Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Vasiliki, Matzaraki"'
Autor:
Elise M. G. Meeder, Louise E. van Eekeren, Marc J. T. Blaauw, Albert L. Groenendijk, Wilhelm A. J. W. Vos, Jan van Lunzen, Leo A. B. Joosten, Mihai G. Netea, Quirijn de Mast, Willem L. Blok, Annelies Verbon, Marvin A. H. Berrevoets, Vasiliki Matzaraki, Andre J. A. M. van der Ven, Arnt F. A. Schellekens
Publikováno v:
Brain and Behavior, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Objectives Psychiatric symptoms occur frequently in people living with human immunodeficiency virus (PLWH), which may affect quality of life, sexual risk behavior, and adherence to antiretroviral therapy (ART). Data from large cohorts are li
Externí odkaz:
https://doaj.org/article/916e9c36853a42f28d8e1694cd645f45
Autor:
Maaike M.E. Jacobs, Rianne J.F. Maas, Inge Jonkman, Yutaka Negishi, Willem Tielemans Zamora, Cansu Yanginlar, Julia van Heck, Vasiliki Matzaraki, Joost H.A. Martens, Marijke Baltissen, Michiel Vermeulen, Judit Morla-Folch, Anna Ranzenigo, William Wang, Martin Umali, Jordi Ochando, Johan van der Vlag, Luuk B. Hilbrands, Leo A.B. Joosten, Mihai G. Netea, Willem J.M. Mulder, Mandy M.T. van Leent, Musa M. Mhlanga, Abraham J.P. Teunissen, Nils Rother, Raphaël Duivenvoorden
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114664- (2024)
Summary: Trained immunity is characterized by histone modifications and metabolic changes in innate immune cells following exposure to inflammatory signals, leading to heightened responsiveness to secondary stimuli. Although our understanding of the
Externí odkaz:
https://doaj.org/article/ad03aab3985e4aec8f638ad9ab1291e2
Autor:
Wilhelm A. J. W. Vos, Adriana Navas, Elise M. G. Meeder, Marc J. T. Blaauw, Albert L. Groenendijk, Louise E. van Eekeren, Twan Otten, Nadira Vadaq, Vasiliki Matzaraki, Bram van Cranenbroek, Kees Brinkman, Jan van Lunzen, Leo A. B. Joosten, Mihai G. Netea, Willem L. Blok, Andre J. A. M. van der Ven, Hans J. P. M. Koenen, Janneke E. Stalenhoef
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionImmunological non-responders (INR) are people living with HIV (PLHIV) who fail to fully restore CD4+ T-cell counts despite complete viral suppression with antiretroviral therapy (ART). INR are at higher risk for non-HIV related morbidity
Externí odkaz:
https://doaj.org/article/fe9f62a30ced4509bab65036784e5714
Autor:
Anaísa V. Ferreira, Juan Carlos Alarcon-Barrera, Jorge Domínguez-Andrés, Özlem Bulut, Gizem Kilic, Priya A. Debisarun, Rutger J. Röring, Hatice N. Özhan, Eva Terschlüsen, Athanasios Ziogas, Sarantos Kostidis, Yassene Mohammed, Vasiliki Matzaraki, George Renieris, Evangelos J. Giamarellos-Bourboulis, Mihai G. Netea, Martin Giera
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Infections and vaccines can induce enhanced long-term responses in innate immune cells, establishing an innate immunological memory termed trained immunity. Here, we show that monocytes with a trained immunity phenotype, due to exposure to t
Externí odkaz:
https://doaj.org/article/8d55ada0d53e44d18afec045e805fbf3
Autor:
Nils Rother, Cansu Yanginlar, Geoffrey Prévot, Inge Jonkman, Maaike Jacobs, Mandy M.T. van Leent, Julia van Heck, Vasiliki Matzaraki, Anthony Azzun, Judit Morla-Folch, Anna Ranzenigo, William Wang, Roy van der Meel, Zahi A. Fayad, Niels P. Riksen, Luuk B. Hilbrands, Rik G.H. Lindeboom, Joost H.A. Martens, Michiel Vermeulen, Leo A.B. Joosten, Mihai G. Netea, Willem J.M. Mulder, Johan van der Vlag, Abraham J.P. Teunissen, Raphaël Duivenvoorden
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113458- (2023)
