Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Vascular/drug effects"'
Publikováno v:
Cardiovascular Research. 116(14):2177-2184
The COVID-19 pandemic is an unprecedented healthcare emergency causing mortality and illness across the world. Although primarily affecting the lungs, the SARS-CoV-2 virus also affects the cardiovascular system. In addition to cardiac effects, e.g. m
Autor:
Marta Gil-Ortega, Beatriz Somoza, María S. Fernández-Alfonso, Marta Viana, M. Paz Lorenzo, Martín Alcalá, Thomas Unger, Raquel González-Blázquez, William A. Boisvert, Ulrike Muscha Steckelings
Publikováno v:
González-Blázquez, R, Alcalá, M, Fernández-Alfonso, M S, Steckelings, U M, Lorenzo, M P, Viana, M, Boisvert, W, Unger, T, Ortega, M G & Somoza, B 2021, ' C21 preserves endothelial function in the thoracic aorta from DIO mice : role for AT2, Mas and B2 receptors ', Clinical Science, vol. 135, no. 9, pp. 1145-1163 . https://doi.org/10.1042/CS20210049
Clinical Science, 135(9), 1145-1163. Portland Press Ltd.
Clinical Science, 135(9), 1145-1163. Portland Press Ltd.
Compound 21 (C21), a selective agonist of angiotensin II type 2 receptor (AT2R), induces vasodilation through NO release. Since AT2R seems to be overexpressed in obesity, we hypothesize that C21 prevents the development of obesity-related vascular al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877a98634f9c9ee846c5eeeae1f14062
https://portal.findresearcher.sdu.dk/da/publications/d3fcf2be-7770-4967-9d40-5384bb58c9fe
https://portal.findresearcher.sdu.dk/da/publications/d3fcf2be-7770-4967-9d40-5384bb58c9fe
Autor:
Sadia Ahmad, Catherine M. Shanahan, Meredith Whitehead, Rick H. van Gorp, Alexander N. Kapustin, Jayanta Bordoloi, Leon J. Schurgers, Malgorzata Furmanik
Publikováno v:
Arteriosclerosis Thrombosis and Vascular Biology, 41(2), 898-914. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Vascular calcification is common among aging populations and mediated by vascular smooth muscle cells (VSMCs). The endoplasmic reticulum (ER) is involved in protein folding and ER
Objective: Vascular calcification is common among aging populations and mediated by vascular smooth muscle cells (VSMCs). The endoplasmic reticulum (ER) is involved in protein folding and ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9d18ff4c1e39d6c3f45b31fc08f507
https://cris.maastrichtuniversity.nl/en/publications/9a49fde3-fac5-4516-af6f-f89b05678874
https://cris.maastrichtuniversity.nl/en/publications/9a49fde3-fac5-4516-af6f-f89b05678874
Autor:
David Mordasini, Anne Labarre, Carlos J. Alcaide-Corral, Laurent A. Decosterd, Chrismita Hegde, Ellen Neven, Mark G. MacAskill, Marc Maillard, Dany Spaggiari, Michel Burnier, David E. Newby, Geert J. Behets, Bastien Castagner, Mattias E. Ivarsson, Patrick C. D'Haese, Antonia E. Schantl, Victoria C. Beindl, Adriana Tavares, Roberto Maj, Anja Verhulst, Jean-Christophe Leroux, Olivier Phan
Publikováno v:
Schantl, A E, Verhulst, A, Neven, E, Behets, G J, D'Haese, P C, Maillard, M, Mordasini, D, Phan, O, Burnier, M, Spaggiari, D, Decosterd, L A, MacAskill, M G, Alcaide-Corral, C J, Tavares, A A S, Newby, D E, Beindl, V C, Maj, R, Labarre, A, Hedge, C, Castagner, B, Ivarsson, M E & Leroux, J-C 2020, ' Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers ', Nature Communications, vol. 11, 721 . https://doi.org/10.1038/s41467-019-14091-4
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature communications, vol. 11, no. 1, pp. 721
Nature communications
Nature Communications, 11 (1)
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature communications, vol. 11, no. 1, pp. 721
Nature communications
Nature Communications, 11 (1)
