Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Vasyl Sava"'
Autor:
Shijie Song M.D., Xiaoyung Kong, Vasyl Sava, Chuanhai Cao, Sandra Acosta, Cesar Borlongan, Juan Sanchez-Ramos Ph.D., M.D.
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Targeted microlesions of the hippocampus have been reported to enhance neurogenesis in the subgranular zone (SGZ). The potential therapeutic impact of transient insertion of a microneedle was investigated in a mouse model of Alzheimer's disease (AD).
Externí odkaz:
https://doaj.org/article/26a8daf3a3cd40eaae08ef2ffb124c81
Autor:
Shijie Song, Xiaoyuan Kong, Sandra Acosta, Vasyl Sava, Cesar V. Borlongan, Juan Sanchez-Ramos
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 7, p 1418 (2017)
Administration of the hematopoietic growth factor granulocyte-colony stimulating Factor (G-CSF) has been reported to enhance recovery from controlled cortical impact (CCI) in rodent models. G-CSF exerts actions in both the periphery (stimulation of h
Externí odkaz:
https://doaj.org/article/571e8f4b101c4eafbe459c0bd2d8c66d
Autor:
Shijie Song, Shuojing Song, Chuanhai Cao, Xiaoyang Lin, Kunyu Li, Vasyl Sava, Juan Sanchez-Ramos
Publikováno v:
Stem Cells International, Vol 2013 (2013)
We tested the hypothesis that transient microinjury to the brain elicits cellular and humoral responses that stimulate hippocampal neurogenesis. Brief stereotaxic insertion and removal of a microneedle into the right hippocampus resulted in (a) signi
Externí odkaz:
https://doaj.org/article/4b3a43b5372b488ea63927edafc4421b
Publikováno v:
Nanomedicine (Lond)
Background: Nanocarriers loaded with siRNA can be administered intranasally to provide a noninvasive, safe alternative to direct intracerebral or intrathecal infusions. Dual-function nanocarriers can also be designed to deliver several payloads that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866ab0f31534cbfed5b92ab7055cf0f1
https://pubmed.ncbi.nlm.nih.gov/35373577
https://pubmed.ncbi.nlm.nih.gov/35373577
Publikováno v:
Cannabis Cannabinoid Res
Introduction: Treatment of traumatic brain injury (TBI) with granulocyte colony-stimulating factor (G-CSF) has been shown to enhance brain repair by direct neurotrophic actions on neural cells and by modulating the inflammatory response. Administrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed0eb2878248a9a9988a135b73a0a28
https://pubmed.ncbi.nlm.nih.gov/33614952
https://pubmed.ncbi.nlm.nih.gov/33614952
Autor:
Shijie Song, Xiaoyuan Kong, Anastasia Khvorova, William Dominguez-Viqueria, Neil Aronin, Reka A. Haraszti, Juan Sanchez-Ramos, Vasyl Sava, Parastou Foroutan, Shyam S. Mohapatra, Gary V. Martinez, Subhra Mohapatra
Publikováno v:
Journal of Drug Delivery Science and Technology. 43:453-460
The overall objective of the present research was to develop a nanocarrier system for non-invasive delivery to brain of molecules useful for gene therapy. Manganese-containing nanoparticles (mNPs) carrying anti-eGFP siRNA were tested in cell cultures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6acbf918c6aa083430eadcb6059b03
https://doi.org/10.1016/j.jddst.2017.11.013
https://doi.org/10.1016/j.jddst.2017.11.013
Publikováno v:
J Drug Deliv Sci Technol
This report describes the kinetics of Huntington's Disease (HD) gene (HTT) lowering in brains of YAC 128 mice. Lowering (or “knock-down”) of HTT mRNA expression was achieved by intranasal administration of specially designed siRNA loaded into chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498ebe973d70d491e62c053334e816bb
https://doi.org/10.1016/j.jddst.2021.102517
https://doi.org/10.1016/j.jddst.2021.102517
Publikováno v:
Data in Brief
Data on preparation and characterization of chitosan-based nanoparticles (NP) carrying small interfering RNA (siRNA) for non-invasive gene therapy is presented. Polyelectrolyte complexation method was carried out in diluted concentrations to obtain r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84ff571042374a46b12cfdda54ae0e3
https://pubmed.ncbi.nlm.nih.gov/31970274
https://pubmed.ncbi.nlm.nih.gov/31970274
Publikováno v:
Nanomedicinenanoscience research. 2(6)
Gene therapy delivery systems that rely on synthetic nanocarriers can be optimized by assays of nucleic acid protection and kinetic studies of nucleic acid release. These empirical measurements ensure nanoparticle stability and predict potential in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7464c32ab5dee1351a58252d40d2d243
https://pubmed.ncbi.nlm.nih.gov/31058264
https://pubmed.ncbi.nlm.nih.gov/31058264
Autor:
Shijie Song, Xiaoyuan Kong, Vasyl Sava, Cesar V. Borlongan, Sandra Acosta, Juan Sanchez-Ramos
Publikováno v:
Journal of Neuroscience Research. 94:409-423
Hematopoietic growth factors such as granulocyte colony-stimulating factor (G-CSF) represent a novel approach for treatment of traumatic brain injury (TBI). After mild controlled cortical impact (CCI), mice were treated with G-CSF (100 μg/kg) for 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61b100ee80084cd724863dfdb6625bca
https://doi.org/10.1002/jnr.23714
https://doi.org/10.1002/jnr.23714