Summary: Innate immune memory, also called ''trained immunity,'' is a functional state of myeloid cells enabling enhanced immune responses. This phenomenon is important for host defense, but also plays a role in various immune-mediated conditions. We
Externí odkaz:
https://doaj.org/article/dff74b8c0faf4120b0eff5cf97c0a2a4
Autor:
Wilhelm A. J. W. Vos, Nadira Vadaq, Vasiliki Matzaraki, Twan Otten, Albert L. Groenendijk, Marc J. T. Blaauw, Louise E. van Eekeren, Kees Brinkman, Quirijn de Mast, Niels P. Riksen, Anton F. H. Stalenhoef, Jan van Lunzen, Andre J. A. M. van der Ven, Willem L. Blok, Janneke E. Stalenhoef
Publikováno v:
Viruses, Vol 16, Iss 4, p 582 (2024)
In people living with HIV (PLHIV), integrase strand transfer inhibitors (INSTIs) are part of the first-line combination antiretroviral therapy (cART), while non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens are alternatives. Disti
Externí odkaz:
https://doaj.org/article/f709bcd454a146f98691dffd7cf32341
Autor:
Yue Zhang, Sergio Andreu-Sánchez, Nadira Vadaq, Daoming Wang, Vasiliki Matzaraki, Wouter A. van der Heijden, Ranko Gacesa, Rinse K. Weersma, Alexandra Zhernakova, Linos Vandekerckhove, Quirijn de Mast, Leo A. B. Joosten, Mihai G. Netea, André J. A. M. van der Ven, Jingyuan Fu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundPeople living with human immunodeficiency virus (PLHIV) are exposed to chronic immune dysregulation, even when virus replication is suppressed by antiretroviral therapy (ART). Given the emerging role of the gut microbiome in immunity, we hy
Externí odkaz:
https://doaj.org/article/95e0698f27d345e292c73b1565aa8964
Autor:
Nadira Vadaq, Yue Zhang, Wilhelm A.J.W. Vos, Albert L. Groenendijk, Martinus J.T. Blaauw, Louise E. van Eekeren, Maartje Jacobs-Cleophas, Lisa van de Wijer, Jéssica Cristina dos Santos, Muhammad Hussein Gasem, Leo A.B. Joosten, Mihai G. Netea, Quirijn de Mast, Jingyuan Fu, André J.A.M. van der Ven, Vasiliki Matzaraki
Publikováno v:
JCI Insight, Vol 8, Iss 11 (2023)
BACKGROUND People living with HIV (PLHIV) receiving antiretroviral therapy (ART) exhibit persistent immune dysregulation and microbial dysbiosis, leading to development of cardiovascular diseases (CVDs). We initially compared plasma proteomic profile
Externí odkaz:
https://doaj.org/article/2aec36f4e35b492a95622006f7e104dd
Autor:
Anaísa V. Ferreira, Sarantos Kostidis, Laszlo A. Groh, Valerie A.C.M. Koeken, Mariolina Bruno, Ilayda Baydemir, Gizem Kilic, Özlem Bulut, Theano Andriopoulou, Victoria Spanou, Kalliopi D. Synodinou, Theologia Gkavogianni, Simone J.C.F.M. Moorlag, L. Charlotte de Bree, Vera P. Mourits, Vasiliki Matzaraki, Werner J.H. Koopman, Frank L. van de Veerdonk, Georgios Renieris, Martin Giera, Evangelos J. Giamarellos-Bourboulis, Boris Novakovic, Jorge Domínguez-Andrés
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112658- (2023)
Summary: Itaconate is an immunomodulatory metabolite produced by immune cells under microbial stimulation and certain pro-inflammatory conditions and triggers antioxidant and anti-inflammatory responses. We show that dimethyl itaconate, a derivative
Externí odkaz:
https://doaj.org/article/6e7649ccdf4846afb0796f373689a5d6
Autor:
Louise E. van Eekeren, Vasiliki Matzaraki, Zhenhua Zhang, Lisa van de Wijer, Marc J. T. Blaauw, Marien I. de Jonge, Linos Vandekerckhove, Wim Trypsteen, Leo A. B. Joosten, Mihai G. Netea, Quirijn de Mast, Hans J. P. M. Koenen, Yang Li, André J. A. M. van der Ven
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract CCR5 is the main HIV co-receptor. We aimed to (1) compare CCR5 expression on immune cells between people living with HIV (PLHIV) using combination antiretroviral therapy (cART) and HIV-uninfected controls, (2) relate CCR5 expression to viral
Externí odkaz:
https://doaj.org/article/9d9df5a0e9dc4f38a2e4af830557c8ab