Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Vasisht Tadigotla"'
Autor:
Sudipto K. Chakrabortty, Yevgenia L. Khodor, Robert R. Kitchen, Dulaney L. Miller, Kailey M. Babcock, Kyle S. Manning, Steven P. Lang, Vasisht Tadigotla, Wei Yu, Eric Bershad, Johan Skog, Susana Zanello
Publikováno v:
npj Microgravity, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract Molecular profiling to characterize the effects of environmental exposures is important from the human health and performance as well as the occupational medicine perspective in space exploration. We have developed a novel exosome-based plat
Externí odkaz:
https://doaj.org/article/7713ca03e5524ed589651bd4b3983ad3
Autor:
James McKiernan, Mikkel Noerholm, Vasisht Tadigotla, Sonia Kumar, Phillipp Torkler, Grannum Sant, Jason Alter, Michael J. Donovan, Johan Skog
Publikováno v:
BMC Urology, Vol 20, Iss 1, Pp 1-6 (2020)
Abstract Background Initial prostate biopsy often fails to identify prostate cancer resulting in patient anxiety, especially when clinical features such as prostate specific antigen (PSA) remain elevated, leading to the need for repeat biopsies. Pros
Externí odkaz:
https://doaj.org/article/a6a722e19e074d229423f0a27222ffe3
Autor:
Kevin McKernan, Jessica Spangler, Lei Zhang, Vasisht Tadigotla, Yvonne Helbert, Theodore Foss, Douglas Smith
Publikováno v:
F1000Research, Vol 4 (2016)
The Center for Disease Control estimates 128,000 people in the U.S. are hospitalized annually due to food borne illnesses. This has created a demand for food safety testing targeting the detection of pathogenic mold and bacteria on agricultural produ
Externí odkaz:
https://doaj.org/article/177ac55dca2f42608a478aaef6e759f6
Autor:
Adam H Freedman, Rena M Schweizer, Diego Ortega-Del Vecchyo, Eunjung Han, Brian W Davis, Ilan Gronau, Pedro M Silva, Marco Galaverni, Zhenxin Fan, Peter Marx, Belen Lorente-Galdos, Oscar Ramirez, Farhad Hormozdiari, Can Alkan, Carles Vilà, Kevin Squire, Eli Geffen, Josip Kusak, Adam R Boyko, Heidi G Parker, Clarence Lee, Vasisht Tadigotla, Adam Siepel, Carlos D Bustamante, Timothy T Harkins, Stanley F Nelson, Tomas Marques-Bonet, Elaine A Ostrander, Robert K Wayne, John Novembre
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005851 (2016)
Controlling for background demographic effects is important for accurately identifying loci that have recently undergone positive selection. To date, the effects of demography have not yet been explicitly considered when identifying loci under select
Externí odkaz:
https://doaj.org/article/73f7b6a47b734c7b8753485838c3cece
Autor:
Adam H Freedman, Ilan Gronau, Rena M Schweizer, Diego Ortega-Del Vecchyo, Eunjung Han, Pedro M Silva, Marco Galaverni, Zhenxin Fan, Peter Marx, Belen Lorente-Galdos, Holly Beale, Oscar Ramirez, Farhad Hormozdiari, Can Alkan, Carles Vilà, Kevin Squire, Eli Geffen, Josip Kusak, Adam R Boyko, Heidi G Parker, Clarence Lee, Vasisht Tadigotla, Alan Wilton, Adam Siepel, Carlos D Bustamante, Timothy T Harkins, Stanley F Nelson, Elaine A Ostrander, Tomas Marques-Bonet, Robert K Wayne, John Novembre
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004016 (2014)
To identify genetic changes underlying dog domestication and reconstruct their early evolutionary history, we generated high-quality genome sequences from three gray wolves, one from each of the three putative centers of dog domestication, two basal
Externí odkaz:
https://doaj.org/article/0cbadcf2015f4817b3d095bbff43abc3
Autor:
Kevin J McKernan, Jessica Spangler, Lei Zhang, Vasisht Tadigotla, Stephen McLaughlin, Jason Warner, Amir Zare, Richard G Boles
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96492 (2014)
We have developed a PCR method, coined Déjà vu PCR, that utilizes six nucleotides in PCR with two methyl specific restriction enzymes that respectively digest these additional nucleotides. Use of this enzyme-and-nucleotide combination enables what
Externí odkaz:
https://doaj.org/article/8f03bc36dff14e60b4fbb2011b8f378d
Autor:
Johan K. Skog, Luis E. Raez, Bakhos A. Tannous, Jihane Tannous, Mikkel Noerholm, Anne Krug, Mitch Raponi, Chris Karlovich, Raajdeep Venkatesan, Mia Sher, Patricia L. Neal, John Healy, James Hurley, Vasisht Tadigotla, Dominik G. Grimm, Elena Castellanos-Rizaldos
Supplementary Table 1. Clinical characteristics of patients included in the study (T790M positive/negative and the different pools of plasma from healthy donors); Supplementary Table 2. Mutant admixtures used as part of the analytical validation. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d1407b8d77a4c25a925242e7b889a1
https://doi.org/10.1158/1078-0432.22469558.v1
https://doi.org/10.1158/1078-0432.22469558.v1
Autor:
Johan K. Skog, Luis E. Raez, Bakhos A. Tannous, Jihane Tannous, Mikkel Noerholm, Anne Krug, Mitch Raponi, Chris Karlovich, Raajdeep Venkatesan, Mia Sher, Patricia L. Neal, John Healy, James Hurley, Vasisht Tadigotla, Dominik G. Grimm, Elena Castellanos-Rizaldos
Purpose: About 60% of non–small cell lung cancer (NSCLC) patients develop resistance to targeted epidermal growth factor receptor (EGFR) inhibitor therapy through the EGFR T790M mutation. Patients with this mutation respond well to third-generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd7c2b5696d5c2befad5d9c0e112d25
https://doi.org/10.1158/1078-0432.c.6527291.v1
https://doi.org/10.1158/1078-0432.c.6527291.v1
Autor:
Alexander Kretschmer, Ronald Tutrone, Jason Alter, Elena Berg, Christian Fischer, Sonia Kumar, Phillipp Torkler, Vasisht Tadigotla, Michael Donovan, Grannum Sant, Johan Skog, Mikkel Noerholm
Publikováno v:
World Journal of Urology. 40:983-989
Purpose ExoDx Prostate IntelliScore (EPI) is a non-invasive urine exosome RNA-based test for risk assessment of high-grade prostate cancer. We evaluated the association of pre-biopsy test results with post-radical prostatectomy (RP) outcomes to under
Autor:
Michael J. Donovan, Ronald F. Tutrone, Johan Skog, Christian Fischer, James M. McKiernan, Vasisht Tadigotla, Mikkel Noerholm, Gordon D. Brown, Erik Margolis, Alan W. Partin, Ballentine Carter, Phillipp Torkler
Publikováno v:
Prostate Cancer and Prostatic Diseases. 25:296-301
Background The ability to discriminate indolent from clinically significant prostate cancer (PC) at the initial biopsy remains a challenge. The ExoDx Prostate (IntelliScore) (EPI) test is a noninvasive liquid biopsy that quantifies three RNA targets