Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vasil D'Ambrosio"'
Autor:
Vasil D'Ambrosio, Lea G. Hansen, Jie Zhang, Emil D. Jensen, Dushica Arsovska, Marcos Laloux, Tadas Jakočiūnas, Pernille Hjort, Davide De Lucrezia, Serena Marletta, Jay D. Keasling, Michael K. Jensen
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 2, Pp 657-663 (2022)
The synthetic biology toolkit for baker's yeast, Saccharomyces cerevisiae, includes extensive genome engineering toolkits and parts repositories. However, with the increasing complexity of engineering tasks and versatile applications of this model eu
Externí odkaz:
https://doaj.org/article/350328b816f64150aa8b75abe0b35547
Autor:
Vasil, D'Ambrosio, Lea G, Hansen, Jie, Zhang, Emil D, Jensen, Dushica, Arsovska, Marcos, Laloux, Tadas, Jakočiūnas, Pernille, Hjort, Davide, De Lucrezia, Serena, Marletta, Jay D, Keasling, Michael K, Jensen
Publikováno v:
Synthetic and systems biotechnology. 7(2)
The synthetic biology toolkit for baker's yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33576808ca80324cbc7230692cb35284
https://pubmed.ncbi.nlm.nih.gov/35224233
https://pubmed.ncbi.nlm.nih.gov/35224233
Autor:
Jie Zhang, Lea G. Hansen, Olga Gudich, Konrad Viehrig, Lærke M. M. Lassen, Lars Schrübbers, Khem B. Adhikari, Paulina Rubaszka, Elena Carrasquer-Alvarez, Ling Chen, Vasil D’Ambrosio, Beata Lehka, Ahmad K. Haidar, Saranya Nallapareddy, Konstantina Giannakou, Marcos Laloux, Dushica Arsovska, Marcus A. K. Jørgensen, Leanne Jade G. Chan, Mette Kristensen, Hanne B. Christensen, Suresh Sudarsan, Emily A. Stander, Edward Baidoo, Christopher J. Petzold, Tune Wulff, Sarah E. O’Connor, Vincent Courdavault, Michael K. Jensen, Jay D. Keasling
Publikováno v:
Nature
Zhang, J, Hansen, L G, Gudich, O, Viehrig, K, Lassen, L M M, Schrübbers, L, Adhikari, K B, Rubaszka, P, Carrasquer-Alvarez, E, Chen, L, D’Ambrosio, V, Lehka, B, Haidar, A K, Nallapareddy, S, Giannakou, K, Laloux, M, Arsovska, D, Jørgensen, M A K, Chan, L J G, Kristensen, M, Christensen, H B, Sudarsan, S, Stander, E A, Baidoo, E, Petzold, C J, Wulff, T, O’Connor, S E, Courdavault, V, Jensen, M K & Keasling, J D 2022, ' A microbial supply chain for production of the anti-cancer drug vinblastine ', Nature, vol. 609, no. 7926, pp. 341-347 . https://doi.org/10.1038/s41586-022-05157-3
Nature, vol 609, iss 7926
Zhang, J, Hansen, L G, Gudich, O, Viehrig, K, Lassen, L M M, Schrübbers, L, Adhikari, K B, Rubaszka, P, Carrasquer-Alvarez, E, Chen, L, D’Ambrosio, V, Lehka, B, Haidar, A K, Nallapareddy, S, Giannakou, K, Laloux, M, Arsovska, D, Jørgensen, M A K, Chan, L J G, Kristensen, M, Christensen, H B, Sudarsan, S, Stander, E A, Baidoo, E, Petzold, C J, Wulff, T, O’Connor, S E, Courdavault, V, Jensen, M K & Keasling, J D 2022, ' A microbial supply chain for production of the anti-cancer drug vinblastine ', Nature, vol. 609, no. 7926, pp. 341-347 . https://doi.org/10.1038/s41586-022-05157-3
Nature, vol 609, iss 7926
Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary metabolites with many medicinal properties, including the essential anti-cancer therapeutics vinblastine and vincristine1. As MIAs are difficult to chemically synthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bacac052957ae55ba7af120ea83ec4
https://pubmed.ncbi.nlm.nih.gov/36370691
https://pubmed.ncbi.nlm.nih.gov/36370691
Autor:
Irina Borodina, Behrooz Darbani, Vasil D'ambrosio, Guokun Wang, Iben Møller-Hansen, Michael Krogh Jensen, Hanne Bjerre Christensen, Mahsa Babaei
Publikováno v:
Wang, G, Møller-Hansen, I, Babaei, M, D'Ambrosio, V, Christensen, H B, Darbani, B, Jensen, M K & Borodina, I 2021, ' Transportome-wide engineering of Saccharomyces cerevisiae ', Metabolic Engineering, vol. 64, pp. 52-63 . https://doi.org/10.1016/j.ymben.2021.01.007
Metabolic Engineering
Metabolic Engineering
Synthetic biology enables the production of small molecules by recombinant microbes for pharma, food, and materials applications. The secretion of products reduces the cost of separation and purification, but it is challenging to engineer due to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee9000518e9ee65f3125246bfaaedc8
https://orbit.dtu.dk/en/publications/cbd33886-38d5-435f-909a-b6b35607bac1
