Zobrazeno 1 - 10
of 1 400
pro vyhledávání: '"Vascular leakage"'
Autor:
Yue Zhang, Xiao-Jing Liu, Xin-Ran Zhai, Yao Yao, Bin Shao, Yu-Han Zhen, Xin Zhang, Zhe Xiao, Li-Fang Wang, Ming-Lian Zhang, Zhi-Min Chen
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 8, Pp 1403-1410 (2024)
AIM: To investigate the effects of fibrillin-1 (FBN1) deletion on the integrity of retina-blood barrier function and the apoptosis of vascular endothelial cells under diabetic conditions. METHODS: Streptozotocin (STZ)-induced diabetic mice were used
Externí odkaz:
https://doaj.org/article/13b7fd72c9084c90b45e94ab0247aecf
Autor:
Jiang Yu, Boying Zhao, Qiangzhong Pi, Guoxiang Zhou, Zhe Cheng, Can Qu, Xiaowen Wang, Lingwen Kong, Suxin Luo, Dingyuan Du, Yongzheng Guo
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background We have reported a positive correlation between S100 calcium-binding protein (S100) A8/S100A9 and sepsis-induced lung damage before. However, limited knowledge exists concerning the biological role of S100A8/A9 in pulmonary vascul
Externí odkaz:
https://doaj.org/article/a93a74e845ff4019adc4306a7ca82d42
Autor:
Takeshi Kurosu, Yusuke Sakai, Yasusi Ami, Masayuki Shimojima, Tomoki Yoshikawa, Shuetsu Fukushi, Noriyo Nagata, Tadaki Suzuki, Hideki Ebihara, Masayuki Saijo
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionSevere dengue is thought to be caused by an excessive host immune response.MethodsTo study the pathogenesis of severe dengue, we developed a novel model using LysM Cre+Ifnarflox/flox mice carrying depleted Ifnar expression only in subsets
Externí odkaz:
https://doaj.org/article/7d059a7697224f6f8a487686383ff71f
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 2, Pp n/a-n/a (2024)
Abstract Increased pulmonary vascular permeability is a characteristic feature of lung injury. However, there are no established methods that allow the three‐dimensional visualization and quantification of pulmonary vascular permeability in vivo. E
Externí odkaz:
https://doaj.org/article/72aa70adb1c14b4d897625f0d3e881b8
Autor:
Emmanuelle Guérin, Lisa Belin, Guillaume Franchineau, Loïc Le Guennec, David Hajage, Mamadou Hassimiou Diallo, Thomas Frapard, Lucie Le Fèvre, Charles-Edouard Luyt, Alain Combes, Stéphane Germain, Jan Hayon, Pierre Asfar, Nicolas Bréchot
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-11 (2023)
Abstract Background Vascular leakage is a major feature of acute respiratory distress syndrome (ARDS). We aimed to evaluate the efficacy of FX06, a drug under development that stabilizes interendothelial cell junctions, at reducing vascular leakage d
Externí odkaz:
https://doaj.org/article/7d0ee03f3545421d8d48646355d062b0
Autor:
Zhangwanyu Wei, Zhikun Yang, Donghui Li, Xiao Zhang, Bing Li, Xufeng Zhao, Wenyu Yan, Bingxuan Wu, Na Wu, Xuqian Wang, Weihong Yu, Min Shen
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-7 (2023)
Abstract Purpose To determine whether the rare NLRP3-Associated Autoinflammatory Disease (NLRP3-AID) is associated with retinal changes and to assess the ocular involvement. Methods A retrospective cohort study of 20 patients(40 eyes) diagnosed with
Externí odkaz:
https://doaj.org/article/6a805b46f6da453d8daed4371d9eaa8a
Autor:
Hye-Yoon Jeon, Chan-Hee Moon, Eun-Bin Kim, Nilofar Danishmalik Sayyed, Ah-Jun Lee, Kwon-Soo Ha
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Hyperglycemic memory (HGM) is a pivotal phenomenon in the development of diabetic complications. Although coincident diabetic complications are reported, research on their development and treatment is limited. Thus, we investigate
Externí odkaz:
https://doaj.org/article/96d415a8f7574579bceb56acaf2bc3a8
Autor:
Miesje M van der Stoel, Maria P Kotini, Rianne M Schoon, Markus Affolter, Heinz-Georg Belting, Stephan Huveneers
Publikováno v:
Vascular Biology, Vol 5, Iss 1, Pp 1-10 (2023)
Remodelling of cell–cell junctions is crucial for proper tissue development and barrier function. The cadherin-based adherens junctions anchor via β-catenin and α-catenin to the actomyosin cytoskeleton, together forming a junctional mechanotransd
Externí odkaz:
https://doaj.org/article/c1f45397219049b1abc631336bfcb371
Shear stress control of vascular leaks and atheromas through Tie2 activation by VE‐PTP sequestration
Autor:
Keisuke Shirakura, Peter Baluk, Astrid F Nottebaum, Ute Ipe, Kevin G Peters, Donald M McDonald, Dietmar Vestweber
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract Vascular endothelial protein tyrosine phosphatase (VE‐PTP) influences endothelial barrier function by regulating the activation of tyrosine kinase receptor Tie2. We determined whether this action is linked to the development of atheroscler
Externí odkaz:
https://doaj.org/article/6fec18acacae4392945db5159ce762d7
Autor:
Devy Deliyanti, Varaporn Suphapimol, Phoebe Ang, Xiuying Tang, Abhirup Jayasimhan, Jennifer L. Wilkinson-Berka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15680 (2023)
Retinal inflammation is a central feature of ocular neovascular diseases such as diabetic retinopathy and retinopathy of prematurity, but the contribution of neutrophils to this process is not fully understood. We studied oxygen-induced retinopathy (
Externí odkaz:
https://doaj.org/article/88843de44a5e490b9a9d798a4625a338