Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vasileios Papalazarou"'
Autor:
Mattia Falcone, Alejandro Huerta Uribe, Vasileios Papalazarou, Alice C. Newman, Dimitris Athineos, Katrina Stevenson, Charles-Etienne Gabriel Sauvé, Yajing Gao, Jin K. Kim, Michael Del Latto, Maria Kierstead, Chao Wu, J. Joshua Smith, Paul B. Romesser, Anthony J. Chalmers, Karen Blyth, Oliver D. K. Maddocks
Publikováno v:
British Journal of Cancer. 127:1773-1786
Background Cellular metabolism is an integral component of cellular adaptation to stress, playing a pivotal role in the resistance of cancer cells to various treatment modalities, including radiotherapy. In response to radiotherapy, cancer cells enga
Autor:
Vasileios Papalazarou, James Drew, Amelie Juin, Heather J. Spence, Jamie Whitelaw, Colin Nixon, Manuel Salmeron-Sanchez, Laura M. Machesky
Peer reviewed: True
Funder: University of Glasgow; Id: http://dx.doi.org/10.13039/501100000853
Pancreatic cancer is a deadly and highly metastatic disease, although how metastatic lesions establish is not fully understood. A key feature of
Funder: University of Glasgow; Id: http://dx.doi.org/10.13039/501100000853
Pancreatic cancer is a deadly and highly metastatic disease, although how metastatic lesions establish is not fully understood. A key feature of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e39094168a55adf4f6c2542d02dacb9
Autor:
Vasileios Papalazarou, James Drew, Amelie Juin, Heather J. Spence, Colin Nixon, Manuel Salmeron-Sanchez, Laura M. Machesky
Pancreatic cancer is a deadly disease with high rates of metastasis, though how tumor cells establish metastatic lesions is not fully understood. A key feature of primary pancreatic tumors is extensive fibrosis due to deposition of extracellular matr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a64e7679e1f146eef86550d8168fac57
https://doi.org/10.1101/2022.03.03.482797
https://doi.org/10.1101/2022.03.03.482797
Nutrient supply and demand delineate cell behavior in health and disease. Mammalian cells have developed multiple strategies to secure the necessary nutrients that fuel their metabolic needs. This is more evident upon disruption of homeostasis in con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd66551003be60cec47d86fffa0897a
https://eprints.gla.ac.uk/250038/2/250038.pdf
https://eprints.gla.ac.uk/250038/2/250038.pdf
Autor:
Laura M. Machesky, Hans-Henning Arnold, Heather J. Spence, Vasileios Papalazarou, Klemens Rottner, Karthic Swaminathan, Ines Lahmann, Colin Nixon, Manuel Salmerón-Sánchez, Farah Jaber-Hijazi
Publikováno v:
Development (Cambridge, England)
England
article-version (VoR) Version of Record
England
article-version (VoR) Version of Record
The Arp2/3 complex is essential for the assembly of branched filamentous actin, but its role in physiology and development is surprisingly little understood. Melanoblasts deriving from the neural crest migrate along the developing embryo and traverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2daf30fbae3e38d5a622df5aa0c81fd3
https://eprints.gla.ac.uk/226709/1/226709.pdf
https://eprints.gla.ac.uk/226709/1/226709.pdf
Autor:
Colin Nixon, Steven Reid, Vasileios Papalazarou, Laura M. Machesky, Ewan J. McGhee, Lisa J. Neilson, David M. Bryant, Ralf H. Adams, Francesca Patella, Karthic Swaminathan, Sandeep Dhayade, Jens Serneels, Karen Blyth, Álvaro Román-Fernández, Shehab Ismail, Manuel Salmerón-Sánchez, Alice Santi, Massimiliano Mazzone, Sara Zanivan, Yasmin ElMaghloob, Emily J. Kay, Juan Ramon Hernandez-Fernaud, Leo M. Carlin, Dimitris Athineos, Anne Theres Henze, John B. G. Mackey
Publikováno v:
The EMBO Journal
Tumor progression alters the composition and physical properties of the extracellular matrix. Particularly, increased matrix stiffness has profound effects on tumor growth and metastasis. While endothelial cells are key players in cancer progression,
Publikováno v:
Biophysical Reviews
Mechanosensing is increasingly recognised as important for tumour progression. Tumours become stiff and the forces that normally balance in the healthy organism break down and become imbalanced, leading to increases in migration, invasion and metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a224153b26fa50ec917f538b93d12c
https://eprints.gla.ac.uk/171838/1/171838.pdf
https://eprints.gla.ac.uk/171838/1/171838.pdf
Autor:
Ewan J. McGhee, Laura M. Machesky, Karthic Swaminathan, Farah Jaber-Hijazi, Douglas Strathdee, Colin Nixon, Andrew D. Campbell, Owen J. Sansom, Vasileios Papalazarou
Publikováno v:
Journal of Investigative Dermatology. 141:628-637.e15
BRAFV600E is the most common driver mutation in human cutaneous melanoma and is frequently accompanied by loss of the tumor-suppressing phosphatase PTEN. Recent evidence suggests a co-operative role for RAC1 activity in BRAFV600E-driven melanoma prog