https://orbit.dtu.dk/en/publications/cbd33886-38d5-435f-909a-b6b35607bac1
Autor:
Michael Krogh Jensen, Morten Otto Alexander Sommer, Jay D. Keasling, Robert Mans, Jolanda ter Horst, Francesca Ambri, Roberto Di Blasi, Vasil D'ambrosio, Marcel van den Broek, Eleonora Dore, Peter Rugbjerg, Suresh Sudarsan
Publikováno v:
Metabolic Engineering, 61
D'ambrosio, V, Dore, E, Di Blasi, R, van den Broek, M, Sudarsan, S, ter Horst, J, Ambri, F, Sommer, M O A, Rugbjerg, P, Keasling, J D, Mans, R & Jensen, M K 2020, ' Regulatory control circuits for stabilizing long-term anabolic product formation in yeast ', Metabolic Engineering, vol. 61, pp. 369-380 . https://doi.org/10.1016/j.ymben.2020.07.006
Metabolic Engineering
D'ambrosio, V, Dore, E, Di Blasi, R, van den Broek, M, Sudarsan, S, ter Horst, J, Ambri, F, Sommer, M O A, Rugbjerg, P, Keasling, J D, Mans, R & Jensen, M K 2020, ' Regulatory control circuits for stabilizing long-term anabolic product formation in yeast ', Metabolic Engineering, vol. 61, pp. 369-380 . https://doi.org/10.1016/j.ymben.2020.07.006
Metabolic Engineering
Engineering living cells for production of chemicals, enzymes and therapeutics can burden cells due to use of limited native co-factor availability and/or expression burdens, totalling a fitness deficit compared to parental cells encoded through long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d97db74f5f9544ff063354d4e32b0d86
https://escholarship.org/uc/item/0cg460bm
https://escholarship.org/uc/item/0cg460bm
Autor:
Simo Abdessamad Baallal Jacobsen, Douglas McCloskey, Francesca Ambri, Vasil D'ambrosio, Jay D. Keasling, Jerome Maury, Roberto Di Blasi, Michael Krogh Jensen
Publikováno v:
ACS synthetic biology, vol 9, iss 2
Ambri, F, D'ambrosio, V, Di Blasi, R, Maury, J, Baallal Jacobsen, S A, McCloskey, D, Jensen, M K & Keasling, J D 2020, ' High-resolution scanning of optimal biosensor reporter promoters in yeast ', ACS Synthetic Biology, vol. 9, no. 2, pp. 218-226 . https://doi.org/10.1021/acssynbio.9b00333
Ambri, F, D'ambrosio, V, Di Blasi, R, Maury, J, Baallal Jacobsen, S A, McCloskey, D, Jensen, M K & Keasling, J D 2020, ' High-resolution scanning of optimal biosensor reporter promoters in yeast ', ACS Synthetic Biology, vol. 9, no. 2, pp. 218-226 . https://doi.org/10.1021/acssynbio.9b00333
Small-molecule binding allosteric transcription factors (aTFs) derived from bacteria enable real-time monitoring of metabolite abundances, high-throughput screening of genetic designs, and dynamic control of metabolism. Yet, engineering of reporter p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e1662d3644cd0611db40acc6658abd
https://escholarship.org/uc/item/4d10205b
https://escholarship.org/uc/item/4d10205b
Autor:
Vasil D'ambrosio, Michael Krogh Jensen
Publikováno v:
FEMS Yeast Research
D'ambrosio, V & Jensen, M K 2017, ' Lighting up yeast cell factories by transcription factor-based biosensors ', FEMS Yeast Research, vol. 17, no. 7, fox076 . https://doi.org/10.1093/femsyr/fox076
D'ambrosio, V & Jensen, M K 2017, ' Lighting up yeast cell factories by transcription factor-based biosensors ', FEMS Yeast Research, vol. 17, no. 7, fox076 . https://doi.org/10.1093/femsyr/fox076
Our ability to rewire cellular metabolism for the sustainable production of chemicals, fuels and therapeutics based on microbial cell factories has advanced rapidly during the last two decades. Especially the speed and precision by which microbial ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ee22b21500fbd6970f78dcf1097cbb
https://pubmed.ncbi.nlm.nih.gov/28961766
https://pubmed.ncbi.nlm.nih.gov/28961766
Autor:
Kati Goroncy, Jay D. Keasling, Mehdi D. Davari, Subrata Pramanik, Michael Krogh Jensen, Vasil D'ambrosio, David Schönauer, Tadas Jakočiūnas, Ulrich Schwaneberg
Publikováno v:
Biotechnology Notes
Biotechnology notes 1, 9-15 (2020). doi:10.1016/j.biotno.2020.01.002
Biotechnology notes 1, 9-15 (2020). doi:10.1016/j.biotno.2020.01.002
Allosterically regulated transcription factors (aTFs) based biosensors from prokaryotes have been widely used to screen large gene libraries, stabilize engineered microbes from evolutionary drifting, and for detection of soil pollutants, among many o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d3ba0c4ef41ad96cb46b70ec8a936c