Myo-inositol hexakisphosphate (IP6) is a natural product known to inhibit vascular calcification (VC), but with limited potency and low plasma exposure following bolus administration. Here we report the design of a series of inositol phosphate analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb9a8129d650ca324178fbd915550a3
https://www.pure.ed.ac.uk/ws/files/134711722/s41467_019_14091_4.pdf
https://www.pure.ed.ac.uk/ws/files/134711722/s41467_019_14091_4.pdf
Autor:
Imo E. Hoefer, Justin C Mason, Johannes Waltenberger, Christian Weber, Tomasz J. Guzik, Desley Neil, Maria Fragiadaki, G. Ed Rainger, Marie-Luce Bochaton-Piallat, Zania Stamataki, Paul C. Evans, Magnus Bäck, Elena Osto
Publikováno v:
Cardiovascular Research
The COVID-19 pandemic is an unprecedented healthcare emergency causing mortality and illness across the world. Although primarily affecting the lungs, the SARS-CoV-2 virus also affects the cardiovascular system. In addition to cardiac effects, e.g. m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643fada1e1849afd51addcbac1a24fdc
https://ruj.uj.edu.pl/xmlui/handle/item/263898
https://ruj.uj.edu.pl/xmlui/handle/item/263898
Autor:
Marius Ringelstein, L. M. Yshii, Ilka Kleffner, Stephen W. Reddel, Brigitte Wildemann, Todd A. Hardy, Markus Schwaninger, Guillaume Martin-Blondel, Nicholas Schwab, Delphine Loussouarn, John Parratt, Marc Pawlitzki, Henrike Plate, Eduardo Beltrán, Catharina C. Gross, Anna R. Tröscher, Tanja Kuhlmann, Tilman Schneider-Hohendorf, Klaus Dornmair, Jan Dörr, Roland S. Liblau, Urvashi Bhatia, Hans Lassmann, Sven G. Meuth, Luisa Klotz, Sebastian Herich, Markus Kraemer, Jan Bauer, Céline Meyer, David-Axel Laplaud, Wolfgang Brück, Romana Höftberger, Michael Barnett, Michael E. Buckland, Andreas Schulte-Mecklenbeck, Heinz Wiendl
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5779. ⟨10.1038/s41467-019-13593-5⟩
Nature Communications, 2019, 10, pp.5779. ⟨10.1038/s41467-019-13593-5⟩
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5779. ⟨10.1038/s41467-019-13593-5⟩
Nature Communications, 2019, 10, pp.5779. ⟨10.1038/s41467-019-13593-5⟩
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
International audience; Neuroinflammation is often associated with blood-brain-barrier dysfunction, which contributes to neurological tissue damage. Here, we reveal the pathophysiology of Susac syndrome (SuS), an enigmatic neuroinflammatory disease w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca645613d7be9f13495f97945a31e9dd
https://www.hal.inserm.fr/inserm-02448919/file/s41467-019-13593-5.pdf
https://www.hal.inserm.fr/inserm-02448919/file/s41467-019-13593-5.pdf
Autor:
Adam D. Gepner, Maria Gisella Cavallo, Alexandra Scholze, Jane Armitage, Frank H Mose, Marina Shargorodsky, Allan D. Struthers, Graham A. Hitman, Thomas Larsen, Faisel Khan, Rinkoo Dalan, Peter Marckmann, Stefan Pilz, Ilaria Barchetta, Ryan A. Harris, Miles D. Witham, Hans Stricker, Louise A. Beveridge, Gavin Dreyer, Carmine Zoccali, Nita G. Forouhi, Robert Clarke, Rajesh Khadgawat, Iain Bressendorff, Seth I. Sokol
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Beveridge, L A, Khan, F, Struthers, A D, Armitage, J, Barchetta, I, Bressendorff, I, Cavallo, M G, Clarke, R, Dalan, R, Dreyer, G, Gepner, A D, Forouhi, N G, Harris, R A, Hitman, G A, Larsen, T, Khadgawat, R, Marckmann, P, Mose, F H, Pilz, S, Scholze, A, Shargorodsky, M, Sokol, S I, Stricker, H, Zoccali, C & Witham, M D 2018, ' Effect of Vitamin D Supplementation on Markers of Vascular Function : A Systematic Review and Individual Participant Meta-Analysis ', Journal of the American Heart Association, vol. 7, no. 11, e008273 . https://doi.org/10.1161/JAHA.117.008273
