Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vasily V. Ivanenkov"'
Publikováno v:
Protein Engineering Design and Selection. 23:579-588
We adapted the method of epitope mapping by site-directed masking, which was described for purified soluble antigens [Paus,D. and Winter,G. (2006) Proc. Natl Acad. Sci. USA, 103, 9172–9177.], to map the binding site of an inhibitory monoclonal anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75c94ceb48e1513841417628a0636b0
https://doi.org/10.1093/protein/gzq027
https://doi.org/10.1093/protein/gzq027
Autor:
Mercedes N. Munkonda, Alain Tremblay, Jean Sévigny, Terence L. Kirley, Julie Pelletier, Beat M. Künzli, Vasily V. Ivanenkov, Michel Fausther
Publikováno v:
FEBS Journal. 276:479-496
The study and therapeutic modulation of purinergic signaling is hindered by a lack of specific inhibitors for NTP diphosphohydrolases (NTPDases), which are the terminating enzymes for these processes. In addition, little is known of the NTPDase prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235f3d5f88fbedbe83551b71fe2c51c1
https://doi.org/10.1111/j.1742-4658.2008.06797.x
https://doi.org/10.1111/j.1742-4658.2008.06797.x
Publikováno v:
Biochemistry. 42:2412-2421
A newly discovered human analogue of a bed bug apyrase, which we named hSCAN-1 for human soluble calcium-activated nucleotidase-1, was expressed in bacteria, refolded from inclusion bodies, purified, and characterized. This apyrase, which is distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95fe986f0e08f007c772f0ff46a6ade
https://doi.org/10.1021/bi026763b
https://doi.org/10.1021/bi026763b
Publikováno v:
Journal of Biological Chemistry. 277:6162-6169
Cysteine-to-serine mutations were constructed to test the functional and structural significance of the three non-extracellular cysteine residues in ecto-nucleoside-triphosphate diphosphohydrolase 3 (eNTPDase3). None of these cysteines were found to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc175aaee1ee836a554cb917e605caca
https://doi.org/10.1074/jbc.m110105200
https://doi.org/10.1074/jbc.m110105200
Publikováno v:
Vasily Ivanenkov
Novel peptide motives targeting endocytosing receptors were isolated from phage display libraries of random peptides by recovering internalized phage from mammalian cells. The peptide-presenting phage selected by internalization in HEp-2 and ECV304 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba87a5bd84ed15a0885e3696f8578aeb
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Impairment of ribosome biogenesis leads to p53 induction and cell cycle arrest, a checkpoint involved in human disease. Induction of p53 is attributed to the binding and inhibition of human double minute 2 (Hdm2) by a subset of ribosomal proteins (RP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc6c4c777753c41b3fc224b61123bc2
https://pubmed.ncbi.nlm.nih.gov/22588717
https://pubmed.ncbi.nlm.nih.gov/22588717
Publikováno v:
Vasily Ivanenkov
The expression of annexins, a family of Ca2+/phospholipid-binding proteins, was analyzed by biochemical and immunological criteria in the fish Misgurnus fossilis (loach), which is a good model system to study embryonic events. Five different annexins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab1aac8dd4d5890bd093a86487a25af
https://doi.org/10.1016/0014-5793(94)00956-2
https://doi.org/10.1016/0014-5793(94)00956-2
Ecto-nucleoside triphosphate diphosphohydrolases, NTPDase1 (CD39) and NTPDase3, are integral plasma membrane proteins that hydrolyze extracellular nucleotides, thereby modulating the function of purinergic receptors. During processing in the secretor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085ceb1b4b4ec7acfb2c86a02a45d21e
https://europepmc.org/articles/PMC2562647/
https://europepmc.org/articles/PMC2562647/
Publikováno v:
Biochemistry. 44(25)
Cell-surface nucleotidases (NTPDases) contain 10 invariant cysteine residues in their extracellular regions. To investigate disulfide structure in human NTPDase3, we made single and double mutants of these 10 cysteines, and analyzed their enzymatic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68fe0560e6461ec91bf39c2d0a3619f
https://pubmed.ncbi.nlm.nih.gov/15966724
https://pubmed.ncbi.nlm.nih.gov/15966724
Publikováno v:
Archives of biochemistry and biophysics. 395(1)
Glycine residues are recognized as important structural determinants in nucleotide-binding domains of many enzymes. The functional significance of seven glycine residues invariant in all 22 eNTPDase sequences was therefore examined. Glycine-to-alanin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8dcfdf287308b9f44842d068a0bb576
https://pubmed.ncbi.nlm.nih.gov/11673870
https://pubmed.ncbi.nlm.nih.gov/11673870