Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Vasculostatin"'
Publikováno v:
Cancers, Vol 13, Iss 3562, p 3562 (2021)
Cancers
Cancers
Simple Summary Brain-specific angiogenesis inhibitor 1 (BAI1) is a transmembrane adhesion GPCR protein that plays an important role in many cellular processes and functions. The ability of BAI1 to promote anti-tumor and anti-angiogenic effects has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da2dea952bdb921bf0c1157a726c5ed
https://www.mdpi.com/2072-6694/13/14/3562
https://www.mdpi.com/2072-6694/13/14/3562
Akademický článek
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Publikováno v:
Oncology Research
Osteosarcomas, especially those with metastatic or unresectable disease, have limited treatment options. The antitumor effects of pharmacologic inhibitors of angiogenesis in osteosarcomas are hampered in patients by the rapid development of tumor res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475e966752b741514d7ff246ed54f6b4
http://europepmc.org/articles/PMC7848452
http://europepmc.org/articles/PMC7848452
Autor:
Mitra Nair, Matthew O. Old, Chelsea Bolyard, Jun-Ge Yu, Raphael E. Pollock, Gonzalo Lopez, Yoshihiro Otani, Yeshavanth Kumar Banasavadi-Siddegowda, Balveen Kaur, Ji Young Yoo, Tae Jin Lee, Maninder Khosla, Jin Muk Kang, Margaret Yeh, Toshihiko Shimizu, Flora Park
Publikováno v:
Cancers, Vol 12, Iss 1040, p 1040 (2020)
Cancers
Volume 12
Issue 4
Cancers
Volume 12
Issue 4
Vascularization is a common pathology for many solid tumors, and therefore anti-angiogenic strategies are being investigated as a therapeutic target for treatment. Numerous studies are also being conducted regarding the effects of oncolytic viruses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50b14b7320222f30ec793bfd08a517c
https://www.mdpi.com/2072-6694/12/4/1040
https://www.mdpi.com/2072-6694/12/4/1040
Akademický článek
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Autor:
Eric M. Sandberg, E. G. Van Meir, Narra S. Devi, Balveen Kaur, Sarah M. Cork, Joel H. Saltz, Lee Cooper, Stefan Kaluz
Publikováno v:
Oncogene
Brain-specific angiogenesis inhibitor 1 (BAI1), an orphan G protein-coupled receptor-type seven transmembrane protein, was recently found mutated or silenced in multiple human cancers and can interfere with tumor growth when overexpressed. Yet, littl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500e0bba30f7e6283ae695ac3df9fcc9
https://doi.org/10.1038/onc.2012.1
https://doi.org/10.1038/onc.2012.1
Publikováno v:
Neuroscience letters. 527(2)
More than four decades ago, Dr. Judah Folkman hypothesized that angiogenesis was a critical process in tumor growth. Since that time, there have been significant advances in understanding tumor biology and groundbreaking research in cancer therapy th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da896b5d6f5fb08d03bc24e8d1f459a
https://pubmed.ncbi.nlm.nih.gov/22906922
https://pubmed.ncbi.nlm.nih.gov/22906922
Autor:
Erwin G. Van Meir, Philip A. Klenotic, Roy L. Silverstein, Balveen Kaur, Juan Palomo, Maria Febbraio, Candece L. Gladson, Michael A. Vogelbaum, Ping Huang
Publikováno v:
The American journal of pathology. 176(4)
Brain angiogenesis inhibitor 1 (BAI1) is a transmembrane protein expressed on glial cells within the brain. Its expression is dramatically down-regulated in many glioblastomas, consistent with its functional ability to inhibit angiogenesis and tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4404c57380f2d9755b5088f86bbcdaad
https://pubmed.ncbi.nlm.nih.gov/20167858
https://pubmed.ncbi.nlm.nih.gov/20167858
Autor:
Maria Febbraio, Zhaobin Zhang, Roy L. Silverstein, Daniel J. Brat, Sarah M. Cork, Balveen Kaur, Hui Mao, Carol Tucker-Burden, Hyunsuk Shim, Erwin G. Van Meir, Philip A. Klenotic, Jeffrey J. Olson, Eric M. Sandberg, Narra S. Devi
Angiogenesis is a critical physiologic process that is appropriated during tumorigenesis. Little is known about how this process is specifically regulated in the brain. Brain angiogenesis inhibitor-1 (BAI1) is a brain-predominant seven-transmembrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8023545ef13fcf5a6f0601bc23ee0afe
https://europepmc.org/articles/PMC2659670/
https://europepmc.org/articles/PMC2659670/
Publikováno v:
Oncogene. 24(22)
Brain angiogenesis inhibitor 1 (BAI1) is a transmembrane protein with unknown function expressed primarily in normal but not tumoral brain. The finding of thrombospondin type 1 repeats in its extracellular domain suggested an antiangiogenic function,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6a586647b6b20b0307252ed1d5ff95
https://pubmed.ncbi.nlm.nih.gov/15782143
https://pubmed.ncbi.nlm.nih.gov/15782143