar, G, Tank, S E, Taylor, M A, Tedesco, M, Teubner, K, Thoman, R L, Thompson, P, Thomson, L, Timmermans, M L, Tirnanes, J A, Tobin, S, Trachte, K, Trainer, V L, Tretiakov, M, Trewin, B C, Trotman, A R, Tschudi, M, van As, D, van de Wal, R S W, van der A, R J, Van Der Schalie, R, Van Der Schrier, G, Van Der Werf, G R, Van Meerbeeck, C J, Velicogna, I, Verburg, P, Vigneswaran, B, Vincent, L A, Volkov, D, Vose, R S, Wagner, W, Wåhlin, A, Wahr, J, Walsh, J, Wang, C, Wang, J, Wang, L, Wang, M, Wang, S-H, Wanninkhof, R, Watanabe, S, Weber, M, Weller, R A, Weyhenmeyer, G A, Whitewood, R, Wijffels, S E, Wilber, A C, Wild, J D, Willett, K M, Williams, M J M, Willie, S, Wolken, G, Wong, T, Wood, E F, Woolway, R I, Wouters, B, Xue, Y, Yamada, R, Yim, S Y, Yin, X, Young, S H, Yu, L, Zahid, H, Zambrano, E, Zhang, P, Zhao, G, Zhou, L, Ziemke, J R, Love-Brotak, S E, Gilbert, K, Maycock, T, Osborne, S, Sprain, M, Veasey, S W, Ambrose, B J, Griffin, J, Misch, D J, Riddle, D B & Young, T 2017, ' State of the climate in 2016 ', Bulletin of the American Meteorological Society, vol. 98, no. 8, pp. Si-S280 . https://doi.org/10.1175/2017BAMSStateoftheClimate.2
Bulletin of the American Meteorological Society, 98(8), Si-S280. American Meteorological Society
Bulletin Of The American Meteorological Society (0003-0007) (Amer Meteorological Soc), 2017-08, Vol. 98, N. 8, P. S1-S277
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In 2016, the dominant greenhouse gases released into Earth's atmosphere-carbon dioxide, methane, and nitrous oxide-continued to increase and reach new record highs. The 3.5 +/- 0.1 ppm rise in global annual mean carbon dioxide from 2015 to 2016 was t

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https://ora.ox.ac.uk/objects/uuid:0f7617ce-b505-4361-b19e-611c31a7331a

Late-in-life neurodegeneration after chronic sleep loss in young adult mice.

Autor: Owen JE; Department of Medicine, Perelman School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania, USA., Zhu Y; Department of Medicine, Perelman School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania, USA., Fenik P; Department of Medicine, Perelman School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania, USA., Zhan G; Department of Medicine, Perelman School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania, USA., Bell P; Department of Medicine, Perelman School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania, USA., Liu C; Department of Medicine, Perelman School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania, USA., Veasey S; Department of Medicine, Perelman School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania, USA.

Publikováno v: Sleep [Sleep] 2021 Aug 13; Vol. 44 (8).