Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Vasily V Sinyov"'
Autor:
Margarita A Sazonova, Andrey V Zhelankin, Valeria A Barinova, Vasily V Sinyov, Zukhra B Khasanova, Yuri V Bobryshev, Anton Y Postnov, Igor A Sobenin, Alexander N Orekhov
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
With aim of detection the spectrum of mitochondrial DNA mutations in patients with carotid atherosclerosis from Moscow Region, we used a Roche 454 high-throughput sequencing of the whole mitochondrial genome. We have found that the presence of a numb
Externí odkaz:
https://doaj.org/article/641cd436abe84094a5d1286d591ea503
Autor:
Natalya A. Doroschuk, Anton Yu Postnov, Alexander D. Doroschuk, Anastasia I. Ryzhkova, Vasily V. Sinyov, Marina D. Sazonova, Victoria A. Khotina, Alexander N. Orekhov, Igor A. Sobenin, Margarita A. Sazonova
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 499-504 (2021)
Aim: The aim of this work was to study the effect of telomere length in the chromosomes of nuclear blood cells in individuals with coronary heart disease (CHD) on the development of cardiovascular complications (CVC). Materials and methods: DNA was i
Externí odkaz:
https://doaj.org/article/5d2c036f6ab54bb9a62f494a97d364f7
Autor:
Alexander N. Orekhov, Nikita G. Nikiforov, Andrey V. Omelchenko, Vasily V. Sinyov, Igor A. Sobenin, Andrey Y. Vinokurov, Varvara A. Orekhova
Publikováno v:
Life, Vol 12, Iss 8, p 1153 (2022)
Chronic human diseases, especially age-related disorders, are often associated with chronic inflammation. It is currently not entirely clear what factors are responsible for the sterile inflammatory process becoming chronic in affected tissues. This
Externí odkaz:
https://doaj.org/article/7dbc9b92126945cc9d301b9541902d43
Autor:
Victoria A. Khotina, Vladislav A. Kalmykov, Alexander D. Zhuravlev, Vasily V. Sinyov, Igor A. Sobenin, Alexander N. Orekhov, Vasily N. Sukhorukov
BackgroundIt was assumed that the cause of chronic inflammation in atherosclerosis is a disturbance of the innate immunity response, caused, among other factors, by mitochondrial dysfunctions. It was also suggested that mitochondrial dysfunction may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::035037cf670c5f01d799268944e408b6
https://doi.org/10.1101/2023.04.21.537899
https://doi.org/10.1101/2023.04.21.537899
Autor:
Tatiana V. Kirichenko, Anastasia I. Ryzhkova, Vasily V. Sinyov, Marina D. Sazonova, Varvara A. Orekhova, Vasily P. Karagodin, Elena V. Gerasimova, Mikhail I. Voevoda, Alexander N. Orekhov, Yulia I. Ragino, Igor A. Sobenin, Margarita A. Sazonova
Publikováno v:
Life, Vol 10, Iss 9, p 160 (2020)
The search for markers of predisposition to atherosclerosis development is very important for early identification of individuals with a high risk of cardiovascular disease. The aim of the present study was to investigate the association of mitochond
Externí odkaz:
https://doaj.org/article/2d21e94309b04befba9ab749671063e9
Autor:
A.I. Ryzhkova, Alexander N. Orekhov, Margarita A. Sazonova, N.A. Doroschuk, Alexander D. Doroschuk, M.D. Sazonova, Anton Y. Postnov, Igor A. Sobenin, Victoria A. Khotina, Vasily V. Sinyov
Publikováno v:
Toxicology Reports, Vol 8, Iss, Pp 499-504 (2021)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • We studied a sample of patients with coronary heart disease. • We analyzed the telomere length in this sample. • We compared telomere length in patients and conventionally healthy study participants. • Pat
Highlights • We studied a sample of patients with coronary heart disease. • We analyzed the telomere length in this sample. • We compared telomere length in patients and conventionally healthy study participants. • Pat
Autor:
Tatiana V. Kirichenko, Margarita A. Sazonova, Alexander N. Orekhov, Igor A. Sobenin, Vasily V. Sinyov, V P Karagodin, N.A. Doroschuk, M.D. Sazonova, A.I. Ryzhkova
Publikováno v:
Current Pharmaceutical Design. 27:177-184
Background: The present review article considers some chronic diseases of vascular and metabolic genesis, the causes of which may be mitochondrial dysfunction. Very often, in the long course of the disease, complications may occur, leading to myocard
Autor:
Alexander N. Orekhov, Z.B. Khasanova, M.D. Sazonova, A.I. Ryzhkova, V P Karagodin, Margarita A. Sazonova, Nadezhda A. Nikitina, Igor A. Sobenin, Vasily V. Sinyov
Publikováno v:
Current Pharmaceutical Design. 25:693-699
Objective: In this review article, we analyzed the literature on the creation of cultures containing mutations associated with cardiovascular diseases (CVD) using transfection, transduction and editing of the human genome. Methods: We described diffe
Publikováno v:
Atherosclerosis. 331:e89-e90
Autor:
Z.B. Khasanova, Vasily V. Sinyov, V.A. Kalmykov, Victoria A. Khotina, Vasily N. Sukhorukov, Igor A. Sobenin
Publikováno v:
Atherosclerosis. 331:e70-e71