Zobrazeno 1 - 10
of 25 764
pro vyhledávání: '"Vascular Permeability"'
Autor:
Jung Won Kwon, Kihwang Lee, Sang Wha Kim, Jisu Park, Jung Joo Hong, Jeong-Hwan Che, Seung Hyeok Seok
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Diabetic retinopathy (DR) is a prevalent complication of diabetes, often resulting in vision loss and blindness. Existing treatments primarily aim to control blood sugar levels and inhibit angiogenesis. However, current therapies for DR, suc
Externí odkaz:
https://doaj.org/article/e057b41357284768b4a61dddc1045013
Autor:
Lorenz L. Mihatsch, Patrick Friederich
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The pulmonary vascular permeability index (PVPI) is a quotient of the extravascular lung water (EVLW) and the pulmonary blood volume (PBV). In acute respiratory distress syndrome (ARDS), the alveolar-capillary membrane integrity is disrupted
Externí odkaz:
https://doaj.org/article/0aeae04b2faf4f128c1195632d6abf4a
Autor:
Yue Zhang, Xiao-Jing Liu, Xin-Ran Zhai, Yao Yao, Bin Shao, Yu-Han Zhen, Xin Zhang, Zhe Xiao, Li-Fang Wang, Ming-Lian Zhang, Zhi-Min Chen
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 8, Pp 1403-1410 (2024)
AIM: To investigate the effects of fibrillin-1 (FBN1) deletion on the integrity of retina-blood barrier function and the apoptosis of vascular endothelial cells under diabetic conditions. METHODS: Streptozotocin (STZ)-induced diabetic mice were used
Externí odkaz:
https://doaj.org/article/13b7fd72c9084c90b45e94ab0247aecf
Autor:
Takahiro Akamine, Takeshi Terabayashi, Takako Sasaki, Riku Hayashi, Ichitaro Abe, Fumihiro Hirayama, Shin‐ichi Nureki, Masahito Ikawa, Haruhiko Miyata, Akinori Tokunaga, Takashi Kobayashi, Katsuhiro Hanada, Dean Thumkeo, Shuh Narumiya, Toshimasa Ishizaki
Publikováno v:
FEBS Open Bio, Vol 14, Iss 6, Pp 906-921 (2024)
The Ras homology (Rho) family of GTPases serves various functions, including promotion of cell migration, adhesion, and transcription, through activation of effector molecule targets. One such pair of effectors, the Rho‐associated coiled‐coil kin
Externí odkaz:
https://doaj.org/article/55c8cc91eaf9494c8af4f125e026844e
Autor:
Armando Montoya-Garcia, Idaira M Guerrero-Fonseca, Sandra D Chanez-Paredes, Karina B Hernandez-Almaraz, Iliana I Leon-Vega, Angelica Silva-Olivares, Abigail Betanzos, Monica Mondragon-Castelan, Ricardo Mondragon-Flores, Citlaltepetl Salinas-Lara, Hilda Vargas-Robles, Michael Schnoor
Publikováno v:
eLife, Vol 12 (2024)
Arpin was discovered as an inhibitor of the Arp2/3 complex localized at the lamellipodial tip of fibroblasts, where it regulated migration steering. Recently, we showed that arpin stabilizes the epithelial barrier in an Arp2/3-dependent manner. Howev
Externí odkaz:
https://doaj.org/article/de0546e6962e4806911a827825146387
Publikováno v:
Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101814- (2024)
Background: Vascular endothelial growth factor (VEGF) is one of the proteins involved in dengue immunopathogenesis. It is overexpressed in severe dengue and contributes to vascular permeability and plasma leakage. In this study, we investigated the e
Externí odkaz:
https://doaj.org/article/2a7732f7b1484fb3b195922a562ec15b
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-22 (2024)
Abstract Obesity, a burgeoning global health issue, is increasingly recognized for its detrimental effects on the central nervous system, particularly concerning the integrity of the blood-brain barrier (BBB). This manuscript delves into the intricat
Externí odkaz:
https://doaj.org/article/eae1e0202601480e8549bc7bafe88808
Autor:
Aurélie Joussaume, Chryso Kanthou, Olivier E. Pardo, Lucie Karayan-Tapon, Omar Benzakour, Fatima Dkhissi
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 3278-3293 (2024)
Protein S (PROS1) is a vitamin K-dependent anticoagulant factor, which also acts as an agonist for the TYRO3, AXL, and MERTK (TAM) tyrosine kinase receptors. PROS1 is produced by the endothelium which also expresses TAM receptors, but little is known
Externí odkaz:
https://doaj.org/article/7eb8813ce6a24d078a0b98f358bbfe47
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 03, Pp 16-20 (2024)
Introduction: Diabetes Mellitus (DM) is the most common noncommunicable disease and the fifth leading cause of death worldwide. Recent research has demonstrated that low Vitamin D levels and high Vascular Endothelial Growth Factor (VEGF) in middle-ag
Externí odkaz:
https://doaj.org/article/675016494f1a45feaebf4347a0e124c5
Autor:
Yiyan Liu, Daiqin Bao, Han She, Zisen Zhang, Shifeng Shao, Zhengbin Wu, Yue Wu, Qinghui Li, Li Wang, Tao Li, Liangming Liu
Publikováno v:
Redox Biology, Vol 78, Iss , Pp 103353- (2024)
Sepsis is a critical condition characterized by a systemic inflammatory response to infection, often leading to severe vascular dysfunction and high mortality. One of the hallmarks of vascular dysfunction in sepsis is increased vascular permeability
Externí odkaz:
https://doaj.org/article/f2acccd5413844208e2e6084ef6f8341