Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vasudha Tandon"'
Autor:
Ruturajsinh M. Vala, Vasudha Tandon, Lynden G. Nicely, Luxia Guo, Yanlong Gu, Sourav Banerjee, Hitendra M. Patel
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 2549-2561 (2022)
A series of N-(4-chlorophenyl) substituted pyrano[2,3-c]pyrazoles was synthesised and screened for their potential to inhibit kinases and exhibit anticancer activity against primary patient-derived glioblastoma 2D cells and 3D neurospheres. A collect
Externí odkaz:
https://doaj.org/article/50ae6339b0b74d54bcfdd2363b0342d3
Autor:
Vasudha Tandon, Rita Moreno, Kira Allmeroth, Jean Quinn, Sandra E. Wiley, Lynden G. Nicely, Martin S. Denzel, Joanne Edwards, Laureano de la Vega, Sourav Banerjee
Publikováno v:
Biosci Rep.
Preserving proteostasis is a major survival mechanism for cancer. Dual specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) is a key oncogenic kinase that directly activates the transcription factor heat-shock factor 1 (HSF1) and the 26S p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c2db095d9e03c1e0cfaadaa653e515
https://hdl.handle.net/21.11116/0000-000C-969A-D21.11116/0000-000C-969C-B
https://hdl.handle.net/21.11116/0000-000C-969A-D21.11116/0000-000C-969C-B
Autor:
Ruturajsinh M, Vala, Vasudha, Tandon, Lynden G, Nicely, Luxia, Guo, Yanlong, Gu, Sourav, Banerjee, Hitendra M, Patel
Publikováno v:
Annals of medicine. 54(1)
A series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43380ed2cbb236cab93b25844c230747
https://pubmed.ncbi.nlm.nih.gov/36120909
https://pubmed.ncbi.nlm.nih.gov/36120909
Autor:
Mohammad, Ashraf, Hassan, Ismahel, Sytske, Lub, Eilidh, Middleton, Attika, Chaudhary, Ameerah, Gardee, Laulwa Al, Salloum, Eva, Szilagyi-Nagy, Rachel, Wales, Samia, Omar, Tracey Anne, Baird, Roddy, O'Kane, John, Holden, Mohamed, Abdelsadg, Pierce, Burr, Antony Ben, Decruz, Khaled, Badran, Anthony, Amato-Watkins, Likhith, Alakandy, Rosie, Boardman, Lynden, Nicely, Vasudha, Tandon, Sourav, Banerjee, Andrew, Keenlyside, Mark, Hughes, Jen Wae, Ho, Jake, Sieradzki, Elizabeth Phuong My, Phan, Niall John James, MacDougall, Aneesah Bashir Binti Azad, Bashir, Dana L, Hutton, Alexander S F, Doley, Krishna K, Oochit, Georgios, Kontorinis, Yun Yang, Wong
Publikováno v:
Surgical neurology international. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e0bda3db6dfa5a88d97ee69f4ca0aa
https://pubmed.ncbi.nlm.nih.gov/35509535
https://pubmed.ncbi.nlm.nih.gov/35509535
Autor:
Vasudha Tandon, Ruturajsinh M. Vala, Albert Chen, Robert L. Sah, Hitendra M. Patel, Michael C. Pirrung, Sourav Banerjee
Publikováno v:
Bioscience reports. 42(2)
Proteasome-addicted neoplastic malignancies present a considerable refractory and relapsed phenotype with patients exhibiting drug resistance and high mortality rates. To counter this global problem, novel proteasome-based therapies are being develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40045b9da1c0deb4e9b90f9a07462935
https://pubmed.ncbi.nlm.nih.gov/35088066
https://pubmed.ncbi.nlm.nih.gov/35088066
Autor:
Michael C. Pirrung, Ruturajsinh M. Vala, Vasudha Tandon, Albert Chen, Robert L. Sah, Sourav Banerjee, Hitendra M. Patel
Proteasome-addicted neoplastic malignancies present a considerable refractory and relapsed phenotype with patients exhibiting drug-resistance and high mortality rates. To counter this global problem, novel proteasome-based therapies are being develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f1bf820b26384f6734795162859a78
https://doi.org/10.1101/2021.10.27.466109
https://doi.org/10.1101/2021.10.27.466109
Autor:
Hitendra M Patel, Sourav Banerjee, Yanlong Gu, Luxia Guo, Lynden G Nicely, Vasudha Tandon, Ruturajsinh M. Vala
A series of novel pyrano[2,3-c]pyrazoles were synthesized and screened for their potential to inhibit kinases and exhibit anti-cancer activity against primary patient derived glioblastoma 2D cells and 3D neurospheres. A collection of 10 compounds wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b6aa0c00aef7b779a572afb948dc53e
https://doi.org/10.26434/chemrxiv.14774835
https://doi.org/10.26434/chemrxiv.14774835
Publikováno v:
The Journal of Biological Chemistry
Over the last decade, the CMGC kinase DYRK2 has been reported as a tumor suppressor across various cancers triggering major antitumor and proapoptotic signals in breast, colon, liver, ovary, brain, and lung cancers, with lower DYRK2 expression correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061eea48deade93ca0fc9f31e939d4a2
http://europepmc.org/articles/PMC7948649
http://europepmc.org/articles/PMC7948649
Autor:
Jenna J Lee, Haydee L. Gutierrez, Sourav Banerjee, Junyu Xiao, Liang Ruqi, Sandra E. Wiley, Vasudha Tandon, Tiantian Wei, Jue Wang, Kimberly L. Cooper, Lukas Chavez, Edwin F. Juarez, Xiaoguang Lei, Caitlin Costello, Jack E. Dixon, Owen Chapman, Laureano de la Vega, Jill P. Mesirov, Robert L. Sah, Joshua E. Mayfield
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 49
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Multiple myeloma (MM) and triple-negative breast cancer (TNBC) are dependent on 26S proteasome for malignancy. We have previously shown that the proteasome-regulating kinase DYRK2 is a viable target for both MM and TNBC. Here we identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7db7d51ffd9e6896fe3714cfa965dda
https://escholarship.org/uc/item/10h2v4tz
https://escholarship.org/uc/item/10h2v4tz