Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Vasudevan Seshadri"'
Autor:
Jatin Behari, Pranita Borkar, Arya Vindu, Vishal Dandewad, Sindhuri Upadrasta, Dhanasekaran Shanmugam, Vasudevan Seshadri
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Plasmodium falciparum is a causative agent for malaria and has a complex life cycle in human and mosquito hosts. During its life cycle, the malarial parasite Plasmodium goes through different asexual and sexual stages, in humans and mosquitoes. Expre
Externí odkaz:
https://doaj.org/article/fd531e6ae4fe43349ee7e55ff824b99f
Autor:
Rajesh Kumar Manne, Yashika Agrawal, Anil Bargale, Asha Patel, Debasish Paul, Neha Anilkumar Gupta, Srikanth Rapole, Vasudevan Seshadri, Deepa Subramanyam, Praveenkumar Shetty, Manas Kumar Santra
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 6, Pp 483-495 (2017)
The transformation of a normal cell to cancer requires the derail of multiple pathways. Normal signaling in a cell is regulated at multiple stages by the presence of feedback loops, calibration of levels of proteins by their regulated turnover, and p
Externí odkaz:
https://doaj.org/article/59eeeb538db6432a893b33f9a2130b06
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Type 2 diabetes mellitus (T2DM) is no more a lifestyle disease of developed countries. It has emerged as a major health problem worldwide including developing countries. However, how diabetes could be detected at an early stage (prediabetes) to preve
Externí odkaz:
https://doaj.org/article/d8894b345c644576a38225157d9bfabc
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194482 (2018)
Understanding the regulation of insulin biosynthesis is important as it plays a central role in glucose metabolism. The mouse insulin gene2 (Ins2) has two splice variants; long (Ins2L) and short (Ins2S), that differ only in their 5'UTR sequence and I
Externí odkaz:
https://doaj.org/article/b5c7617d56834b1cbbbd651d8469bfd4
Autor:
Pabitra K. Sahoo, Prayag Murawala, Pravin T. Sawale, Manas R. Sahoo, Mukesh M. Tripathi, Swati R. Gaikwad, Vasudevan Seshadri, Jomon Joseph
Publikováno v:
Biology Open, Vol 1, Iss 2, Pp 109-119 (2012)
Summary Cells often respond to diverse environmental stresses by inducing stress granules (SGs) as an adaptive mechanism. SGs are generally assembled as a result of aggregation of mRNAs stalled in a translational pre-initiation complex, mediated by a
Externí odkaz:
https://doaj.org/article/d8f09c24894a424089847c8735275fb4
Autor:
Amaresh C Panda, Itishri Sahu, Shardul D Kulkarni, Jennifer L Martindale, Kotb Abdelmohsen, Arya Vindu, Jomon Joseph, Myriam Gorospe, Vasudevan Seshadri
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101084 (2014)
The 5' and the 3' untranslated regions (UTR) of the insulin genes are very well conserved across species. Although microRNAs (miRNAs) are known to regulate insulin secretion process, direct regulation of insulin biosynthesis by miRNA has not been rep
Externí odkaz:
https://doaj.org/article/5c7cfb7fbb754cd6a331bde6b05a6c6d
Autor:
Sakalya Chavan, Deepak Khuperkar, Akshay Lonare, Swagatika Panigrahi, Jayesh Bellare, Srikanth Rapole, Vasudevan Seshadri, Jomon Joseph
Publikováno v:
Cellular and Molecular Life Sciences. 79
Small extracellular vesicle (sEV)-mediated intercellular communication regulates multiple aspects of growth and development in multicellular organisms. However, the mechanism underlying cargo recruitment into sEVs is currently unclear. We show that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1893c6e13751ed3a26926c89fda80f
https://doi.org/10.1007/s00018-022-04422-y
https://doi.org/10.1007/s00018-022-04422-y
Publikováno v:
Biochemical Journal. 478:1117-1136
Asf1 is a highly conserved histone chaperone that regulates tightly coupled nucleosome assembly/disassembly process. We observed that Plasmodium falciparum Asf1 (PfAsf1) is ubiquitously expressed in different stages of the life cycle of the parasite.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051d29f72b6195eef0ee586bbfd2aad2
https://doi.org/10.1042/bcj20200891
https://doi.org/10.1042/bcj20200891
Autor:
Shehnaz Bano, Shyam More, Dattatray S. Mongad, Abdul Khalique, Dhiraj P. Dhotre, Manoj K. Bhat, Vasudevan Seshadri
Glucose homeostasis is maintained by insulin. It has been observed that hyperinsulinemia precedes insulin resistance and Type 2 diabetes. Insulin resistance is caused by multiple factors including genetic and diet. The molecular mechanism underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6960929018ac76518efe3f6f8803c96
https://doi.org/10.1101/2022.04.28.489884
https://doi.org/10.1101/2022.04.28.489884
Autor:
Vasudevan Seshadri, Rucha D. Sarwade, Shardul D. Kulkarni, Abdul Khalique, Naina Gaikwad, Poonam R. Pandey
Publikováno v:
Biochemical and Biophysical Research Communications. 526:618-625
Glucose mediated insulin biosynthesis is tightly regulated and shared between insulin granule proteins such as its processing enzymes, prohormone convertases, PC1/3 and PC2. However, the molecular players involved in the co-ordinated translation rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5d9ca9aea1b52aaa89c0687f60821c
https://doi.org/10.1016/j.bbrc.2020.03.106
https://doi.org/10.1016/j.bbrc.2020.03.106