Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Vasilatou, D."'
MicroRNA-92a-3p (miR-92a-3p) derives from the oncogenic miR-17/92 cluster and its highly homologous miR-106a/363 cluster. miR-92a-3p regulates the expression of key transcription factors such as HIF1 and inhibits SOCS1 to enhance the anti-apoptotic S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::d6efecd53f1847d912ea762656a2b26b
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3077855
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3077855
The demethylating factor 5-azacytidine (5-AZA) improves survival in intermediate-2 and high-risk myelodysplastic syndrome (MDS) patients [according to the International Prognostic Score System (IPSS)] responding to treatment. However, the outcome of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::224499392c34225e5bdf35d20b7ae8bd
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086564
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086564
MicroRNA-20b-5p (miR-20b-5p) is part of the miR-106a/363 cluster and a member of the cancer-related miR-17 family. miR-20b-5p regulates important transcription factors, including hypoxia-inducible factor 1 (HIF1) and signal transducer and activator o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::a218a3e531a35c15bdab48e6b9d83f40
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086189
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086189
In this study, we investigated the incidence and prognostic impact of monosomal karyotype (MK) in 405 higher-risk Myelodysplastic Syndromes (MDS) patients treated with 5-AZA. The MK was present in 66 out of 405 (16.3%) patients, most of whom had comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::8c977081807354576443849bb9bd354f
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3107292
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3107292
The hypoxia inducible factor 1 (HIF1) is a heterodimeric transcription factor that ultimately regulates cellular responses to changes in oxygen tension. In this study, we examined the potential diagnostic and prognostic potential of the mRNA expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::475e8cd18a0db047fa6f3f0a7408800b
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086359
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086359
Accumulated data indicate a significant role of T cell dysfunction in the pathogenesis of chronic lymphocytic leukemia. In CLL, regulatory T cells are significantly higher and show lower apoptotic levels compared to healthy donors. We demonstrate tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::7e5f3b62b28b3bdadece6bd1240b9c54
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086665
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086665
Mycosis fungoides (MF) and its leukemic variant Sézary syndrome (SS) comprise the majority of CTCL, a heterogenous group of non-Hodgkins lymphomas involving the skin. The CTCL's resistance to chemotherapy and the lack of full understanding of their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::0b26b5a9cd9ce3f28e4f1b60e8e0ac83
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056740
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056740
Objectives: The demethylating factor 5-Azacytidine (5-AZA) improves survival of patients with myelodysplastic syndromes (MDS) in randomized control trials but the results in 'real life' are controversial. Methods: In this retrospective study, we eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::0e4a540ed5669173b1168b7347f19187
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3101357
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3101357
miRNAs are small noncoding RNAs that regulate gene expression at the post-transcriptional level. Since their discovery, miRNAs have been associated with every cell function including malignant transformation and metastasis. Endometrial cancer is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::50b75281653c053c81dd271055b6c34d
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3088252
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3088252