Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Vasilios A. Morikis"'
Autor:
Paula M. Godoy, Abimbola Oyedeji, Jacqueline L. Mudd, Vasilios A. Morikis, Anna P. Zarov, Gregory D. Longmore, Ryan C. Fields, Charles K. Kaufman
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Small nucleotide variants in non-coding regions of the genome can alter transcriptional regulation, leading to changes in gene expression which can activate oncogenic gene regulatory networks. Melanoma is heavily burdened by non-coding varia
Externí odkaz:
https://doaj.org/article/74b900f059654a8b8f4f21f8c7bb487d
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils are essential to protect the host against invading pathogens but can promote disease progression in sickle cell disease (SCD) by becoming adherent to inflamed microvascular networks in peripheral tissue throughout the body. During the inf
Externí odkaz:
https://doaj.org/article/da729016f4884c87b849c6f33ad0f150
Autor:
Rohith R. Mohan, Mark Wilson, Ronald D. Gorham, Reed E. S. Harrison, Vasilios A. Morikis, Chris A. Kieslich, Asuka A. Orr, Alexis V. Coley, Phanourios Tamamis, Dimitrios Morikis
Publikováno v:
ACS Omega, Vol 3, Iss 6, Pp 6427-6438 (2018)
Externí odkaz:
https://doaj.org/article/275d093bb4fb465ab24b9e2d7c7c11b9
Autor:
Vasilios A. Morikis, Scott I. Simon
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Neutrophils are the most motile of mammalian cells, a feature that enables them to protect the host against the rapid spread of pathogens from tissue into the circulatory system. A critical process is the recruitment of neutrophils to inflamed endoth
Externí odkaz:
https://doaj.org/article/07ee83fb867b401fb08335540dcbb43a
Autor:
Emma C. Skoog, Vasilios A. Morikis, Miriam E. Martin, Greg A. Foster, Lucy P. Cai, Lori M. Hansen, Beibei Li, Jennifer A. Gaddy, Scott I. Simon, Jay V. Solnick
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Strains of Helicobacter pylori that cause ulcer or gastric cancer typically express a type IV secretion system (T4SS) encoded by the cag pathogenicity island (cagPAI). CagY is an ortholog of VirB10 that, unlike other VirB10 orthologs, has a
Externí odkaz:
https://doaj.org/article/d5a1ea5e1a5f4d1786af03886b030a49
Autor:
Vasilios Aris Morikis, Szu Jung Chen, Julianna Madigan, Myung Hyun Jo, Lisette Caroline Werba, Taekjip Ha, Scott Irwin Simon
Publikováno v:
Cells; Volume 11; Issue 18; Pages: 2822
Cells, vol 11, iss 18
Cells, vol 11, iss 18
On arrested neutrophils a focal adhesive cluster of ~200 high affinity (HA) β2-integrin bonds under tension is sufficient to trigger Ca2+ flux that signals an increase in activation in direct proportion to increments in shear stress. We reasoned tha
Autor:
Vasilios Aris, Morikis, Szu Jung, Chen, Julianna, Madigan, Myung Hyun, Jo, Lisette Caroline, Werba, Taekjip, Ha, Scott Irwin, Simon
Publikováno v:
Cells. 11(18)
On arrested neutrophils a focal adhesive cluster of ~200 high affinity (HA) β
Autor:
Eytan R Barnea, Ina Rohwedder, Thomas Gudermann, Sergi Masgrau-Alsina, Susanna Zierler, Scott I. Simon, Anna Yevtushenko, Markus Sperandio, Oliver Soehnlein, Annika Bertsch, Roland Immler, Markus Moser, Wiebke Nadolni, Markus Rehberg, Monika Pruenster, Tobias Schroll, Vasilios A. Morikis
Publikováno v:
Cardiovasc. Res. 118, 1289–1302 (2022)
Aims Neutrophil trafficking within the vasculature strongly relies on intracellular calcium signaling. Sustained Ca2+ influx into the cell requires a compensatory efflux of potassium to maintain membrane potential. Here, we aimed to investigate wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3086c045419381c6b4e58c771708946a
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61889
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61889
Publikováno v:
Journal of Leukocyte Biology. 107:167-169
Discussion on the flexible kink produced in the β2-integrin transmembrane domain blocking mechanotransduction of signals necessary for neutrophil arrest and spreading.
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Neutrophils are essential to protect the host against invading pathogens but can promote disease progression in sickle cell disease (SCD) by becoming adherent to inflamed microvascular networks in peripheral tissue throughout the body. During the inf