Výsledky vyhledávání - "Vasodilator Agents/pharmacology"

Autor: Henrik Steen Hansen, Udo Sechtem, Peter Ong, Eva Prescott, Ahmed Aziz

Publikováno v: Aziz, A, Hansen, H S, Sechtem, U, Prescott, E & Ong, P 2017, ' Sex-Related Differences in Vasomotor Function in Patients With Angina and Unobstructed Coronary Arteries ', Journal of the American College of Cardiology, vol. 70, no. 19, pp. 2349-2358 . https://doi.org/10.1016/j.jacc.2017.09.016

BACKGROUND: Coronary vasomotor dysfunction is an important mechanism for angina in patients with unobstructed coronary arteries.OBJECTIVES: The purpose of this study was to determine sex differences in the prevalence and clinical presentation of vaso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d0f0f3286f207f165ddb8816bfb135
https://doi.org/10.1016/j.jacc.2017.09.016

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Prevention of vascular dysfunction and arterial hypertension in mice generated by assisted reproductive technologies by addition of melatonin to culture media

Autor: Urs Scherrer, Pierre Dessen, Emrush Rexhaj, David Cerny, Stefano F. Rimoldi, Yves Allemann, Agim Pireva, Ariane Paoloni-Giacobino, Claudio Sartori

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology
American Journal of Physiology. Heart and Circulatory Physiology, Vol. 309, No 7 (2015) pp. H1151-H1156
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Assisted reproductive technologies (ART) induce vascular dysfunction in humans and mice. In mice, ART-induced vascular dysfunction is related to epigenetic alteration of the endothelial nitric oxide synthase (eNOS) gene, resulting in decreased vascul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13da4b294b26a37ea435a6982e6c7c9a

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Elastic behaviour of the carotid artery in intact spontaneously hypertensive rats

Autor: M. Niederberger, Bernard Waeber, Daniel Hayoz, B. Rutschmann, H. R. Brunner, C. Y. Genton

Publikováno v: European Heart Journal, vol. 14 Suppl C, pp. 10-3

Intact spontaneously hypertensive rats (SHR) were studied to assess the effect of prolonged antihypertensive treatment on the elastic behaviour of the external carotid artery. Thirty-week-old SHR received the ACE inhibitor captopril, the arteriolar d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3eca69e91c14a4e54579cf6e8d1c135
http://doc.rero.ch/record/297475/files/14-suppl_C-10.pdf

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Relaxing Responses to Hydrogen Peroxide and Nitric Oxide in Human Pericardial Resistance Arteries Stimulated with Endothelin-1

Autor: Maria Bloksgaard, Akhmadjon Irmukhamedov, Thomas Leurgans, Jo G. R. De Mey, Lars Riber

Publikováno v: Basic & Clinical Pharmacology & Toxicology, 122(1), 74-81. Wiley
Leurgans, T M, Bloksgaard, M, Irmukhamedov, A, Riber, L P & De Mey, J G R 2018, ' Relaxing Responses to Hydrogen Peroxide and Nitric Oxide in Human Pericardial Resistance Arteries Stimulated with Endothelin-1 ', Basic & Clinical Pharmacology & Toxicology, vol. 122, no. 1, pp. 74–81 . https://doi.org/10.1111/bcpt.12843

In human pericardial resistance arteries, effects of the endothelium-dependent vasodilator bradykinin are mediated by NO during contraction induced by K + or the TxA 2 analogue U46619 and by H 2O 2 during contraction by endothelin-1 (ET-1), respectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ba5906a985afe2601c210ea010bf8d
https://pubmed.ncbi.nlm.nih.gov/28686356

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Two-photon microscopy of vital murine elastic and muscular arteries. Combined structural and functional imaging with subcellular resolution

Publikováno v: Journal of vascular research. 44(2):87-98

Understanding vascular pathologies requires insight in the structure and function, and, hence, an imaging technique combining subcellular resolution, large penetration depth, and optical sectioning. We evaluated the applicability of two-photon laser-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::ddaceb233de5f8a26cbee71295b9f97f
https://doi.org/10.1159/000098259

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Soluble epoxide hydrolase inhibition improves coronary endothelial function and prevents the development of cardiac alterations in obese insulin-resistant mice

Autor: Dominique Guerrot, Isabelle Remy-Jouet, Antoine Ouvrard-Pascaud, Jeremy Bellien, Paul Mulder, Anne Marie Madec, Lionel Nicol, David Coquerel, Emmanuelle Loizon, Roméo Cassel, Najah Harouki, Vincent Richard, Christophe Morisseau, Clothilde Roche, Marie Besnier

