Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Vasyl Eisenberg"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Tumors can employ different mechanisms to evade immune surveillance and function. Overexpression of co-inhibitory ligands that bind to checkpoint molecules on the surface of T-cells can greatly impair the function of latter. TIGIT
Externí odkaz:
https://doaj.org/article/c00d8c0f9e2c4f82ac143f6dbdeaf8b4
Autor:
Vasyl Eisenberg, Katerina Shamalov, Shimrit Meir, Shiran Hoogi, Rhitajit Sarkar, Shirel Pinker, Gal Markel, Angel Porgador, Cyrille J. Cohen
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Recent developments in cancer treatment are demonstrating the increasing and powerful potential of immunotherapeutic strategies. In this regard, the adoptive transfer of tumor-specific T-lymphocytes approaches can lead to tumor regression in cancer p
Externí odkaz:
https://doaj.org/article/7cca5c9aebaf41c5811fa65894aefc1e
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Background Tumors can employ different mechanisms to evade immune surveillance and function. Overexpression of co-inhibitory ligands that bind to checkpoint molecules on the surface of T-cells can greatly impair the function of latter. TIGIT (T cell
Publikováno v:
Advanced drug delivery reviews. 141
The last decade will be remembered as the dawn of the immunotherapy era during which we have witnessed the approval by regulatory agencies of genetically engineered CAR T-cells and of checkpoint inhibitors for cancer treatment. Understandably, T-lymp
Autor:
Dietmar Zehn, Francesca Alfei, Mauro Delorenzi, Madlaina von Hoesslin, Dirk Wohlleber, Percy A. Knolle, Benjamin Youngblood, Daniel T. Utzschneider, Cyrille J. Cohen, Hazem E. Ghoneim, Robert Thimme, Kristiyan Kanev, Maike Hofmann, Jolie G. Cullen, Vasyl Eisenberg, Yiping Fan, Patrick Roelli, Ming Wu, Doron Merkler, Katja Steiger
Publikováno v:
Nature, Vol. 571, No 7764 (2019) pp. 265-269
Nature
Nature
Cytotoxic T cells are essential mediators of protective immunity to viral infection and malignant tumours and are a key target of immunotherapy approaches. However, prolonged exposure to cognate antigens often attenuates the effector capacity of T ce
Autor:
Shiran Hoogi, Cyrille J. Cohen, Vasyl Eisenberg, Shirel Pinker, Angel Porgador, Rhitajit Sarkar, Gal Markel, Shimrit Meir, Katerina Shamalov
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in Immunology
Recent developments in cancer treatment are demonstrating the increasing and powerful potential of immunotherapeutic strategies. In this regard, the adoptive transfer of tumor-specific T-lymphocytes approaches can lead to tumor regression in cancer p