IMRAS-A clinical trial of mosquito-bite immunization with live, radiation-attenuated P. falciparum sporozoites: Impact of immunization parameters on protective efficacy and generation of a repository of immunologic reagents.

Autor: Hickey B; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America., Teneza-Mora N; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America., Lumsden J; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Reyes S; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Sedegah M; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America., Garver L; Walter Reed Army Institute of Research, Silver Spring, MD, United States of America., Hollingdale MR; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Banania JG; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Ganeshan H; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Dowler M; Walter Reed Army Institute of Research, Silver Spring, MD, United States of America., Reyes A; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Tamminga C; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America., Singer A; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America., Simmons A; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Belmonte M; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Belmonte A; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Huang J; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Inoue S; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Velasco R; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Abot S; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Vasquez CS; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Guzman I; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Wong M; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Twomey P; Walter Reed Army Institute of Research, Silver Spring, MD, United States of America., Wojnarski M; Walter Reed Army Institute of Research, Silver Spring, MD, United States of America., Moon J; Walter Reed Army Institute of Research, Silver Spring, MD, United States of America., Alcorta Y; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Maiolatesi S; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Henry M. Jackson Foundation, Bethesda, MD, United States of America., Spring M; Henry M. Jackson Foundation, Bethesda, MD, United States of America.; Walter Reed Army Institute of Research, Silver Spring, MD, United States of America., Davidson S; Walter Reed Army Institute of Research, Silver Spring, MD, United States of America., Chaudhury S; Walter Reed Army Institute of Research, Silver Spring, MD, United States of America.; Biotechnology HPC Software Applications Institute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Development Command, Frederick, MD, United States of America., Villasante E; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America., Richie TL; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America., Epstein JE; Malaria Department, Naval Medical Research Center, Silver Spring, MD, United States of America.

Publikováno v: PloS one [PLoS One] 2020 Jun 17; Vol. 15 (6), pp. e0233840. Date of Electronic Publication: 2020 Jun 17 (Print Publication: 2020).