Effect of high amylose resistant starch (HAM-RS2) supplementation on biomarkers of inflammation and oxidative stress in hemodialysis patients: a randomized clinical trial

Autor: Khosroshahi, HT, Vaziri, ND, Abedi, B, Asl, BH, Ghojazadeh, M, Jing, W, Vatankhah, AM

Publikováno v: Hemodialysis international. International Symposium on Home Hemodialysis, vol 22, iss 4
Khosroshahi, HT; Vaziri, ND; Abedi, B; Asl, BH; Ghojazadeh, M; Jing, W; et al.(2018). Effect of high amylose resistant starch (HAM-RS2) supplementation on biomarkers of inflammation and oxidative stress in hemodialysis patients: a randomized clinical trial. HEMODIALYSIS INTERNATIONAL, 22(4), 492-500. doi: 10.1111/hdi.12653. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5qr8g626

INTRODUCTION:Systemic inflammation and oxidative stress play a central role in the pathogenesis of cardiovascular disease and numerous other complications of CKD. Recent studies demonstrated that consumption of a diet enriched with amylose (HAM-RS2),

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Inverse Association Between Serum Non-High-Density Lipoprotein Cholesterol Levels and Mortality in Patients Undergoing Incident Hemodialysis

Autor: Chang, TI, Streja, E, Ko, GJ, Naderi, N, Rhee, CM, Kovesdy, CP, Kashyap, ML, Vaziri, ND, Kalantar-Zadeh, K, Moradi, H

Publikováno v: Journal of the American Heart Association, vol 7, iss 12
Chang, TI; Streja, E; Ko, GJ; Naderi, N; Rhee, CM; Kovesdy, CP; et al.(2018). Inverse Association Between Serum Non-High-Density Lipoprotein Cholesterol Levels and Mortality in Patients Undergoing Incident Hemodialysis.. Journal of the American Heart Association, 7(12). doi: 10.1161/jaha.118.009096. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/36h8x9zz

BackgroundThere is accumulating evidence that serum levels of non-high-density lipoprotein cholesterol (non-HDL-C) are a more accurate predictor of cardiovascular outcomes when compared with low-density lipoprotein cholesterol. However, we recently f

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The nature, consequences, and management of neurological disorders in chronic kidney disease

Autor: Jabbari, B, Vaziri, ND

Publikováno v: Hemodialysis international. International Symposium on Home Hemodialysis, vol 22, iss 2
Jabbari, B; & Vaziri, ND. (2018). The nature, consequences, and management of neurological disorders in chronic kidney disease. HEMODIALYSIS INTERNATIONAL, 22(2), 150-160. doi: 10.1111/hdi.12587. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9m15w92x

Perhaps no other organ in the body is affected as often and in as many ways as the brain is in patients with chronic kidney disease (CKD). Several factors contribute to the neurological disorders in CKD including accumulation of uremic toxins, metabo

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Uremia induces upregulation of cerebral tissue oxidative/inflammatory cascade, down-regulation of Nrf2 pathway and disruption of blood brain barrier

Autor: Jing, W, Jabbari, B, Vaziri, ND

Publikováno v: American journal of translational research, vol 10, iss 7
Jing, W; Jabbari, B; & Vaziri, ND. (2018). Uremia induces upregulation of cerebral tissue oxidative/inflammatory cascade, down-regulation of Nrf2 pathway and disruption of blood brain barrier. AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 10(7), 2137-2147. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9qv048rm

Chronic kidney disease (CKD) results in various central nervous systems (CNS) disorders including cognitive dysfunction, depression, anxiety, movement disorders, seizures and encephalopathy. Uremic retention products, oxidative stress, inflammation a

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Role of RAS/Wnt/beta-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy

Autor: Chen, L, Chen, D-Q, Wang, M, Liu, D, Chen, H, Dou, F, Vaziri, ND, Zhao, Y-Y

Publikováno v: Chen, L; Chen, D-Q; Wang, M; Liu, D; Chen, H; Dou, F; et al.(2017). Role of RAS/Wnt/beta-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy. CHEMICO-BIOLOGICAL INTERACTIONS, 273, 56-72. doi: 10.1016/j.cbi.2017.05.025. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4p50b7dw

Renin-angiotensin system (RAS) plays a key role in the development and progression of chronic kidney disease (CKD). Recent studies have demonstrated activation of Wnt/β-catenin pathway by RAS in CKD. However, the underlying mechanisms of RAS and Wnt

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