Publikováno v: Am J Physiol Heart Circ Physiol
Am J Physiol Heart Circ Physiol, 2015, 308 (9), pp.1020-1029. ⟨10.1152/ajpheart.00465.2014⟩
AJP-Heart and Circulatory Physiology
AJP-Heart and Circulatory Physiology, American Physiological Society, 2015, 308 (9), pp.1020-1029. ⟨10.1152/ajpheart.00465.2014⟩
AJP-Heart and Circulatory Physiology, 2015, 308 (9), pp.1020-1029. ⟨10.1152/ajpheart.00465.2014⟩
AJP-Heart and Circulatory Physiology, American Physiological Society, 2015, 308 (9), pp.H1020-9. ⟨10.1152/ajpheart.00465.2014⟩

International audience; This study addressed the hypothesis that inhibiting the soluble epoxide hydrolase (sEH)-mediated degradation of epoxy-fatty acids, notably epoxyeicosatrienoic acids, has an additional impact against cardiovascular damage in in

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https://www.hal.inserm.fr/inserm-02296633

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SOMATOSENSORY EVOKED POTENTIAL AND HISTOPATHOLOGICAL INVESTIGATIONS IN ISCHAEMIA-INDUCED BRAIN DAMAGE: EFFECTS OF TRIMETAZIDINE IN RATS

Autor: Tülay Kurt, Atilla Oguzhanoglu, Ragip Ortaç, Bulent Turman

Publikováno v: International Journal of Neuroscience. 113:447-454

We studied the protective effects of trimetazidine (TMZ) on brain damage by means of somatosensory evoked potentials (SEP) in rats. The TMZ group did not show any statistically significant difference from the control group with respect to SEPs. Howev

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https://doi.org/10.1080/00207450390162209

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Recognition forces involved in mitochondrial binding to a low-affinity trimetazidine binding site related to anti-ischemic activity

Autor: Alain Le Ridant, Jean Paul Tillement, Georgette Plemper van Balen, Bernard Testa, Didier Morin, Pierre-Alain Carrupt

Publikováno v: Biochemical Pharmacology, Vol. 63, No 9 (2002) pp. 1691-1697

A number of heterogeneous drugs previously shown to bind to trimetazidine (TMZ) binding sites on mitochondria and to inhibit mitochondrial swelling (Morin et al., Br J Pharmacol 1998;123:1385-94) were investigated here for their physicochemical prope

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https://doi.org/10.1016/s0006-2952(02)00913-9

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Exercise training modulates functional sympatholysis and α-adrenergic vasoconstrictor responsiveness in hypertensive and normotensive individuals

Autor: Mortensen, Stefan, Nyberg, Michael, Gliemann, Lasse, Thaning, Pia, Saltin, Bengt, Hellsten, Ylva

Publikováno v: Mortensen, S, Nyberg, M, Gliemann, L, Thaning, P, Saltin, B & Hellsten, Y 2014, ' Exercise training modulates functional sympatholysis and α-adrenergic vasoconstrictor responsiveness in hypertensive and normotensive individuals ', Journal of Physiology, vol. 592, no. 14, pp. 3063-3073 . https://doi.org/10.1113/jphysiol.2014.273722

Key points: Essential hypertension is linked to an increased sympathetic vasoconstrictor activity and reduced tissue perfusion. Exercise training can improve the ability to override sympathetic vasoconstrictor activity. Here we show that 8 weeks of e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3062::999473496b0c269f30dfacc6aec23cf1
https://portal.findresearcher.sdu.dk/da/publications/0fb7f2d4-c3d4-49d7-8e7c-0cfd7cea3b6a

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Magnocellular neurons of the rat supraoptic nucleus are endowed with functional nicotinic acetylcholine receptors

Autor: Daniel Bertrand, Mario Raggenbass, Christophe Blanchet, Eliane Tribollet, M. Zaninetti

Publikováno v: Neuroscience, Vol. 95, No 2 (1999) pp. 319-323

Acetylcholine can stimulate the release of vasopressin. In organ-cultured hypothalamo-neurohypophyseal systems, acetylcholine enhanced vasopressin release by acting in or near the supraoptic nucleus Extracellular recordings suggested that acetylcholi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cef4af8d7a8882915012fdba29bdd7
https://doi.org/10.1016/s0306-4522(99)00477-7

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