Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vaughn M. Gehle"'
Publikováno v:
Alcoholism: Clinical and Experimental Research. 25:1699-1707
Background: In previous studies, genetic correlations were observed between hypnotic sensitivity to ethanol and high-affinity neurotensin receptor (NTS1) binding. Provisional quantitative trait loci (QTLs) were identified for these traits, and some o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0acbd2cded162f5f0298d6edfb48393c
https://doi.org/10.1111/j.1530-0277.2001.tb02178.x
https://doi.org/10.1111/j.1530-0277.2001.tb02178.x
Autor:
Vaughn M. Gehle, V G Erwin
Publikováno v:
Alcoholism: Clinical and Experimental Research. 24:579-587
Background: It has been proposed that development of tolerance to the behavioral effects of ethanol depends on the degree of impairment produced by the drug; that is, more sensitive individuals should develop greater tolerance. Tests of this hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76edfd831bb1b8e140fdec824fdbdba9
https://doi.org/10.1111/j.1530-0277.2000.tb02028.x
https://doi.org/10.1111/j.1530-0277.2000.tb02028.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:1721-1729
Background Law doses of the N-methyl-D-aspartate receptor (NMDAR) antagonist MK-801 (dizocilpine) or ethanol increase locomotor activity to a lesser extent in long-sleep (LS), than in short-sleep (SS), mice. LS mice also have fewer brain (3H]MK-801 b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de4a6eff23e3ca519d4d897c024284a
https://doi.org/10.1111/j.1530-0277.1999.tb04066.x
https://doi.org/10.1111/j.1530-0277.1999.tb04066.x
Autor:
Vaughn M. Gehle, V. Gene Erwin
Publikováno v:
Alcoholism: Clinical and Experimental Research. 22:401-408
The C57BL/6, DBA/2, and recombinant inbred (RI) strains derived from them (BxD Rls) are the most frequently studied mouse strains with regard to genetic regulation of voluntary ethanol consumption (VEC). We have studied VEC in an alternate genetic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab6af3cddb194108f3de3f741288cde
https://doi.org/10.1111/j.1530-0277.1998.tb03666.x
https://doi.org/10.1111/j.1530-0277.1998.tb03666.x
Autor:
Katumi Sumikawa, Vaughn M. Gehle
Publikováno v:
Journal of Biological Chemistry. 267:6286-6290
Each subunit of the nicotinic acetylcholine receptor (AChR) contains two conserved cysteine residues, which are known to form a disulfide bond, in the N-terminal extracellular domain. The role of this retained structural feature in the biogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c5a3a5f8dc32eceadf1d2504f4714b6
https://doi.org/10.1016/s0021-9258(18)42693-2
https://doi.org/10.1016/s0021-9258(18)42693-2
Autor:
Katumi Sumikawa, Vaughn M. Gehle
Publikováno v:
Molecular Brain Research. 11:17-25
The role of the conserved N-glycosylation site on each subunit of the Torpedo acetylcholine receptor (AChR) in the biogenesis and function of the receptor was examined by expressing site-directed mutant subunits in Xenopus oocytes. Different mutant s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d16db48a67e7f97209cde80338199b3
https://doi.org/10.1016/0169-328x(91)90016-q
https://doi.org/10.1016/0169-328x(91)90016-q
Publikováno v:
Brain research. Molecular brain research. 45(2)
The role of the conserved carbohydrate moiety in the expression of complete acetylcholine receptor (AChR), alpha2 beta gamma delta was re-investigated by expressing additional site-directed mutant subunits, lacking an N-glycosylation site, in Xenopus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68dea6da046be6fd92998f452cf5a6b1
https://pubmed.ncbi.nlm.nih.gov/9149096
https://pubmed.ncbi.nlm.nih.gov/9149096
Publikováno v:
Brain research. Molecular brain research. 21(1-2)
The nicotinic acetylcholine receptors (AChRs) from Torpedo electric organ and mouse muscles when expressed in Xenopus oocytes desensitize with different time courses. Initially, the role of cAMP-dependent phosphorylation on the γ subunits in the dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7839869bfc1224c62c03ef51e12c545a
https://pubmed.ncbi.nlm.nih.gov/8164527
https://pubmed.ncbi.nlm.nih.gov/8164527
Publikováno v:
Alcoholism: Clinical & Experimental Research. 23:1721
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a528b025a3e02f41c3230efe8701bf31
https://doi.org/10.1097/00000374-199911000-00003
https://doi.org/10.1097/00000374-199911000-00003