Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Vasilichia, Antoci"'
Autor:
Dumitrela Diaconu, Violeta Mangalagiu, Simona Dunca, Dorina Amariucai-Mantu, Vasilichia Antoci, Tiberiu Roman, Ionel I. Mangalagiu
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21518- (2023)
We present in this paper a direct and efficient study regarding synthesis and spectral characterization of three series of hybrid quinoline anchored with 4-R-benzenesulfonamide moiety, with potential antimicrobial activity, by using ultrasound (US) i
Externí odkaz:
https://doaj.org/article/2972a7cc586d442cab7b93353884990e
Autor:
Dumitrela Diaconu, Vasilichia Antoci, Violeta Mangalagiu, Dorina Amariucai-Mantu, Ionel I. Mangalagiu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Two new classes of hybrid quinoline–imidazole/benzimidazole derivatives (the hybrid QIBS salts and QIBC cycloadducts) were designed and synthesized to evaluate their anticancer and antimicrobial activity. The strategy adopted for synthesis
Externí odkaz:
https://doaj.org/article/b28e40a1ebc246db91ed5f4df3418514
Publikováno v:
Molbank, Vol 2021, Iss 3, p M1280 (2021)
We report here the design and synthesis of a new hybrid bis-anthracene-imidazolium salt, having a pyridine scaffold. NMR studies of dimer generation, as well as complexation with zinc acetate were performed.
Externí odkaz:
https://doaj.org/article/bb7488eccfc748f686ff95346449232c
Autor:
Vasilichia Antoci, Liliana Oniciuc, Dorina Amariucai-Mantu, Costel Moldoveanu, Violeta Mangalagiu, Andreea Madalina Amarandei, Claudiu N. Lungu, Simona Dunca, Ionel I. Mangalagiu, Gheorghita Zbancioc
Publikováno v:
Pharmaceuticals, Vol 14, Iss 4, p 335 (2021)
We report here the design, synthesis, experimental and in silico evaluation of the antibacterial and antifungal activity of some new benzo[f]quinoline derivatives. Two classes of benzo[f]quinolinium derivatives—(benzo[f]quinolinium salts (BQS) and
Externí odkaz:
https://doaj.org/article/337e7d876d59443287a3a09ba753522f
Publikováno v:
Molecules, Vol 25, Iss 19, p 4416 (2020)
We present herein a straightforward and efficient pathway for the synthesis of pyrrolophthalazine cycloadducts via Huisgen [3 + 2] dipolar cycloaddition reactions of phthalazinium ylides to methyl propiolate or dimethyl acetylenedicarboxylate (DMAD).
Externí odkaz:
https://doaj.org/article/c831d7e3125a4ece951e501524f53aeb
Autor:
Dumitrela Diaconu, Violeta Mangalagiu, Dorina Amariucai-Mantu, Vasilichia Antoci, Cristian Levente Giuroiu, Ionel I. Mangalagiu
Publikováno v:
Molecules, Vol 25, Iss 12, p 2946 (2020)
Two new series of hybrid quinoline-sulfonamide complexes (M2+: Zn2+, Cu2+, Co2+ and Cd2+) derivatives (QSC) were designed, synthesized and tested for their antimicrobial activity. The synthesis is straightforward and efficient, involving two steps: a
Externí odkaz:
https://doaj.org/article/1660e258854046358f584c268010cf22
Autor:
Costel Moldoveanu, Dorina Amariucai-Mantu, Violeta Mangalagiu, Vasilichia Antoci, Dan Maftei, Ionel I. Mangalagiu, Gheorghita Zbancioc
Publikováno v:
Molecules, Vol 24, Iss 20, p 3760 (2019)
We report here the synthesis and optical spectral properties of several new pyrrolodiazine derivatives. The luminescent heterocycles were synthesized by 1,3-dipolar cycloaddition reactions between N-alkylated pyridazine and methylpropiolate or dimeth
Externí odkaz:
https://doaj.org/article/e573825190e14b2182a765ededf2a1fa
Benzoquinoline Derivatives: An Attractive Approach to Newly Small Molecules with Anticancer Activity
Autor:
Liliana Oniciuc, Dorina Amăriucăi-Mantu, Dumitrela Diaconu, Violeta Mangalagiu, Ramona Danac, Vasilichia Antoci, Ionel I. Mangalagiu
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8124
This study presents the synthesis, structural characterization, and in vitro evaluation of anticancer activity of some newly benzo[f]quinoline derivatives. The synthesis is facile and efficient, involving two steps: quaternization of nitrogen heteroc
Autor:
Vasilichia Antoci, Ionel I. Mangalagiu, Maria Mirabela Grigore, Bogdan Ionel Bratanovici, Claudiu N. Lungu
Publikováno v:
Current Medicinal Chemistry. 27:154-169
Lack of specificity and subsequent therapeutic effectiveness of antimicrobial and antitumoral drugs is a common difficulty in therapy. The aim of this study is to investigate, both by experimental and computational methods, the antitumoral and antimi