Výsledky vyhledávání - "Véronique Cadet-Daniel"

Hemisynthetic derivatives of the natural alkaloid trilobine are fast-acting antimalarial compounds with sustained activity in multi-drug resistant P. falciparum isolates

Malaria eradication requires the development of new drugs to combat drug-resistant parasites. The search for new chemical scaffolds that target novel pathways of the human malaria parasite Plasmodium falciparum is of highest priority. We identified b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5660d998302935d987b9c8699ee1b0ff
https://doi.org/10.1101/2022.08.30.505923

Zobrazit plný text záznamu

Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum

Publikováno v: iScience
iScience, 2023, 26 (2), pp.105940. ⟨10.1016/j.isci.2023.105940⟩

International audience; Malaria eradication requires the development of new drugs to combat drug-resistant parasites. We identified bisbenzylisoquinoline alkaloids isolated from Cocculus hirsutus that are active against Plasmodium falciparum blood st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951371418144c9b836c88ea30d6911ea
https://doi.org/10.1016/j.isci.2023.105940

Zobrazit plný text záznamu

Identification of Chemical Probes Targeting MBD2

Autor: Diane Erdmann, Jean Contreras, Rémy A. Le Meur, Bruno Vitorge, Vincent Saverat, Ambre Tafit, Corinne Jallet, Véronique Cadet-Daniel, Corentin Bon, Phannarath Phansavath, Virginie Ratovelomanana-Vidal, Albert Jeltsch, Sophie Vichier-Guerre, J. Iñaki Guijarro, Paola B. Arimondo

Publikováno v: ACS Chemical Biology
ACS Chemical Biology, 2022, Published as part of the ACS Chemical Biology special issue “Epigenetics 2022”., 17 (6), pp.1415-1426. ⟨10.1021/acschembio.1c00959⟩

International audience; Epigenetics has received much attention in the past decade. Many insights on epigenetic (dys)regulation in diseases have been obtained, and clinical therapies targeting them are in place. However, the readers of the epigenetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5acb0f8d3441c15e8b36496ba011807
https://hal-pasteur.archives-ouvertes.fr/pasteur-03688129

Zobrazit plný text záznamu

Procainamide-SAHA fused inhibitors of hHDAC6 tackle multi-drug resistant malaria parasites

Autor: Elie Hammam, Roger Peronet, Artur Scherf, Salah Mecheri, Camille Roesch, Ludovic Halby, Corentin Bon, Irina Dobrescu, Ambre Tafit, Paola B. Arimondo, Aurélie Claes, Diane Erdmann, Johanna Viluma, Véronique Cadet-Daniel, Melissa Mairet-Khedim, Benoit Witkowski, Flore Nardella

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2021, 64 (14), pp.10403-10417. ⟨10.1021/acs.jmedchem.1c00821⟩
Journal of Medicinal Chemistry, American Chemical Society, In press, ⟨10.1021/acs.jmedchem.1c00821⟩

International audience; Epigenetic post-translational modifications are essential for human malaria parasite survival and progression through its life cycle. Here, we present new functionalized suberoylanilide hydroxamic acid (SAHA) derivatives that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f5613d6b100c6ac0566df4786f8d56
https://hal.science/hal-03264653/document

Zobrazit plný text záznamu

Tuberculosis trends in a hot-spot region in Paris, France

Autor: B Audigier, Véronique Cadet-Daniel, Catherine Pierre-Audigier, Laurence Armand-Lefevre, Brigitte Gicquel, Antoine Andremont, A-K Alame-Emane, R. Ruimy, Howard Takiff, M Vray, Christophe Sola, Nathalie Grall, C Talla

Publikováno v: International Journal of Tuberculosis and Lung Disease
International Journal of Tuberculosis and Lung Disease, 2020, 24 (4), pp.428--435. ⟨10.5588/ijtld.19.0305⟩
The International Journal of Tuberculosis and Lung Disease: The Official Journal of the International Union Against Tuberculosis and Lung Disease
The International Journal of Tuberculosis and Lung Disease: The Official Journal of the International Union Against Tuberculosis and Lung Disease, 2020, 24 (4), pp.428--435. ⟨10.5588/ijtld.19.0305⟩

SETTING: Tuberculosis (TB) incidence is declining overall in France, but not in Paris where some areas remain relative hot spots for TB.OBJECTIVES: To obtain a better knowledge of local TB epidemiology in order to facilitate control measures.DESIGN:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324b03d2850dcb3f01ef4ab51ce0f36b
https://hal.science/hal-02571403

Zobrazit plný text záznamu

DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites

Autor: Salah Mecheri, Benoit Witkowski, Flore Nardella, Artur Scherf, Elie Hammam, Ludovic Halby, Roger Peronet, Didier Menard, Véronique Cadet-Daniel, Diane Erdmann, Paola B. Arimondo

Publikováno v: ACS Central Science
ACS Central Science, ACS Publications, In press, ⟨10.1021/acscentsci.9b00874⟩
ACS Central Science, 2020, 6 (1), pp.16-21. ⟨10.1021/acscentsci.9b00874⟩
ACS Central Science, Vol 6, Iss 1, Pp 16-21 (2019)
ACS Central Science, ACS Publications, 2020, 6 (1), pp.16-21. ⟨10.1021/acscentsci.9b00874⟩

Malaria is the deadliest parasitic disease affecting over 200 million people worldwide. The increasing number of treatment failures due to multi-drug-resistant parasites in South-East Asia hinders the efforts for elimination. It is thus urgent to dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd68c668eba5b8ce8c8e319f7a42410
https://hal-pasteur.archives-ouvertes.fr/pasteur-02385718

Zobrazit plný text záznamu

Fluoroquinolone and pyrazinamide resistance in multidrug-resistant tuberculosis [Short communication]

Autor: Catherine Pierre-Audigier, S Heng, C Surcouf, Brigitte Gicquel, Alan Murray, Véronique Cadet-Daniel, Amine Namouchi, Bertrand Guillard

Publikováno v: The International Journal of Tuberculosis and Lung Disease. 16:221-223

In a study performed in Cambodia, a higher number of tuberculosis (TB) strains with mutations in the pncA gene associated with pyrazinamide resistance (PZA-R) was found in fluoroquinolone-resistant (FQ-R) multidrug-resistant (MDR) strains (93%), comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec85d8a5da2e48416e777d5052d43f94
https://doi.org/10.5588/ijtld.11.0266

Zobrazit plný text záznamu

Molecular detection of fluoroquinolone-resistance in multi-drug resistant tuberculosis in Cambodia suggests low association with XDR phenotypes

Autor: Catherine Pierre-Audigier, Seiha Heng, Brigitte Gicquel, Alan Murray, Corinne Surcouf, Amine Namouchi, Véronique Cadet-Daniel, Bertrand Guillard

Publikováno v: BMC Infectious Diseases
BMC Infectious Diseases, BioMed Central, 2011, 11 (1), pp.255. ⟨10.1186/1471-2334-11-255⟩
BMC Infectious Diseases; Vol 11
BMC Infectious Diseases, 2011, 11 (1), pp.255. ⟨10.1186/1471-2334-11-255⟩
BMC Infectious Diseases, Vol 11, Iss 1, p 255 (2011)

Background Drug susceptibility testing (DST) remains an important concern for implementing treatment of MDR tuberculosis patients. Implementation of molecular tests for drug resistance identification would facilitate DST particularly in developing co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79255b94d7fed21d3b81ca0b6bc22a83
https://hal-pasteur.archives-ouvertes.fr/pasteur-00634125/document

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání