Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Vassil I. Ognyanov"'
Autor:
Vassil I. Ognyanov, M. A. Klitenick, J. Jia, D. Ashton, L. R. Kowalski, Stanley Charles Bell, M. De Vivo, C. Tsai, S. M. Lechner, B. N. Atkinson, C.-S. Tham
Publikováno v:
Molecular Pharmacology. 60:1414-1420
High-affinity glycine transport in neurons and glial cells is a primary means of inactivating synaptic glycine. We have synthesized a potent selective inhibitor of glycine transporter 1 (GlyT1), and characterized its activity using a quail fibroblast
Publikováno v:
Tetrahedron. 52:4363-4376
A base promoted ring expansion reaction of 2-oxocyclododecane-1-carbonitrile ( 6 ) with several diarylcarbodiimides gives 14-membered α-enaminolactams ( 12–17 ), whereas N -alkyl- N ′-aryl- and N , N ′-dialkylcarbodiimides do not react at all.
Publikováno v:
Journal of the American Chemical Society. 115:4429-4434
Syntheses of three optically pure, deoxygenated myo-inositol 1,4,5-trisphosphate analogues from quebrachitol are reported together with their binding affinities and 45 Ca 2+ release activity. The ligand-binding affinities of the analogues were determ
Publikováno v:
Tetrahedron Letters. 34:219-222
The synthesis of the (−)-sodium salt of the hexadeoxy-1, 4, 5-tris(methylenesulfonic acid) analogue of IP3 by use of an asymmetric Diels-Alder reaction is described together with the effects of this compound in binding to the IP3 receptor.
Publikováno v:
ChemInform. 22
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ChemInform. 23
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ChemInform. 25
Publikováno v:
ChemInform. 27
A base promoted ring expansion reaction of 2-oxocyclododecane-1-carbonitrile ( 6 ) with several diarylcarbodiimides gives 14-membered α-enaminolactams ( 12–17 ), whereas N -alkyl- N ′-aryl- and N , N ′-dialkylcarbodiimides do not react at all.
Publikováno v:
Helvetica Chimica Acta. 75:62-68
Synthesis of Macrocyles by Ring Enlargement of 14-Membered Cyclic Imides In the presence of a base, cyclododecanone derivative 2, activated in α-position by an allyloxycarbonyl group, underwent ring enlargement with isocyanates to give 14-membered i
Publikováno v:
Journal of the American Chemical Society. 113:6992-6996