Zobrazeno 1 - 10
of 447
pro vyhledávání: '"Vassilios Papadopoulos"'
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Background: The interstitial testicular Leydig cells are responsible for the production of testosterone, which functionally deteriorate with normal aging. Decreased expression of mitochondrial steroidogenic interactome proteins and diminished mitocho
Externí odkaz:
https://doaj.org/article/409c580d6a544c919e9fae47a2ae3e03
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Translocator protein (TSPO), a 18 kDa protein found in the outer mitochondrial membrane, has historically been associated with the transport of cholesterol in highly steroidogenic tissues though it is found in all cells throughout the mammalian body.
Externí odkaz:
https://doaj.org/article/1c389738868f4889b9279747ab5fcbfd
Publikováno v:
Human Genomics, Vol 16, Iss 1, Pp 1-21 (2022)
Abstract Background The detoxification of very long-chain and branched-chain fatty acids and the metabolism of cholesterol to form bile acids occur largely through a process called peroxisomal β-oxidation. Mutations in several peroxisomal proteins i
Externí odkaz:
https://doaj.org/article/cd909e05c38a45de80aaf3d8935c4cff
Autor:
Daniel B. Martinez–Arguelles, Jennifer W. Nedow, Hovhannes J. Gukasyan, Vassilios Papadopoulos
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
Cholesterol is the precursor of all steroid hormones, and the entry of cholesterol into the mitochondria is the rate-limiting step of steroidogenesis. Voltage-dependent anion channel (VDAC1) is an outer mitochondrial protein part of a multiprotein co
Externí odkaz:
https://doaj.org/article/c3ee8794f5c74d61b1aabddb90f426f9
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12511 (2023)
Mitochondrial membrane protein ATAD3A is a member of the AAA-domain-containing ATPases superfamily. It is important for the maintenance of mitochondrial DNA, structure, and function. In recent years, an increasing number of ATAD3A mutations have been
Externí odkaz:
https://doaj.org/article/c2f0a64a5b9246f8906b9501646d1c1d
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/18ebfd64053f4817a7a50a54c1b0ad5f
Autor:
Lu Li, Chantal M. Sottas, Hsu-Yu Chen, Yuchang Li, Haoyi Cui, Jason S. Villano, Joseph L. Mankowski, Paula M. Cannon, Vassilios Papadopoulos
Publikováno v:
Cells, Vol 12, Iss 8, p 1198 (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a SARS-like coronavirus, continues to produce mounting infections and fatalities all over the world. Recent data point to SARS-CoV-2 viral infections in the human testis. As low testostero
Externí odkaz:
https://doaj.org/article/3cf2e95788874e1daa615b9a382bf6ea
Autor:
Ioannis Papoulidis, Makarios Eleftheriades, Emmanouil Manolakos, Michael B. Petersen, Simoni Marina Liappi, Anastasia Konstantinidou, Maria Papamichail, Vassilios Papadopoulos, Antonios Garas, Sotirios Sotiriou, Ioannis Papastefanou, Georgios Daskalakis, Aleksandar Ristic
Publikováno v:
Children, Vol 9, Iss 12, p 1879 (2022)
Background: MCPH1 is known as the microcephalin gene (OMIM: *607117), of which the encoding protein is a basic regulator of chromosome condensation (BCRT-BRCA1 C-terminus). The microcephalin protein is made up of three BCRT domains and conserved tand
Externí odkaz:
https://doaj.org/article/dbbf4266c8834a15bb8a7887acc7e8ef
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12115 (2022)
Cholesterol is a lipid molecule essential for several key cellular processes including steroidogenesis. As such, the trafficking and distribution of cholesterol is tightly regulated by various pathways that include vesicular and non-vesicular mechani
Externí odkaz:
https://doaj.org/article/290eb266550845abaaab60cd629be0b2
Autor:
Aikaterini Kyriakou, Aikaterini Patsatsi, Vassilios Papadopoulos, Anna Kioumi, Ioannis Efstratiou, Elizabeth Lazaridou
Publikováno v:
Clinical Case Reports, Vol 7, Iss 4, Pp 695-698 (2019)
Key Clinical Message Palisaded neutrophilic granulomatous dermatitis is a cutaneous marker of a systemic disease. Clinicians’ goal should be directed toward determining an underlying condition. Even if the initial investigation is inconclusive, it
Externí odkaz:
https://doaj.org/article/1f8cc4e3f35e43cca7186b24817c8380