Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Vascular heterogeneity"'
Publikováno v:
Vascular Biology, Vol 6, Iss 1, Pp 1-15 (2024)
Endothelial cells (ECs) of blood and lymphatic vessels have distinct identity markers that define their specialized functions. Recently, hybrid vasculatures with both blood and lymphatic vessel-specific features have been discovered in multiple tissu
Externí odkaz:
https://doaj.org/article/63461bef0c054ce58c8ba7cab392f484
Autor:
Sheridan M Sargent, Stephanie K Bonney, Yuandong Li, Stefan Stamenkovic, Marc M Takeno, Vanessa Coelho-Santos, Andy Y Shih
Publikováno v:
Vascular Biology, Vol 5, Iss 10, Pp 1-12 (2023)
The high metabolic demand of brain tissue is supported by a constant supply of blood flow through dense microvascular networks. Capillaries are the smallest class of vessels in the brain and their lumens vary in diameter between ~2 and 5 μm. This di
Externí odkaz:
https://doaj.org/article/411f3700b2a449b7a7d1f2b79e710777
Autor:
Sweta Parab, Olivia A Card, Qiyu Chen, Michelle America, Luke D Buck, Rachael E Quick, William F Horrigan, Gil Levkowitz, Benoit Vanhollebeke, Ryota L Matsuoka
Publikováno v:
eLife, Vol 12 (2023)
Fenestrated and blood-brain barrier (BBB)-forming endothelial cells constitute major brain capillaries, and this vascular heterogeneity is crucial for region-specific neural function and brain homeostasis. How these capillary types emerge in a brain
Externí odkaz:
https://doaj.org/article/62c0001578584539bd3fbebb88f27cca
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Neoadjuvant chemotherapy (NAC) is widely accepted as a primary treatment for inoperable or locally advanced breast cancer before definitive surgery. However, not all advanced breast cancers are sensitive to NAC. Contrast-enhanced ultrasonography (CEU
Externí odkaz:
https://doaj.org/article/6f0933ab62c04a089ab935f594d137e5
Autor:
Molly C. McCloskey, Victor Z. Zhang, S. Danial Ahmad, Samuel Walker, Samantha S. Romanick, Hani A. Awad, James L. McGrath
Publikováno v:
Frontiers in Medical Technology, Vol 4 (2022)
The vascular system plays a critical role in the progression and resolution of inflammation. The contributions of the vascular endothelium to these processes, however, vary with tissue and disease state. Recently, tissue chip models have emerged as p
Externí odkaz:
https://doaj.org/article/1d80af8fb7f54b139a781ccb8eb257fa
Akademický článek
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Autor:
Colin M Cleary, Thiago S Moreira, Ana C Takakura, Mark T Nelson, Thomas A Longden, Daniel K Mulkey
Publikováno v:
eLife, Vol 9 (2020)
Respiratory chemoreceptors regulate breathing in response to changes in tissue CO2/H+. Blood flow is a fundamental determinant of tissue CO2/H+, yet little is known regarding how regulation of vascular tone in chemoreceptor regions contributes to res
Externí odkaz:
https://doaj.org/article/9ff7d9f1713040c0874ea849ac4d4a7e
Autor:
Yuliang He, Carlotta Tacconi, Lothar C. Dieterich, Jihye Kim, Gaetana Restivo, Epameinondas Gousopoulos, Nicole Lindenblatt, Mitchell P. Levesque, Manfred Claassen, Michael Detmar
Publikováno v:
Cells, Vol 11, Iss 7, p 1111 (2022)
Ample evidence pinpoints the phenotypic diversity of blood vessels (BVs) and site-specific functions of their lining endothelial cells (ECs). We harnessed single-cell RNA sequencing (scRNA-seq) to dissect the molecular heterogeneity of blood vascular
Externí odkaz:
https://doaj.org/article/0401a06346944fe5bf2bedde326778e3
Publikováno v:
Bioengineering & Translational Medicine, Vol 4, Iss 3, Pp n/a-n/a (2019)
Abstract Vascular diversity among organs has recently become widely recognized. Several studies using mouse and human fetal tissues revealed distinct characteristics of organ‐specific vasculature in molecular and functional levels. Thorough underst
Externí odkaz:
https://doaj.org/article/3509886a49f14d8c9df695721c4c0e96
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The blood–brain barrier (BBB) helps maintain a tightly regulated microenvironment for optimal central nervous system (CNS) homeostasis and facilitates communications with the peripheral circulation. The brain endothelial cells, lining the brain’s
Externí odkaz:
https://doaj.org/article/e45ec277d40442e0a4d71f1d563805e0