Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Vasily V. Stavchansky"'
Autor:
Vasily V. Stavchansky, Vadim V. Yuzhakov, Larisa E. Sevan’kaeva, Natalia K. Fomina, Anastasia E. Koretskaya, Alina E. Denisova, Ivan V. Mozgovoy, Leonid V. Gubsky, Ivan B. Filippenkov, Nikolay F. Myasoedov, Svetlana A. Limborska, Lyudmila V. Dergunova
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 2071-2092 (2024)
Stroke remains the second leading cause of death worldwide. The development of new therapeutic agents focused on restoring vascular function and neuroprotection of viable tissues is required. In this study the neuroprotective activity of melanocortin
Externí odkaz:
https://doaj.org/article/b17876218b024ea19d3d862f353204fd
Autor:
Ivan B. Filippenkov, Julia A. Remizova, Alina E. Denisova, Vasily V. Stavchansky, Ksenia D. Golovina, Leonid V. Gubsky, Svetlana A. Limborska, Lyudmila V. Dergunova
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Ischemic stroke is one of the most severe polygenic brain diseases. Here, we performed further functional genetic analysis of the processes occurring in the contralateral hemisphere (CH) after ischemia–reperfusion injury in rat brain. Comp
Externí odkaz:
https://doaj.org/article/97ff7a1652614317b2bd0032f0d1a6ec
Autor:
Ivan B. Filippenkov, Julia A. Remizova, Alina E. Denisova, Vasily V. Stavchansky, Ksenia D. Golovina, Leonid V. Gubsky, Svetlana A. Limborska, Lyudmila V. Dergunova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7308 (2022)
Ischemic stroke is a multifactorial disease with a complex etiology and global consequences. Model animals are widely used in stroke studies. Various controls, either brain samples from sham-operated (SO) animals or symmetrically located brain sample
Externí odkaz:
https://doaj.org/article/7991aceea65345c2a05590c21273e888
Autor:
Lyudmila V. Dergunova, Ivan B. Filippenkov, Vasily V. Stavchansky, Alina E. Denisova, Vadim V. Yuzhakov, Sergey A. Mozerov, Leonid V. Gubsky, Svetlana A. Limborska
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-16 (2018)
Abstract Background The transient middle cerebral artery occlusion (tMCAO) model is used for studying the molecular mechanisms of ischemic damage and neuroprotection. Numerous studies have demonstrated the role of individual genes and associated sign
Externí odkaz:
https://doaj.org/article/ed65ea9533e34a2ba343405e1cab6b78
Autor:
Ivan B. Filippenkov, Vasily V. Stavchansky, Natalya Yu. Glazova, Elena A. Sebentsova, Julia A. Remizova, Liya V. Valieva, Natalia G. Levitskaya, Nikolai F. Myasoedov, Svetlana A. Limborska, Lyudmila V. Dergunova
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 10054 (2021)
Natural melanocortins (MCs) have been used in the successful development of drugs with neuroprotective properties. Here, we studied the behavioral effects and molecular genetic mechanisms of two synthetic MC derivatives-ACTH(4–7)PGP (Semax) and ACT
Externí odkaz:
https://doaj.org/article/c562a17b19f14caaabaa6d7f4ce8cb8c
Autor:
Olga Yu. Sudarkina, Ivan B. Filippenkov, Vasily V. Stavchansky, Alina E. Denisova, Vadim V. Yuzhakov, Larisa E. Sevan’kaeva, Liya V. Valieva, Julia A. Remizova, Veronika G. Dmitrieva, Leonid V. Gubsky, Nikolai F. Myasoedov, Svetlana A. Limborska, Lyudmila V. Dergunova
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6179 (2021)
The Semax (Met-Glu-His-Phe-Pro-Gly-Pro) peptide is a synthetic melanocortin derivative that is used in the treatment of ischemic stroke. Previously, studies of the molecular mechanisms underlying the actions of Semax using models of cerebral ischemia
Externí odkaz:
https://doaj.org/article/aee42ef1bfe8425083ea7666d0c68a61
Autor:
Dergunova, Ivan B. Filippenkov, Julia A. Remizova, Vasily V. Stavchansky, Alina E. Denisova, Leonid V. Gubsky, Nikolay F. Myasoedov, Svetlana A. Limborska, Lyudmila V.
Publikováno v:
Genes; Volume 14; Issue 7; Pages: 1382
Ischemic stroke is an acute local decrease in cerebral blood flow due to a thrombus or embolus. Of particular importance is the study of the genetic systems that determine the mechanisms underlying the formation and maintenance of a therapeutic windo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::66ab6e503fbd1e88dbc532f8da2f4a95
Autor:
Vasily V. Stavchansky, Ivan B. Filippenkov, Julia A. Remizova, Alina E. Denisova, Ivan V. Mozgovoy, Leonid V. Gubsky, Nikolay F. Myasoedov, Lyudmila A. Andreeva, Svetlana A. Limborska, Lyudmila V. Dergunova
Publikováno v:
Genes; Volume 13; Issue 12; Pages: 2380
Glyprolines are Gly-Pro (GP)- or Pro-Gly (PG)-containing biogenic peptides. These peptides can act as neutrophil chemoattractants, or atheroprotective, anticoagulant, and neuroprotective agents. The Pro-Gly-Pro (PGP) tripeptide is an active factor of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ad84bee244cb352e27665d705e279e
Autor:
Alina E. Denisova, L E Sevan'kaeva, V V Yuzhakov, O.Y. Sudarkina, N.F. Myasoedov, L.V. Dergunova, Ivan B. Filippenkov, Svetlana A. Limborska, V G Dmitrieva, Liya V Valieva, Leonid V. Gubsky, Vasily V Stavchansky
Publikováno v:
Молекулярная биология. 55:402-411
Due to its nootropic, neuroprotective, and immunomodulatory effects, the peptide Semax is utilized in the treatment of ischemic stroke. Our earlier RNA-Seq analysis of the transcriptome in an ischemic model of transient occlusion of the middle cerebr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6afd246b6537292ae4ceef7569fd3e24
https://doi.org/10.31857/s0026898421010043
https://doi.org/10.31857/s0026898421010043
Autor:
Ivan B. Filippenkov, Leonid V. Gubsky, Svetlana A. Limborska, Julia A Remizova, Vasily V. Stavchansky, Elizaveta I. Zaytceva, Liya V Valieva, Lyudmila V. Dergunova, Ivan V. Mozgovoy, Alina E. Denisova
Publikováno v:
Genes; Volume 12; Issue 12; Pages: 1870
Genes
Genes, Vol 12, Iss 1870, p 1870 (2021)
Genes
Genes, Vol 12, Iss 1870, p 1870 (2021)
Ischemic brain stroke is one of the most serious and socially significant diseases. In addition to messenger RNAs (mRNAs), encoding protein, the study of regulatory RNAs in ischemic has exceptional importance for the development of new strategies for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e17d100c5a7c0e827f1dbd6d4c7c01