Beveridge, L A, Khan, F, Struthers, A D, Armitage, J, Barchetta, I, Bressendorff, I, Cavallo, M G, Clarke, R, Dalan, R, Dreyer, G, Gepner, A D, Forouhi, N G, Harris, R A, Hitman, G A, Larsen, T, Khadgawat, R, Marckmann, P, Mose, F H, Pilz, S, Scholze, A, Shargorodsky, M, Sokol, S I, Stricker, H, Zoccali, C & Witham, M D 2018, ' Effect of vitamin D supplementation on markers of vascular function : A systematic review and individual participant meta-analysis ', Journal of the American Heart Association, vol. 7, no. 11, e008273 . https://doi.org/10.1161/JAHA.117.008273
Beveridge, L A, Khan, F, Struthers, A D, Armitage, J, Barchetta, I, Bressendorff, I, Cavallo, M G, Clarke, R, Dalan, R, Dreyer, G, Gepner, A D, Forouhi, N G, Harris, R A, Hitman, G A, Larsen, T, Khadgawat, R, Marckmann, P, Mose, F H, Pilz, S, Scholze, A, Shargorodsky, M, Sokol, S I, Stricker, H, Zoccali, C & Witham, M D 2018, ' Effect of Vitamin D Supplementation on Markers of Vascular Function : A Systematic Review and Individual Participant Meta-Analysis ', Journal of the American Heart Association, vol. 7, no. 11, e008273 . https://doi.org/10.1161/JAHA.117.008273
Beveridge, L A, Khan, F, Struthers, A D, Armitage, J, Barchetta, I, Bressendorff, I, Cavallo, M G, Clarke, R, Dalan, R, Dreyer, G, Gepner, A D, Forouhi, N G, Harris, R A, Hitman, G A, Larsen, T, Khadgawat, R, Marckmann, P, Mose, F H, Pilz, S, Scholze, A, Shargorodsky, M, Sokol, S I, Stricker, H, Zoccali, C & Witham, M D 2018, ' Effect of vitamin D supplementation on markers of vascular function : A systematic review and individual participant meta-analysis ', Journal of the American Heart Association, vol. 7, no. 11, e008273 . https://doi.org/10.1161/JAHA.117.008273
Background: Low 25‐hydroxyvitamin D levels are associated with an increased risk of cardiovascular events, but the effect of vitamin D supplementation on markers of vascular function associated with major adverse cardiovascular events is unclear.Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd27fa41534bb7fd739bd5ae3be116c
https://doi.org/10.1161/jaha.117.008273
https://doi.org/10.1161/jaha.117.008273
Autor:
Carmine Vecchione, Carmine Ostacolo, Albino Carrizzo, Rita Patrizia Aquino, Maria Carmina Scala, Giacomo Frati, Sebastiano Sciarretta, Mariateresa Ambrosio, Eduardo Sommella, Marina Sala, Pietro Campiglia, Antonio D'Amato, Michele Madonna, Serena Migliarino, Giulio Maria Conte, Massimiliano De Lucia, Francesca Sansone, Mario Capunzo
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 73(2)
Considered as a superfood of the future, Spirulina platensis matrix has been extensively used because of its beneficial effect on the management of cardiovascular diseases. However, its nutraceutical properties, bioactive compounds, and molecular mec
Publikováno v:
Basic & Clinical Pharmacology & Toxicology, 122(1), 74-81. Wiley
Leurgans, T M, Bloksgaard, M, Irmukhamedov, A, Riber, L P & De Mey, J G R 2018, ' Relaxing Responses to Hydrogen Peroxide and Nitric Oxide in Human Pericardial Resistance Arteries Stimulated with Endothelin-1 ', Basic & Clinical Pharmacology & Toxicology, vol. 122, no. 1, pp. 74–81 . https://doi.org/10.1111/bcpt.12843
Leurgans, T M, Bloksgaard, M, Irmukhamedov, A, Riber, L P & De Mey, J G R 2018, ' Relaxing Responses to Hydrogen Peroxide and Nitric Oxide in Human Pericardial Resistance Arteries Stimulated with Endothelin-1 ', Basic & Clinical Pharmacology & Toxicology, vol. 122, no. 1, pp. 74–81 . https://doi.org/10.1111/bcpt.12843
In human pericardial resistance arteries, effects of the endothelium-dependent vasodilator bradykinin are mediated by NO during contraction induced by K + or the TxA 2 analogue U46619 and by H 2O 2 during contraction by endothelin-1 (ET-1), respectiv
Autor:
Nicholas Sperelakis, J.B. Caulfield
From the Proceedings of the Meeting of the American Section of the International Society for Heart Research (ISHR) at Hilton Head, South Carolina, September 21-24, 1983