Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Vasileia Sapountzi"'
Antagonistic relationship of NuA4 with the non-homologous end-joining machinery at DNA damage sites.
Autor:
Salar Ahmad, Valérie Côté, Xue Cheng, Gaëlle Bourriquen, Vasileia Sapountzi, Mohammed Altaf, Jacques Côté
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009816 (2021)
The NuA4 histone acetyltransferase complex, apart from its known role in gene regulation, has also been directly implicated in the repair of DNA double-strand breaks (DSBs), favoring homologous recombination (HR) in S/G2 during the cell cycle. Here,
Externí odkaz:
https://doaj.org/article/91831aa9281044388e22d5c6c7481cc1
Autor:
Gaelle Bourriquen, Xue Cheng, Mohammed Altaf, Salar Ahmad, Jacques Côté, Vasileia Sapountzi, Valérie Côté
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009816 (2021)
PLoS Genetics
PLoS Genetics
The NuA4 histone acetyltransferase complex, apart from its known role in gene regulation, has also been directly implicated in the repair of DNA double-strand breaks (DSBs), favoring homologous recombination (HR) in S/G2 during the cell cycle. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855b875801f5443472db05eac158b4fa
https://doi.org/10.1101/2021.01.29.428810
https://doi.org/10.1101/2021.01.29.428810
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 40:236-244
Tat-interactive protein 60 kDa is a nuclear acetyltransferase that both coactivates and corepresses transcription factors and has a definitive function in the DNA damage response. Here, we provide evidence that Tat-interactive protein 60 kDa is phosp
Autor:
Ian R. Logan, Hing Y. Leung, Stuart McCracken, Luke Gaughan, Vasileia Sapountzi, Craig N. Robson
Publikováno v:
Molecular and Cellular Biology. 26:6502-6510
The androgen receptor (AR) is a hormone-dependent transcription factor critically involved in human prostate carcinogenesis. Optimal transcriptional control of androgen-responsive genes by AR may require complex interaction among multiple coregulator
Autor:
Craig N. Robson, Mingzhou Chen, Jean-Claude Cortay, Ian R. Logan, Vasileia Sapountzi, Denis Gerlier
Publikováno v:
Journal of Virology. 79:11824-11836
Using a C-terminal domain (PCT) of the measles virus (MV) phosphoprotein (P protein) as bait in a yeast two-hybrid screen, a cDNA identical to the recently described human p53-induced-RING-H2 (hPIRH2) cDNA was isolated. A glutathione S -transferase-h
Publikováno v:
Journal of Biological Chemistry. 279:11696-11704
Murine PIRH2 (mPIRH2) was recently identified as a RING finger-containing ubiquitin-protein isopeptide ligase that interacts with both p53 and the human androgen receptor. mpirh2 is a p53-responsive gene that is up-regulated by UV, and mPIRH2 protein
Publikováno v:
BioEssays. 24:350-361
The fascins are a structurally unique and evolutionarily conserved group of actin cross-linking proteins. Fascins function in the organisation of two major forms of actin-based structures: dynamic, cortical cell protrusions and cytoplasmic microfilam
Autor:
Michael J. Carrozza, Vasileia Sapountzi, Johnathan Chittuluru, Julie Monnet-Saksouk, Michael Fried, Jacques Côté, Stéphane Allard, Jerry L. Workman, Gang Cai, Jiehuan Huang, Rhea T. Utley, Francisco J. Asturias, Song Tan, Yuriy Chaban, William Selleck, Myriam Cramet
Publikováno v:
Nature structural & molecular biology
We have used EM and biochemistry to characterize the structure of NuA4, an essential yeast histone acetyltransferase (HAT) complex conserved throughout eukaryotes, and we have determined the interaction of NuA4 with the nucleosome core particle (NCP)
Autor:
Vasileia Sapountzi, Jacques Côté
Publikováno v:
Cellular and molecular life sciences : CMLS. 68(7)
Covalently modifying a protein has proven to be a powerful mechanism of functional regulation. N-epsilon acetylation of lysine residues was initially discovered on histones and has been studied extensively in the context of chromatin and DNA metaboli
Autor:
Paolo Plevani, James E. Haber, Vasileia Sapountzi, Granata M, Moreshwar B. Vaze, David Lydall, Marco Muzi-Falconi, Federico Lazzaro, Achille Pellicioli
Publikováno v:
The EMBO Journal
Cells respond to DNA double-strand breaks (DSBs) and uncapped telomeres by recruiting checkpoint and repair factors to the site of lesions. Single-stranded DNA (ssDNA) is an important intermediate in the repair of DSBs and is produced also at uncappe