Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Vasantha Brito Babapulle"'
Autor:
David Gonzalez, Rachel Wade, Daniel Catovsky, Estella Matutes, Vasantha Brito-Babapulle, Gareth J. Morgan, David Oscier, Sue Richards, Claire Dearden, Pilar Martinez, Sarah L. Hockley
Background: Deletion of 17p in chronic lymphocytic leukaemia (CLL) is associated with resistance to conventional therapy and a poor clinical outcome. Though TP53 mutations have been described in some of these cases, the extent to which they occur in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f28663c3ce1fc18002846185892e64b
https://ora.ox.ac.uk/objects/uuid:2139a727-c306-4946-a7ba-736f341e9313
https://ora.ox.ac.uk/objects/uuid:2139a727-c306-4946-a7ba-736f341e9313
Autor:
Kerry Fenwick, Claire Dearden, Chris Jones, Hannah C. Rudenko, Monica Else, David Gonzalez, Alan Ashworth, Alan Mackay, Tim Dexter, Vasantha Brito-Babapulle, Gareth J. Morgan, Daniel Catovsky, Estella Matutes
Publikováno v:
Leukemia & Lymphoma. 49:1879-1886
Deletion of the TP53 gene on chromosome 17p13.1 is the prognostic factor associated with the shortest survival in CLL. We used array-based comparative genomic hybridisation (arrayCGH) to identify additional DNA copy number changes in peripheral blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d709a7f3eeea919ba14d5f9dc21739
https://doi.org/10.1080/10428190802345902
https://doi.org/10.1080/10428190802345902
Autor:
K Pearson, Daniel Catovsky, Anthony Carter, Anna Burford, Mark Atherton, Andrew R. Pettitt, Estella Matutes, Angela Douglas, Vasantha Brito-Babapulle, Ke Lin, Paul D. Sherrington
Publikováno v:
Leukemia. 20:737-740
Imperfect correlation between p53 dysfunction and deletion of TP53 and ATM in chronic lymphocytic leukaemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a5ef747f33c19d5f057966aaca84dc
https://doi.org/10.1038/sj.leu.2404120
https://doi.org/10.1038/sj.leu.2404120
Autor:
MO Elnenaei, Ricardo Morilla, Estella Matutes, P Jain, Giada M. Giustolisi, Vasantha Brito-Babapulle, Shayne Atkinson, Daniel Catovsky, Roger A'Hern, A C Wotherspoon, Nilima Parry-Jones
Publikováno v:
Leukemia & Lymphoma. 45:2007-2015
Mantle-cell lymphoma (MCL) is a B-cell malignancy with distinct molecular genetics and pathological features. Peripheral blood involvement has been reported with variable frequency, but information on the natural history of cases presenting with leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81489bd738d54e8a657a6ed75ce87a29
https://doi.org/10.1080/10428190410001723331
https://doi.org/10.1080/10428190410001723331
Autor:
Daniel Catovsky, Imma Attolico, Estella Matutes, Nilima Parry-Jones, Vasantha Brito-Babapulle, Andrew Wotherspoon, Rosa Ruchlemer
Publikováno v:
British Journal of Haematology. 125:330-336
B-prolymphocytic leukaemia with t(11;14) revisited: a splenomegalic form of mantle cell lymphoma evolving with leukaemia We reviewed eight cases that were diagnosed before 1995 with B- prolymphocytic leukaemia (B-PLL) harbouring t(11;14)(q13;q32) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3673f0b9f1074fb980fb363b71d159d
https://doi.org/10.1111/j.1365-2141.2004.04913.x
https://doi.org/10.1111/j.1365-2141.2004.04913.x
Autor:
Benet Nomdedeu, Deepti Radia, Fiona Clark, Geir E. Tjønnfjord, Estella Matutes, Vasantha Brito-Babapulle, Daniel Catovsky, Pietro Leoni, Claire Dearden, Antonio Parreira, Bruno Cazin, Martin J. S. Dyer, Tony Roques, Saad M. B. Rassam, Nicolas Ketterer
Publikováno v:
Blood. 98:1721-1726
T-cell prolymphocytic leukemia (T-PLL) is a chemotherapy-resistant malignancy with a median survival of 7.5 months. Preliminary results indicated a high remission induction rate with the human CD52 antibody, CAMPATH-1H. This study reports results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95715b9023d13bf2d4947a31d0f2a7cc
https://doi.org/10.1182/blood.v98.6.1721
https://doi.org/10.1182/blood.v98.6.1721
Publikováno v:
Leukemia & Lymphoma. 42:1379-1383
T-cell prolymphocytic leukaemia (T-PLL) is an aggressive disease often resistant to conventional chemotherapy. Long lasting remissions with the monoclonal antibody CAMPATH-1H (anti-CD52) have been documented. We describe two unusual T-PLL patients tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211da030adfbe56624e6fa5b378ac8b3
https://doi.org/10.1080/10428190127515
https://doi.org/10.1080/10428190127515
Publikováno v:
Cancer Genetics and Cytogenetics. 121:128-132
Chromosome 8 abnormalities are seen in 80% of patients with T-cell prolymphocytic leukemia (T-PLL). The abnormalities described are idic(8)(p11),t(8;8)(p11;q12),+8, and 8p+ with the involvement of 8p. To localize 8p11–p12 breakpoints in T-PLL, meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcb04cb6b1a55584cf4744c1a6213210
https://doi.org/10.1016/s0165-4608(00)00239-9
https://doi.org/10.1016/s0165-4608(00)00239-9
Autor:
Estela Matutes, S. Watson, Vasantha Brito-Babapulle, Pawel Kaczmarek, Rifat Hamoudi, H Maljaie, Daniel Catovsky
Publikováno v:
British Journal of Haematology. 110:180-187
In a series of 24 patients with chronic T-lymphoid disorders [13 T-prolymphocytic leukaemia (T-PLL) and 11 Sezary syndrome] we have studied (i) chromosome 17p abnormalities and p53 allele deletion by fluorescence in situ hybridization; (ii) mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e18be6dc06d6ddabe2ae928dcbdee17
https://doi.org/10.1046/j.1365-2141.2000.02174.x
https://doi.org/10.1046/j.1365-2141.2000.02174.x
Autor:
Toon Min, Daniel Catovsky, Monika Conchon, Alison Crawford, S. Hoda Maljaie, Vasantha Brito-Babapulle, Aidan P. McManus, Estelle Matutes
Publikováno v:
Cancer Genetics and Cytogenetics. 95:137-140
The translocation t(12;22)(p13;q11) has been consistently described in myeloid malignancies and shown to result from a fusion between the TEL and MN1 genes. Previously described deletions of 12p in acute lymphoblastic leukemias have been recently sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95a055f8f4f73ed208adae44dee9a16
https://doi.org/10.1016/s0165-4608(96)00257-9
https://doi.org/10.1016/s0165-4608(96)00257-9