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Autor:
K. G. Ravichandran, Ewa Skrzypczak-Jankun, Vasili E. Carperos, Mary L. Westbrook, Alexander Tulinsky, John M. Maraganore
Publikováno v:
Journal of Molecular Biology. 221:1379-1393
The isomorphous structures of the hirugen (N-acetylhirudin 53′-64′ with sulfato-Tyr63′) and hirulog 1 ( d -Phe-Pro-Arg-Pro-(Gly)4 desulfato-Tyr63′-hirugen) complexes of human α-thrombin have been determined and refined at 2.2Aresolution to c