Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Vasyl M. Sava"'
Publikováno v:
International Journal of Food Science & Technology. 43:261-269
Summary The suppressive effects of Camellia sinensis tea melanin (CSTM) on transformation of aryl hydrocarbon receptor (AhR) induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) were disclosed for the first time. CSTM strongly inhibited TCDD-induced
Publikováno v:
Journal of Agricultural and Food Chemistry. 52:5284-5289
The preventive effect of Thea sinensis melanin (TSM) against overdoses of N-acetyl-p-aminophenol (NAPAP) was studied on ICR mice. Animals were given 400 mg/kg intraperitoneally (i.p.) of NAPAP, and TSM was injected i.p. in doses 10-40 mg/kg 2 h befor
Autor:
T. A. Voronina, G. E. Kolodeev, G. M. Molodavkin, S. A. Andronati, S. G. Soboleva, S. Yu. Makan, Vasyl M. Sava
Publikováno v:
Pharmaceutical Chemistry Journal. 37:15-18
Established in the late 1980s, the important role of 5-HT1A receptors in the pathogenesis of anxiety states and depressions has stimulated extensive search for the corresponding selective ligands. Among the known compounds possessing a high affinity
Autor:
G. S. Huang, Svetlana Yu. Makan, Meng Yen Hong, Vasyl M. Sava, Yao Ching Hung, Tzong Hsing Jerry Chen
Publikováno v:
Food Chemistry. 78:233-240
The antioxidant activity of tea melanin (TM) derived from tea leaves was studied. The influence of TM on the kinetics of the free-radical oxidation of β-carotene revealed essential differences between their oxidative states. The reduced preparation
Publikováno v:
Journal of Ethnopharmacology. 79:75-79
Melanin was extracted from tea leaves (Thea sinensis Linn.) for the first time. Characterization of melanin proved similarity of the original compound to standard melanin. The Langmuir adsorption isotherms for gadolinium (Gd) binding were obtained us
Publikováno v:
Food Research International. 35:619-626
The protective activity of melanin-like pigment (MLP) derived from tea was studied using benzidine (BZ) as a DNA-reactive chemical. A wild strain of Drosophila melanogaster, Canton-S, was used to evaluate the toxic effect of BZ and protective power o
Publikováno v:
Food Chemistry. 73:177-184
The dark brown pigments derived from tea and tea polyphenols were studied. Physical and chemical properties revealed that pigments directly extracted from tea leaves and derived from tea polyphenols were similar to typical melanins. Further investiga
Autor:
A. S. Yavorskii, T. A. Voronina, S. A. Andronati, S. Yu. Makan, L. N. Yakubovskaya, Vasyl M. Sava, K. S. Andronati
Publikováno v:
Neurophysiology. 26:217-220
A metabolite of the anxiolytic, anticonvulsant, and soporific drug phenazepam, 3-oxyphenazepam (3-OPh), possesses strong anxiolytic action. In the present work, 3-OPh and its acetic, benzoic, nicotinic, hemisuccinic, hemiglutaric, and valproic esters
Autor:
Sergei A. Andronati, L. N. Yakubovskaya, D. P. Neshchadin, S. Yu. Makan, K. S. Andronati, Vasyl M. Sava
Publikováno v:
Pharmaceutical Chemistry Journal. 32:513-515
Publikováno v:
Biologicalpharmaceutical bulletin. 29(11)
We examined the protective ability of tea melanin against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced toxicity in C57BL6J mice. Reduced tea melanin (RTM) and non-reduced tea melanin (NRTM) were incorporated to distinguish anti-oxidant activity