Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Vasco, Sequeira"'
Regional mechanical dyssynchrony and shortened systole are present in people with Takotsubo syndrome
Autor:
Jan-Christian Reil, Vasco Sequeira, Gert-Hinrich Reil, Paul Steendijk, Christoph Maack, Thomas Fink, Elias Rawish, Ingo Eitel, Thomas Stiermaier
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-9 (2024)
Abstract Background: Takotsubo syndrome is characterized by transient regional systolic dysfunction, left ventricular (LV) dilatation, and edema, often occurring without obstructive coronary artery disease. The mechanisms underlying this stress-induc
Externí odkaz:
https://doaj.org/article/edf4c165239e45cba0deea7df7772cb0
Autor:
Mark T. Waddingham, Hirotsugu Tsuchimochi, Takashi Sonobe, Vasco Sequeira, Md Junayed Nayeem, Mikiyasu Shirai, James T. Pearson, Takeshi Ogo
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 8, Iss , Pp 100072- (2024)
Background: Pulmonary hypertension (PH) often leads to right ventricle (RV) failure, a significant cause of morbidity and mortality. Despite advancements in PH management, progression to RV maladaptation and subsequent failure remain a clinical chall
Externí odkaz:
https://doaj.org/article/c799fd064dab4b7da859a49b8d77c099
Autor:
Marie Oertel, Christian G Ziegler, Michael Kohlhaas, Alexander Nickel, Simon Kloock, Christoph Maack, Vasco Sequeira, Martin Fassnacht, Ulrich Dischinger
Publikováno v:
Endocrine Connections, Vol 13, Iss 3, Pp 1-12 (2024)
Objective: Combination therapies with gut hormone analogs represent promising treatment strategies for obesity. This pilot study investigates the therapeutic potential of modulators of the glucagon-like peptide 1 (GLP-1) and neuropeptide Y (NPY) syst
Externí odkaz:
https://doaj.org/article/4d44b403309248ef925535413a2d6416
Autor:
Jan M. Federspiel, Jochen Pfeifer, Frank Ramsthaler, Jan-Christian Reil, Peter H. Schmidt, Vasco Sequeira
Publikováno v:
Diagnostics, Vol 14, Iss 22, p 2534 (2024)
Hypertrophic cardiomyopathy (HCM) is the most common hereditary cardiomyopathy. It is often caused by mutations of genes encoding for sarcomeric or sarcomere-associated proteins. Despite its clinical importance, divergent definitions are published by
Externí odkaz:
https://doaj.org/article/af1a1e70239549109e3b793c827e4934
Autor:
Mark T. Waddingham, Vasco Sequeira, Diederik W. D. Kuster, Elisa Dal Canto, M. Louis Handoko, Frances S. deMan, Denielli daSilva Gonçalves Bós, Coen A. Ottenheijm, Shengyi Shen, Robbert J. van derPijl, Jolanda van derVelden, Walter J. Paulus, Etto C. Eringa
Publikováno v:
Physiological Reports, Vol 11, Iss 22, Pp n/a-n/a (2023)
Abstract Titin‐dependent stiffening of cardiomyocytes is a significant contributor to left ventricular (LV) diastolic dysfunction in heart failure with preserved LV ejection fraction (HFpEF). Small heat shock proteins (HSPs), such as HSPB5 and HSPB
Externí odkaz:
https://doaj.org/article/2586bb27a6ca48ef989b1e4ca6db635a
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 4, Iss , Pp 100036- (2023)
Hypertrophic cardiomyopathy (HCM) is a frequent inherited form of heart failure. The underlying cause of HCM is generally attributed to mutations in genes that encode for sarcomeric proteins, but the pathogenesis of the disease is also influenced by
Externí odkaz:
https://doaj.org/article/d22b4f365c34488b9d7765bb109279d5
Autor:
Vasco Sequeira, Lili Wang, Paul J.M. Wijnker, Kyungsoo Kim, Jose R. Pinto, Cris dos Remedios, Charles Redwood, Bjorn C. Knollmann, Jolanda van der Velden
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 1, Iss , Pp 100007- (2022)
Background: Hypertrophic cardiomyopathy (HCM) is an autosomal dominant genetic disorder with patients typically showing heterozygous inheritance of a pathogenic variant in a gene encoding a contractile protein. Here, we study the contractile effects
Externí odkaz:
https://doaj.org/article/b360c922580f4c239424f598c7d8a20a
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Heart failure (HF) triggered by cardiovascular and non-cardiovascular diseases is a leading cause of death worldwide and translational research is urgently needed to better understand the mechanisms of the failing heart. For this purpose, rodent mode
Externí odkaz:
https://doaj.org/article/9aade1595a6347aebfa0a51139d711d5
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/7ed3c441f82c41839e53f3e1c49e1fe4
Autor:
Thomas Stiermaier, Jan-Christian Reil, Vasco Sequeira, Elias Rawish, Matthias Mezger, Toni Pätz, Christina Paitazoglou, Tobias Schmidt, Christian Frerker, Paul Steendijk, Gert-Hinrich Reil, Ingo Eitel
Publikováno v:
Journal of the American College of Cardiology. 81:1979-1991
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5d79e7124d39605525870dc641a03af
https://doi.org/10.1016/j.jacc.2023.03.398
https://doi.org/10.1016/j.jacc.2023.03.398