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Publikováno v:
Acta Pharmaceutica. 60
Metoprolol, 1-isopropylamino-3-[4-(2-methoxy-ethyl)-phenoxy]-2-propanol, is a b1-selective aryloxy propanolamine used in the treatment of cardiovascular disorders such as hypertension, arrhythmia and heart failure (1). The drug is a lipophilic adreno
Publikováno v:
Acta Pharmaceutica
Volume 60
Issue 2
Volume 60
Issue 2
A high-performance liquid chromatography-tandem mass spectrometric method was developed and validated for the determination of metoprolol in human plasma. The analyte and internal standard, nevirapine,were extracted from plasma matrix by liquid–liq