Zobrazeno 1 - 10
of 3 076
pro vyhledávání: '"Vascular Endothelial Growth Factor Receptor"'
Autor:
Min Guo, Junhao Zhang, Jiang Han, Yingyue Hu, Hao Ni, Juan Yuan, Yang Sun, Meijuan Liu, Lifen Gao, Wangjun Liao, Chunhong Ma, Yaou Liu, Shuijie Li, Nailin Li
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Glioblastoma is an aggressive brain tumor linked to significant angiogenesis and poor prognosis. Anti-angiogenic therapies with vascular endothelial growth factor receptor 2 (VEGFR2) inhibition have been investigated as an alterna
Externí odkaz:
https://doaj.org/article/712e2c19a1cc46c991715955dd112874
Autor:
Alexander Kirdeev, Konstantin Burkin, Anton Vorobev, Elena Zbirovskaya, Galina Lifshits, Konstantin Nikolaev, Elena Zelenskaya, Maxim Donnikov, Lyudmila Kovalenko, Irina Urvantseva, Maria Poptsova
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundThe development of prognostic models for the identification of high-risk myocardial infarction (MI) patients is a crucial step toward personalized medicine. Genetic factors are known to be associated with an increased risk of cardiovascular
Externí odkaz:
https://doaj.org/article/31e4c87dc8e14b938e9c89cff335c216
Autor:
Issahy Cano, Melissa Wild, Urvi Gupta, Suman Chaudhary, Yin Shan Eric Ng, Magali Saint-Geniez, Patricia A. D’Amore, Zhengping Hu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract The endothelial glycocalyx, located at the luminal surface of the endothelium, plays an important role in the regulation of leukocyte adhesion, vascular permeability, and vascular homeostasis. Endomucin (EMCN), a component of the endothelial
Externí odkaz:
https://doaj.org/article/f866f4dfaaaf46d7b2fa5d0f1a92f343
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 829-843 (2024)
Jue Li,1,* Lusha Zhang,2,* Teng Ge,2 Jiping Liu,1 Chuan Wang,1 Qi Yu1,2 1Engineering Research Center of Brain Health Industry of Chinese Medicine, Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine of Shaanxi Administra
Externí odkaz:
https://doaj.org/article/77fcd7eacf4c4f39b5c4766de07dd5b8
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 1, Pp 246-249 (2024)
Abstract Vascular endothelial growth factor (VEGF) signaling is known to be involved in the antidepressant‐like effects of conventional antidepressants, such as desipramine (DMI), a tricyclic antidepressant, and fluoxetine (FLX), a selective seroto
Externí odkaz:
https://doaj.org/article/cc74544c92bd4e53b9bdb78a800dac3e
Autor:
Seiichiro Ohgaku, Shogo Ida, Natsuko Ohashi, Katsutaro Morino, Atsushi Ishikado, Tsuyoshi Yanagimachi, Koichiro Murata, Daisuke Sato, Satoshi Ugi, Ali Nasiri, Gerald I. Shulman, Hiroshi Maegawa, Shinji Kume, Yukihiro Fujita
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34490- (2024)
Introduction: Endothelial cells have a crucial function in transporting and exchanging various nutrients. O-GlcNAcylation, mediated by O-GlcNAc transferase (OGT), involves the addition of N-acetylglucosamine to proteins and serves as an intracellular
Externí odkaz:
https://doaj.org/article/190378ccdc7a445c9e011d3f60bd64c6
Publikováno v:
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, Vol 31, Iss 10, Pp 7108-7116 (2024)
Introduction: In our current era, the prevalence of cancer and its associated mortality rates have become a pressing concern. As such, finding effective methods for treating cancer has become a matter of significant importance. Abnormal angiogenesis
Externí odkaz:
https://doaj.org/article/38636e79a3e74b3f93fffb7cf4a97b19
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Receptor tyrosine kinases (RTKs) mediate the actions of growth factors in metazoans. In decapod crustaceans, RTKs are implicated in various physiological processes, such molting and growth, limb regeneration, reproduction and sexual differentiation,
Externí odkaz:
https://doaj.org/article/4ed12252abb54525812c57f25a6c0fda
Publikováno v:
Advanced Biomedical Research, Vol 13, Iss 1, Pp 52-52 (2024)
Background: Nowadays, with the increasing prevalence of cancer mortality, finding the best cancer inhibitors is vital. Angiogenesis, which refers to the formation of new blood vessels from existing ones, undergoes abnormal changes in the physiologica
Externí odkaz:
https://doaj.org/article/470135e488d14c8ebd340833ebf91f4d
Autor:
Fatemeh Ebrahimi, Nooshin Reisi Zargari, Mehdi Akhlaghi, S. Mohsen Asghari, Khosrou Abdi, Saeed Balalaie, Mahboobeh Asadi, Davood Beiki
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 899 (2024)
As angiogenesis plays a pivotal role in tumor progression and metastasis, leading to more cancer-related deaths, the angiogenic process can be considered as a target for diagnostic and therapeutic applications. The vascular endothelial growth factor
Externí odkaz:
https://doaj.org/article/b4ff7145cd7d46748cd8174ce6863dbe