Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vasiliki Michaki"'
Autor:
Loukia Parisiadou, Ioanna Bethani, Vasiliki Michaki, Kaliopi Krousti, Georgia Rapti, Spiros Efthimiopoulos
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 3, Pp 353-364 (2008)
The study of Amyloid Precursor Protein (APP) processing has been the focus of considerable interest, since it leads to Aβ peptide generation, the main constituent of neuritic plaques found in brains of Alzheimer's disease patients. Therefore, the id
Externí odkaz:
https://doaj.org/article/8fcbdae31aaa47c68e3b2b283413b506
Autor:
Ioanna Bethani, Loukia Parisiadou, Georgia Rapti, Vasiliki Michaki, Kaliopi Krousti, Spiros Efthimiopoulos
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 3, Pp 353-364 (2008)
The study of Amyloid Precursor Protein (APP) processing has been the focus of considerable interest, since it leads to Abeta peptide generation, the main constituent of neuritic plaques found in brains of Alzheimer's disease patients. Therefore, the
Autor:
Francesc X. Guix, Danyelle M. Townsend, Sebastian Munck, Colin Dingwall, Bart De Strooper, Krist'l Vennekens, Kenneth D. Tew, John B. Davis, Tina Wahle, Fabian Feiguin, Vasiliki Michaki, Carlos G. Dotti
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Clinical, pharmacological, biochemical, and genetic evidence support the notion that alteration of cholesterol homeostasis strongly predisposes to Alzheimer disease (AD). The ATP-binding cassette transporter-2 (Abca2), which plays a role in intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680cca549dd90002a69190a742d21aa9
http://hdl.handle.net/10261/112323
http://hdl.handle.net/10261/112323
Autor:
Iva, Nesic, Francesc X, Guix, Krist'l, Vennekens, Vasiliki, Michaki, Paul P, Van Veldhoven, Fabian, Feiguin, Bart, De Strooper, Carlos G, Dotti, Tina, Wahle
Publikováno v:
Aging cell. 11(1)
Several studies suggest that the generation of Aβ is highly dependent on the levels of cholesterol within membranes' detergent-resistant microdomains (DRM). Indeed, the β-amyloid precursor protein (APP) cleaving machinery, namely β- and γ-secreta