Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Vathany Kulasingam"'
Publikováno v:
Bone Reports, Vol 20, Iss , Pp 101737- (2024)
Pentosidine (PEN) is an Advanced Glycation End-product (AGE) that is known to accumulate in bone collagen with aging and contribute to fracture risk. The PEN content in bone is correlated with serum PEN, making it an attractive, potential osteoporosi
Externí odkaz:
https://doaj.org/article/8680c46fed064839891147bc5b1c35ba
Publikováno v:
Metabolites, Vol 14, Iss 4, p 200 (2024)
As end-products of the intersection between the genome and environmental influences, metabolites represent a promising approach to the discovery of novel biomarkers for diseases. However, many potential biomarker candidates identified by metabolomics
Externí odkaz:
https://doaj.org/article/e79770b9c8cd4b1181c291b61495e2c2
Autor:
Pavlina Spiliopoulou, Helena J. Janse van Rensburg, Lisa Avery, Vathany Kulasingam, Albiruni Razak, Philippe Bedard, Aaron Hansen, Andrzej Chruscinski, Ben Wang, Maria Kulikova, Rachel Chen, Vanessa Speers, Alisa Nguyen, Jasmine Lee, Bryan Coburn, Anna Spreafico, Lillian L. Siu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Despite more than 2 years having elapsed since the onset of SARS-CoV-2 pandemic, a level of hesitation around increased SARS-CoV-2 vaccine toxicity in cancer patients receiving immunotherapy (IO) remains. This hesitation stems from the idea
Externí odkaz:
https://doaj.org/article/b17872c511a140019f69a96a17a53131
Autor:
Victor H. Ferreira, Javier T. Solera, Queenie Hu, Victoria G. Hall, Berta G. Arbol, W. Rod Hardy, Reuben Samson, Tina Marinelli, Matthew Ierullo, Avneet Kaur Virk, Alexandra Kurtesi, Faranak Mavandadnejad, Beata Majchrzak-Kita, Vathany Kulasingam, Anne-Claude Gingras, Deepali Kumar, Atul Humar
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Immunocompromised individuals are predisposed to severe SARS-CoV-2 infection, with transplant recipients typically displaying impaired immune response to pathogens, due to typical life-long immunosuppressive treatment. In this work, the authors evalu
Externí odkaz:
https://doaj.org/article/9fad6f00c4f145a2b068a68d5f6b0a55
Autor:
Hani Choksi, Shenghan Li, Nikita Looby, Max Kotlyar, Igor Jurisica, Vathany Kulasingam, Vinod Chandran
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15299 (2023)
Psoriatic arthritis (PsA) is a chronic, systemic, immune-mediated inflammatory disease causing cutaneous and musculoskeletal inflammation that affects 25% of patients with psoriasis. Current methods for evaluating PsA disease activity are not accurat
Externí odkaz:
https://doaj.org/article/f05329ea838e468fb30912107f06922d
Publikováno v:
Metabolites, Vol 13, Iss 8, p 963 (2023)
Approximately 25% of psoriasis patients have an inflammatory arthritis termed psoriatic arthritis (PsA). There is strong interest in identifying and validating biomarkers that can accurately and reliably predict conversion from psoriasis to PsA using
Externí odkaz:
https://doaj.org/article/4b2dda6e2b5244f088bc3b630c4d0861
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Epithelial ovarian cancer (EOC) is the most common cause of death from gynecological cancer. The outcomes of EOC are complicated, as it is often diagnosed late and comprises several heterogenous subtypes. As such, upfront treatment can be hi
Externí odkaz:
https://doaj.org/article/341dfd9c3f7b4eae802b5541e5c42ac7
Autor:
Annie Ren, Ioannis Prassas, Vijithan Sugumar, Antoninus Soosaipillai, Marcus Bernardini, Eleftherios P Diamandis, Vathany Kulasingam
Publikováno v:
F1000Research, Vol 10 (2021)
Background: In this pilot study, we perform a preliminary comparison of two targeted multiplex proteomics technologies for discerning serum protein concentration changes that may correlate to tumor burden in ovarian cancer (OC) patients. Methods: Usi
Externí odkaz:
https://doaj.org/article/045f91375fa54c209514b1ea178c2d6f
Autor:
Victor H Ferreira, Andrzej Chruscinski, Vathany Kulasingam, Trevor J Pugh, Tamara Dus, Brad Wouters, Amit Oza, Matthew Ierullo, Terrance Ku, Beata Majchrzak-Kita, Sonika T Humar, Ilona Bahinskaya, Natalia Pinzon, Jianhua Zhang, Lawrence E Heisler, Paul M Krzyzanowski, Bernard Lam, Ilinca M Lungu, Dorin Manase, Krista M Pace, Pouria Mashouri, Michael Brudno, Michael Garrels, Tony Mazzulli, Myron Cybulsky, Atul Humar, Deepali Kumar
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247258 (2021)
Health care workers (HCWs) are at higher risk for SARS-CoV-2 infection and may play a role in transmitting the infection to vulnerable patients and members of the community. This is particularly worrisome in the context of asymptomatic infection. We
Externí odkaz:
https://doaj.org/article/296e0a64cbd94bcf97642f459073385f
Autor:
Annie He Ren, Ioannis Prassas, Antoninus Soosaipillai, Stephanie Jarvi, Steven Gallinger, Vathany Kulasingam, Eleftherios P. Diamandis
Publikováno v:
F1000Research, Vol 9 (2020)
Background: To account for cancer heterogeneity, we previously introduced the concept of “personalized” tumor markers, which are biomarkers that are informative in subsets of patients or even a single patient. Recent developments in various multi
Externí odkaz:
https://doaj.org/article/4355624a13874d95ab5920e432da52e2