Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Vassilis I. Zannis"'
Autor:
Panagiotis Fotakis, Alexander Vezeridis, Ioannis Dafnis, Angeliki Chroni, Dimitris Kardassis, Vassilis I. Zannis
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 7, Pp 1310-1323 (2014)
The K146N/R147W substitutions in apoE3 were described in patients with a dominant form of type III hyperlipoproteinemia. The effects of these mutations on the in vivo functions of apoE were studied by adenovirus-mediated gene transfer in different mo
Externí odkaz:
https://doaj.org/article/f57e5e9dc9304df996cfb9ee31763f71
Autor:
Panagiotis Fotakis, Andreas K. Kateifides, Christina Gkolfinopoulou, Dimitra Georgiadou, Melissa Beck, Katharina Gründler, Angeliki Chroni, Efstratios Stratikos, Dimitris Kardassis, Vassilis I. Zannis
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 12, Pp 3281-3292 (2013)
We investigated the significance of hydrophobic and charged residues 218–226 on the structure and functions of apoA-I and their contribution to the biogenesis of HDL. Adenovirus-mediated gene transfer of apoA-I[L218A/L219A/V221A/L222A] in apoA-I−
Externí odkaz:
https://doaj.org/article/ec3f87325ac74e3eb340f2c0ed5c060d
Autor:
Panagiotis Fotakis, Ioanna Tiniakou, Andreas K. Kateifides, Christina Gkolfinopoulou, Angeliki Chroni, Efstratios Stratikos, Vassilis I. Zannis, Dimitris Kardassis
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 12, Pp 3293-3302 (2013)
We studied the significance of four hydrophobic residues within the 225–230 region of apoA-I on its structure and functions and their contribution to the biogenesis of HDL. Adenovirus-mediated gene transfer of an apoA-I[F225A/V227A/F229A/L230A] mut
Externí odkaz:
https://doaj.org/article/c0a5663a2e684e44867d80fe478d84b9
Autor:
Adelina Duka, Panagiotis Fotakis, Dimitra Georgiadou, Andreas Kateifides, Kalliopi Tzavlaki, Leonard von Eckardstein, Efstratios Stratikos, Dimitris Kardassis, Vassilis I. Zannis
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 1, Pp 107-115 (2013)
The objective of this study was to establish the role of apoA-IV, ABCA1, and LCAT in the biogenesis of apoA-IV-containing HDL (HDL-A-IV) using different mouse models. Adenovirus-mediated gene transfer of apoA-IV in apoA-I−/− mice did not change p
Externí odkaz:
https://doaj.org/article/10135362fd5d4dbdb4085ccc23cc9a45
Autor:
Andreas K. Kateifides, Irina N. Gorshkova, Adelina Duka, Angeliki Chroni, Dimitris Kardassis, Vassilis I. Zannis
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 7, Pp 1363-1372 (2011)
Abstract In this study, we investigated the role of positively and negatively charged amino acids within the 89-99 region of apolipoprotein A-I (apoA-I), which are highly conserved in mammals, on plasma lipid homeostasis and the biogenesis of HDL. We
Externí odkaz:
https://doaj.org/article/7ada80ffaa16446c960b9f97839a59e2
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 1, Pp 45-56 (2011)
We have used adenovirus-mediated gene transfer in apolipoprotein (apo)E−/− mice to elucidate the molecular etiology of a dominant form of type III hyperlipoproteinemia (HLP) caused by the R142C substitution in apoE4. It was found that low doses o
Externí odkaz:
https://doaj.org/article/9cdeb8397f19428b953e83c00b31f83f
Autor:
Dimitrios Iliopoulos, Konstantinos Drosatos, Yaeko Hiyama, Ira J. Goldberg, Vassilis I. Zannis
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 6, Pp 1513-1523 (2010)
We previously observed that treatment of mice with a dominant negative form of cJun (dn-cJun) increased the expression of genes involved in lipid metabolism and modulated the expression of nine microRNAs (miR). To investigate the potential effect of
Externí odkaz:
https://doaj.org/article/c0114b33d6814cf5b2feae01bde6fbec
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 3, Pp 521-529 (2006)
We have used adenovirus-mediated gene transfer and bolus injection of purified apolipoprotein E (apoE) in mice to determine the contribution of LDL receptor family members in the clearance of apoE-containing lipoproteins in vivo and the factors that
Externí odkaz:
https://doaj.org/article/98e616fa8b644dfbb4d19da8c177cc7b
Autor:
Gery Gerritsen, Patrick C.N. Rensen, Kyriakos E. Kypreos, Vassilis I. Zannis, Louis M. Havekes, Ko Willems van Dijk
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 7, Pp 1466-1473 (2005)
Adenovirus-mediated overexpression of human apolipoprotein E (apoE) induces hyperlipidemia by stimulating the VLDL-triglyceride (TG) production rate and inhibiting the LPL-mediated VLDL-TG hydrolysis rate. Because apoC-III is a strong inhibitor of TG
Externí odkaz:
https://doaj.org/article/976c513eb47643efaa19083ea29fdf91
Autor:
Thomas J.F. Nieland, Angeliki Chroni, Michael L. Fitzgerald, Zoltan Maliga, Vassilis I. Zannis, Tomas Kirchhausen, Monty Krieger
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 7, Pp 1256-1265 (2004)
Scavenger receptor class B type I (SR-BI) and ABCA1 are structurally dissimilar cell surface proteins that play key roles in HDL metabolism. SR-BI is a receptor that binds HDL with high affinity and mediates both the selective lipid uptake of cholest
Externí odkaz:
https://doaj.org/article/fc2eb6178bc1435f8108477e319ae8f1