Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Vassilios Ladis"'
Publikováno v:
British Journal of Haematology. 151:504-508
Abnormal iron regulation in patients with thalassaemia intermedia may lead to iron overload even in the absence of transfusions. There are limited data on iron chelator use in patients with thalassaemia intermedia and no guidelines exist for the mana
Autor:
Evangelos Premetis, Vassilios Ladis, Ioannis Papassotiriou, Polyxeni Delaporta, Maria Papastamataki, Antonios Kattamis
Publikováno v:
Blood Cells, Molecules, and Diseases. 45:215-218
Patients with transfusion-dependent thalassemia major often develop liver fibrosis due to liver iron overload and/or hepatitis virus C (HCV) infection. Hyaluronic acid (HA) plays a prominent role in the pathogenesis of liver fibrosis and the elevatio
Autor:
Giorgos Chouliaras, Efstathios Gotsis, Vasilios Berdoukas, Antonis Kattamis, Vassilios Ladis, Sophie Mavrogeni
Publikováno v:
British Journal of Haematology. 151:397-401
Cardiac Magnetic Resonance (CMR) has replaced all other surrogate measurements in the determination of transfusional cardiac iron overload in patients with thalassaemia major. We aimed to determine the diagnostic value of CMR T2* with respect to card
Autor:
Panagiotis Moraitis, Christos Kattamis, Giorgos Chouliaras, Vassilios Ladis, Kirykos Zannikos, Vasilios Berdoukas, Eleni Berdoussi
Publikováno v:
European Journal of Haematology. 85:335-344
Objectives: Cardiac complications because of transfusional iron overload are the main cause of death in thalassaemia major. New chelators and iron monitoring methods such as cardiac magnetic resonance (CMR) became available after the year 2000. We ev
Autor:
Polyxeni Delaporta, Evgenios Goussetis, Ioannis Papassotiriou, Athanassia Sergounioti, Alexandra Margeli, Eugenia Hantzi, Vassilios Ladis, Antonis Kattamis
Publikováno v:
Blood Cells, Molecules, and Diseases. 44:152-155
Deferasirox (Exjade®) is a once-daily, oral iron chelator approved for the treatment of transfusional iron overload. This study was conducted to analyze changes in cystatin C concentration, an endogenous marker of glomerular filtration rate (GFR), i
Autor:
Genovefa Kolovou, Panagiotis Toulas, Sophie Mavrogeni, Efstathios Gotsis, Eleni Berdousis, Vassilios Ladis, Dimitrios Verganelakis, Athanasios Dritsas
Publikováno v:
The International Journal of Cardiovascular Imaging. 25:777-783
In b-thalassemia, myocardial iron overload contributes to heart failure, despite chelation treatment. We hypothesized that myocardial T2*, an index of iron overload, influences patients' physical activity. We assessed a thalassemic population by both
Publikováno v:
European Journal of Haematology. 82:381-387
Background: Cardiac complications are the leading cause of death in thalassaemic patients (TM) worldwide. Improved management protocols including new chelators and imaging have reduced cardiac-related deaths but also require more advanced analytical
Autor:
Efstathios Gotsis, Vassilios Ladis, Dimitrios Verganelakis, Panagiotis Toulas, Sophie Mavrogeni, Dennis V. Cokkinos, Eleni Berdousis
Publikováno v:
The International Journal of Cardiovascular Imaging. 24:849-854
Introduction b-Thalassemia major (TM) and thalassemia intermedia (TI) are forms of inherited hemoglobinopathies. Our aim was to evaluate a population of asymptomatic TM and TI patients using cardiovascular magnetic resonance (CMR). We hypothesized th
Publikováno v:
American Journal of Hematology. 68:221-224
We studied the changing pattern of the distribution of ferritin levels in 430 regularly-transfused patients with thalassemia in an attempt to evaluate compliance of chelation with deferoxamine. The study covered 15 years and was divided in three peri
Autor:
Vassilios, Ladis, Giorgos, Chouliaras, Vasilios, Berdoukas, Panagiotis, Moraitis, Kirykos, Zannikos, Eleni, Berdoussi, Christos, Kattamis
Publikováno v:
European Journal of Haematology
Objectives: Cardiac complications because of transfusional iron overload are the main cause of death in thalassaemia major. New chelators and iron monitoring methods such as cardiac magnetic resonance (CMR) became available after the year 2000. We ev