Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Vasvi Tripathi"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2307 (2023)
Neuroblastoma is among the most common childhood cancers. Neuroblastoma in advanced stages is one of the most intractable pediatric cancers, notwithstanding the recent therapeutic advances. ALK mutations are among the leading cause of hereditary neur
Externí odkaz:
https://doaj.org/article/343b173b93c444cfb2d41a4c4a93bef9
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Viruses interact with the host cellular pathways to optimize cellular conditions for replication. The Human Cytomegalovirus (HCMV) Immediate-Early protein 1 (IE1) is the first viral protein to express during infection. It is a multifunctional and con
Externí odkaz:
https://doaj.org/article/afb966e080a242ffaa5ec9372189c8ec
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186622 (2017)
SUMO proteins are important post-translational modifiers involved in multiple cellular pathways in eukaryotes, especially during the different developmental stages in multicellular organisms. The nematode C. elegans is a well known model system for s
Externí odkaz:
https://doaj.org/article/30a7db66f5a742d6a633a50a6c77e05f
Publikováno v:
Chemical Communications. 56:6735-6738
The covalent conjugation of ubiquitin (Ub), known as ubiquitination, is a multi-step reaction involving multiple enzymes. We report a real-time, tag-free method to monitor protein ubiquitination by NMR spectroscopy under physiological conditions. The
Publikováno v:
J Biol Chem
Many viral factors manipulate the host post-translational modification (PTM) machinery for efficient viral replication. In particular, phosphorylation and SUMOylation can distinctly regulate the activity of the human cytomegalovirus (HCMV) transactiv
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Viruses interact with the host cellular pathways to optimize cellular conditions for replication. The Human Cytomegalovirus (HCMV) Immediate-Early protein 1 (IE1) is the first viral protein to express during infection. It is a multifunctional and con
Autor:
Ranabir Das, Vasvi Tripathi
Publikováno v:
Current protocols in protein scienceLiterature Cited. 101(1)
The small ubiquitin-like modifier (SUMO) is an important post-translational modifier that regulates various cellular processes. Extensive investigations have been made to comprehend the enzymatic process and consequence of SUMOylation. In vitro SUMOy
Autor:
Vasvi Tripathi, D.S.S. Hembram, Ranabir Das, Hitendra Negi, D. Shet, Poulomi Biswas, Vikas Kumar, Lokesh Bhushan
When the herpes simplex virus (HSV) genome enters the nucleus for replication and transcription, phase-segregated nuclear protein bodies called Promyelocytic leukemia protein nuclear bodies (PML NBs) colocalize with the genome and repress it. HSV enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2549a27d8ad7130583c398aff4af4af
https://doi.org/10.1101/709485
https://doi.org/10.1101/709485
Aromatic amino acids buried at a protein's core are often involved in mutual paired interactions. Ab initio energy calculations have highlighted that the conformational orientations and the effects of substitutions are important for stable aromatic i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1dd16703902086b21f502004a57fc2
https://europepmc.org/articles/PMC6497963/
https://europepmc.org/articles/PMC6497963/
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186622 (2017)
PLoS ONE
PLoS ONE
SUMO proteins are important post-translational modifiers involved in multiple cellular pathways in eukaryotes, especially during the different developmental stages in multicellular organisms. The nematode C. elegans is a well known model system for s