Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Vasudeva, Ginjala"'
Autor:
Vasudeva Ginjala, Lizahira Rodriguez-Colon, Bratati Ganguly, Prawallika Gangidi, Paul Gallina, Husam Al-Hraishawi, Atul Kulkarni, Jeremy Tang, Jinesh Gheeya, Srilatha Simhadri, Ming Yao, Bing Xia, Shridar Ganesan
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Upon induction of DNA breaks, ATM activation leads to a cascade of local chromatin modifications that promote efficient recruitment of DNA repair proteins. Errors in this DNA repair pathway lead to genomic instability and cancer predispositi
Externí odkaz:
https://doaj.org/article/4981bcc1f4d943a6816b9de984a70298
Autor:
Ming Yao, Srilatha Simhadri, Atul Kulkarni, Paul Gallina, Vasudeva Ginjala, Lizahira Rodriguez-Colon, Bratati Ganguly, Prawallika Gangidi, Jeremy Tang, Husam Al-Hraishawi, Jinesh S. Gheeya, Shridar Ganesan, Bing Xia
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Upon induction of DNA breaks, ATM activation leads to a cascade of local chromatin modifications that promote efficient recruitment of DNA repair proteins. Errors in this DNA repair pathway lead to genomic instability and cancer predisposition. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b863170c4eedd9239721cd8bef438375
https://doi.org/10.1038/s41598-017-16480-5
https://doi.org/10.1038/s41598-017-16480-5
Publikováno v:
The Journal of biological chemistry. 292(2)
Induction of DNA damage induces a dynamic repair process involving DNA repair factors and epigenetic regulators. Chromatin alterations must occur for DNA repair factors to gain access to DNA lesions and restore original chromatin configuration to pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac66d46517e4d2cc45fc5f26f613c6e
https://pubmed.ncbi.nlm.nih.gov/27555324
https://pubmed.ncbi.nlm.nih.gov/27555324
Autor:
Jay Oza, Antoinette R. Tan, Honeah Sohail, Atul Kulkarni, Antonia Tomás-Loba, Zuzana Horejsi, Vasudeva Ginjala, Ming Yao, Simon J. Boulton, Shridar Ganesan
Publikováno v:
Journal of Biological Chemistry. 288:32357-32369
Activation of poly(ADP-ribose) polymerase (PARP) near sites of DNA breaks facilitates recruitment of DNA repair proteins and promotes chromatin relaxation in part through the action of chromatin-remodeling enzyme Amplified in Liver Cancer 1 (ALC1). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03967551865e2e6e4bb366ac28b0c9e4
https://doi.org/10.1074/jbc.m113.459164
https://doi.org/10.1074/jbc.m113.459164
Autor:
Dudley Chung, Zubaidah M. Ramdzan, Lam Leduy, Simran Kaur, Vasudeva Ginjala, Shridar Ganesan, Alain Nepveu, Caroline M. Donovan, Jordan Pinder, Graham Dellaire
Publikováno v:
Oncotarget
// Zubaidah M. Ramdzan 1 , Vasudeva Ginjala 3, * , Jordan B. Pinder 4, * , Dudley Chung 4, * , Caroline M. Donovan 1, 2, * , Simran Kaur 1, 2 , Lam Leduy 1 , Graham Dellaire 4 , Shridar Ganesan 3 , Alain Nepveu 1, 2, 3, 4 1 Goodman Cancer Research Ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c46ed560b2d0870ddd56f5b09245efb
https://pubmed.ncbi.nlm.nih.gov/28147323
https://pubmed.ncbi.nlm.nih.gov/28147323
Autor:
Atul Kulkarni, Jay Oza, Karim Nacerddine, Ming Yao, Maarten van Lohuizen, Sarah J. Hill, Elisabetta Citterio, Shridar Ganesan, Vasudeva Ginjala
Publikováno v:
Molecular and Cellular Biology. 31:1972-1982
DNA damage activates signaling pathways that lead to modification of local chromatin and recruitment of DNA repair proteins. Multiple DNA repair proteins having ubiquitin ligase activity are recruited to sites of DNA damage, where they ubiquitinate h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2b11d47ec64c9c7691b32a428f0129
https://doi.org/10.1128/mcb.00981-10
https://doi.org/10.1128/mcb.00981-10
Autor:
Wenqiang Yu, Vasudeva Ginjala, Vinod Pant, Igor Chernukhin, Joanne Whitehead, France Docquier, Dawn Farrar, Gholamreza Tavoosidana, Rituparna Mukhopadhyay, Chandrasekhar Kanduri, Mitsuo Oshimura, Andrew P Feinberg, Victor Lobanenkov, Elena Klenova, Rolf Ohlsson
Publikováno v:
Nature Genetics. 36:1105-1110
Chromatin insulators demarcate expression domains by blocking the cis effects of enhancers or silencers in a position-dependent manner. We show that the chromatin insulator protein CTCF carries a post-translational modification: poly(ADP-ribosyl)atio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372bbf997b6fdd5890e93f655e6872ba
https://doi.org/10.1038/ng1426
https://doi.org/10.1038/ng1426
Autor:
Erik Ullerås, Rolf Ohlsson, Chandrasekhar Kanduri, Claes Holmgren, Vinod Pant, Victor V. Lobanenkov, Gary C. Franklin, Vasudeva Ginjala
Publikováno v:
Journal of Biological Chemistry. 277:5707-5710
The 5′-flank of the H19 gene harbors a differentially methylated imprinting control region that represses the maternally derived Igf2 and paternally derivedH19 alleles. Here we show that the H19imprinting control region (ICR) is a potent silencer w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90fe975a6ef2cd42da32b59ab51b8488
https://doi.org/10.1074/jbc.c100552200
https://doi.org/10.1074/jbc.c100552200
Publikováno v:
Cancer Research. 77:1418-1418
Induction of DNA damage leads to a choreographed set of local chromatin changes that ensures an efficient recruitment of DNA repair factors. One principal regulator of the DNA Damage Response (DDR) signaling pathway is ATM kinase, which phosphorylate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::124fa95896909a8242cb8f386840e569
https://doi.org/10.1158/1538-7445.am2017-1418
https://doi.org/10.1158/1538-7445.am2017-1418
Autor:
Raimo Pakkanen, Vasudeva Ginjala
Publikováno v:
Journal of Immunoassay. 19:195-207
The major growth factors in bovine colostrum are transforming growth factor-beta s (TGF-beta 1 and TGF-beta 2) and insulin-like growth factors (IGF-1 and IGF-2). Recently, TGF-beta 2 content of bovine colostrum was measured using a TGF-beta 2 specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3620e2f5289a006d226e6349bb83fcc2
https://doi.org/10.1080/01971529808005480
https://doi.org/10.1080/01971529808005480